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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 192776 sökträffar

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This study questions the linear and top-down planning and implementation methods of mainstream development projects, as they do not seem to: achieve its expected outcomes; respond to the complex development context; or allow development beneficiaries to be a part of deciding their own development, despite promotions of inclusive approaches. The purpose was to explore if collaboration could serve a

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The 21st century has developed so quickly digitally that information spreads so quickly through e-word-of-mouth. To effectively communicate, companies have to find a way to spread their own messages in a fast, unique way to entice their publics. In the fashion industry, instead of using their own websites and social media, which can be viewed as untrustworthy, many companies turn to partnerships w

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It is not illegal for an undertaking to have dominant position under EU competition law but such undertakings have a special responsibility to ensure that its conduct does not distort competition. Margins squeeze is one of the many different measures that can be construed as an abuse of an undertakings dominant position under Article 102 TFEU. Margin squeeze can be implemented by a vertically-inte

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The primary purpose of this thesis is to provide a framework for assessing potential effects of disruptive innovation at an industry level. The findings of our primary purpose will contribute to the theoretical field of disruptive innovation and have practical relevance. In addition we also have a secondary purpose, which is that this thesis shall describe how the mobile network operators have bee

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Internal displacement is a relatively new issue in the international agenda, in general, and in research, in particular. However, due to the steady increase in the number of displaced persons globally, this problem becomes more and more visible. This study sees internally displaced persons as marginalized and subaltern group, which is, however, potentially able to start struggle for recognition, w

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This masters thesis in Sociology of Law is a comparative study which explores Europeanization, or more specifically how an EU directive is interpreted by the relevant bureaucratic institutions of a selection of EU countries. Through a discourse analysis based on gender theory, it is shown that from currently developing EU legislation on work permits emerges a policy of differentiation between migr

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I September 2009 öppnade den nya konventionen om godsbefordran till sjöss för signering i Rotterdam. Om den nya konventionen lyckas i det den har intention att göra, vilket är att harmonisera reglerna om godsbefordran till sjöss, kommer den nästan hundra år gammal regimen Haag reglerna att försvinna. Dessa konventioner reglerar tillsammans med Haag-Visby och Hamburg reglerna ansvaret för skada på In September 2009, the new convention concerning carriage of goods by sea opened for signing in Rotterdam. If the convention succeeds in what it sets out to do, harmonising the carriage of goods by sea regulations throughout the world, the almost a century old regime of the Hague Rules will be discarded. These conventions, together with the Hague-Visby Rules and the Hamburg Rules, regulate the lia

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Testicular germ cell cancer is preceded by a pre-invasive stage called carcinoma-in-situ (CIS). The majority, if not all cases of CIS will progress into invasive cancer. Today, the only reliable way of diagnosing CIS is by performing open testicular biopsy. There is an ongoing search for non-invasive techniques for diagnosing early testicular neoplasia. The possibility of using ultrasound of the t

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Genome wide association studies (GWAS) have mapped multiple independent cancer susceptibility loci to chr5p15.33. Here, we show that fine-mapping of pancreatic and testicular cancer GWAS within one of these loci (Region 2 in CLPTM1L) focuses the signal to nine highly correlated SNPs. Of these, rs36115365-C associated with increased pancreatic and testicular but decreased lung cancer and melanoma r

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Large, comprehensive studies of the risk for neurologic disorders among long-term survivors of noncentral nervous system (CNS) childhood cancers are lacking. Thus, the aim of our study was to assess the lifetime risk of Nordic non-CNS childhood cancer survivors for neurologic disorders. We identified 15,967 5-year survivors of non-CNS childhood cancer diagnosed in Denmark, Iceland, Finland and Swe

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Epidemiology and prognosis were analyzed in a consecutive, population‐based series of 137 patients with malignant fibrous histiocytoma of soft tissue in the extremities and trunk wall, with a complete follow‐up of minimum 3 years. All but one patient were treated by surgery in 28 cases combined with adjuvant radiotherapy or chemotherapy. The annual incidence was 0.42/105. The ratio men to women wa

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Transformation, transition and regime shift are increasingly applied concepts in the academic literature to describe changes in society and the environment. Ecosystem services represent one framework that includes the implicit aim of supporting transformation towards a more sustainable system. Nevertheless, knowledge and systematic reviews on the use of these concepts within ecosystem services res

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Although researchers across the social sciences speak of a linguistic turn, most research exploring culture still assumes a traditional perspective on language, which conceives meaning as representation. Yet, Wittgenstein convincingly criticized the epistemological basis of such a perspective, offering an alternative view on language. The paper begins by explaining the central points of a performa

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Streptococcus pyogenes infects over 700 million people worldwide annually. Immune evasion strategies employed by the bacteria include binding of the complement inhibitors, C4b-binding protein (C4BP) and Factor H in a human-specific manner. We recently showed that human IgG increased C4BP binding to the bacterial surface, which promoted streptococcal immune evasion and increased mortality in mice.

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The Python Module Coupler (PyMoC) is a tool for co-simulation of Aspen Plus Dynamics modules that together make up an overall process flowsheet. The tool requires only user input in the form of file paths to Aspen Plus Dynamics modules, and it is able to automatically make the required connections there between, and keep track of the simulation whilst updating the streams regularly. This contribut

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Serum levels of Anti-Mullerian Hormone (AMH) have been shown to be biomarker for prediction of the quantitative aspects of ovarian reserve. On the male side, sperm chromatin structure assay (SCSA) DNA fragmentation index (DFI) has been demonstrated to be an important predictor of outcomes in standard IVF procedures but to less degree in intracytoplasmic sperm injection procedures (ICSI). The purpo