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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 193055 sökträffar

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We present a new analytical equation of state (EOS), which correctly models high pressure theory and fits well to the experimental data of E-Fe, SiO2, Mg2SiO4, and the Earth. The cold part of the EOS is modeled after the Varpoly EOS. The thermal part is based on a new formalism of the Gruneisen parameter, which improves behavior from earlier models and bridges the gap between elasticity and thermo

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Aim: Head injury is the most common trauma occurring in syncope. We aimed to assess whether syncope as cause of head-trauma affects short-and long-term prognosis. Methods: From a database retrospective analysis of 97,014 individuals attending Emergency Department (ED), we selected data of patients with traumatic head injury including age, gender, injury mechanism, brain imaging, multiple traumas,

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The sulfur L-shell photoelectron spectrum of the carbon disulfide molecule has been studied using monochromated synchrotron radiation with a photon energy of 250 eV. The spectrum is atomic like, showing three major bands that can be associated with the sulfur (2p-1)2P3/2,12 and (2s-1)2S1/2 ionic states. A closer inspection shows that the 2P3/2 state is further split into two components separated b

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Importance: Accurate and up-to-date estimates on incidence, prevalence, mortality, and disability-adjusted life-years (burden) of neurological disorders are the backbone of evidence-based health care planning and resource allocation for these disorders. It appears that no such estimates have been reported at the state level for the US. Objective: To present burden estimates of major neurological d

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This contribution analyses the first decision by the Court of Justice of the European Union (CJEU) on the qualification and regulation of stand-alone software as medical devices. Referring to the facts of the case and the applicable EU regulatory framework, the Court specifically found that prescription support software may constitute a medical device. This would even be the case where the softwar

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Background Norwood surgery provides a palliative surgical option for hypoplastic left heart syndrome and has been available in Sweden since 1993. The practice of prenatal ultrasound screening was gradually implemented in the same era, resulting in an increased prenatal detection rate. Our primary aims were to study changes in the incidence of live births, prenatal detection rate, and the terminati

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BACKGROUND AND PURPOSE: Previous studies of familial risks have often combined ischemic and hemorrhagic stroke even though it seems unlikely that these 2 very different pathological conditions are under the same genetic influence. This study is the first to investigate the concordant (same subtype) and disconcordant (different subtype) association between ischemic and hemorrhagic stroke.METHODS: D

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Background Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index (BMI) and a comprehensive set of BMI categories that cover underweight to obesity in children and adolescents, and to compare trends with those of adults. Methods We pooled 2416 popu

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The paper suggests conditions for presence of quadratic Lyapunov functions for nonlinear observer based feedback systems with an 'input nonlinearity' in the feedback path. Provided that the system using state feedback satisfies the Circle Criterion (i.e., when all states can be measured), we show that the extended system with only output feedback control from a (full state) Luenberger-type observe

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Escherichia coli 83972 is a clinical asymptomatia bacteriuric isolate that is able to colonize the human urinary bladder without inducing an immune response. Here we demonstrate that one of the mechanisms by which this strain has become attenuated is through the mutation of its genes encoding type I and P fimbriae.

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Endo-@b-1,4-d-mannanases (@b-mannanase; EC 3.2.1.78) are endohydrolases that participate in the degradation of hemicellulose, which is closely associated with cellulose in plant cell walls. The @b-mannanase from Trichoderma reesei (Man5A) is composed of an N-terminal catalytic module and a C-terminal carbohydrate-binding module (CBM). In order to study the properties of the CBM, a construct encodi

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Hypertension has been associated with raised plasma levels of complement factor 3 and 4 (C3 and C4). The nature of this association is unclear. This population-based longitudinal study explored whether C3 or C4 is associated with development of hypertension. Blood pressure and plasma levels of C3 and C4 were determined in 2178 healthy men, aged 35-50 years, initially without treatment for hyperten

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Ammoxidation of 3-picoline to nicotinonitrile was studied on V2O5, V6O13, and V2O4 catalysts in a fixed-bed integral reactor. The activity studies showed that V6O13 was the most active and selective catalyst of the pure oxides, with a maximum yield of 76% nicotinonitrile at 365 °C. The maximum yield on V2O5 catalyst was 34%, and was obtained at a higher temperature, 458 °C. V2O4 was found to be in

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This study investigated the ward atmosphere of a psychiatric work rehabilitation unit and its relationships to clients' satisfaction with the unit and client motivation, operationalised as proneness to set personal goals for their rehabilitation. The Community-oriented Programs Environment Scale was used and 52 clients participated. Their report of the ward atmosphere was in accordance with recomm

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Testicular germ cell cancer is preceded by a pre-invasive stage called carcinoma-in-situ (CIS). The majority, if not all cases of CIS will progress into invasive cancer. Today, the only reliable way of diagnosing CIS is by performing open testicular biopsy. There is an ongoing search for non-invasive techniques for diagnosing early testicular neoplasia. The possibility of using ultrasound of the t