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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 192776 sökträffar

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Increasing awareness and change in attitudes towards environment has given rise to the sustainable development and this development has stimulated environmental innovations globally in the last years. The recent studies show that in near future there will be more packaging solutions from renewable resources. The purpose of this thesis is to investigate how a brand owner using renewable packaging m

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This thesis concentrates on one of the indirect Dark Matter (DM) detection methods, namely through observations of Very High Energy (VHE) $\gamma$-ray signals from DM annihilation (or decay) in cosmic sources using the Imaging Atmospheric Cherenkov Technique (IACT). We discuss the particle physics and astrophysical aspects of those observations and perform several calculations which lead to an est

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This paper explores Europeanization of the Czech Ministry of Foreign Affairs by looking at the impact of the Common Foreign and Security Policy (CFSP) on the Ministry. Despite being intergovernmental, voluntary, governed by treaties and not laws previous studies suggest that CFSP has an impact on the domestic arena. The analysis is based on the conceptual framework developed by Smith (2000) in whi

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Title: The use of art for branding purposes - A study of Louis Vuitton’s art collaborations Louis Vuitton’s creative director, Marc Jacobs, personally describes the fine arts as being higher up in the social hierarchy than fashion. After all, it is known as the ultimate luxury item. This essay will explore the way that the brand uses art in various ways as a means of branding. After extensive res

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BACKGROUND: Extended-spectrum cephalosporin-resistant Enterobacteriaceae (ESCRE) are an increasing healthcare problem in both human and veterinary medicine. The spread of ESCRE is complex with multiple reservoirs and different transmission routes. The aim of this study was to investigate if ESCRE carriage in dogs is more prevalent in households with a known human carrier, compared to households wh

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The scFv antibody towards the Burkholderia pseudomallei exotoxin was previously constructed by phage display and exhibited good specificity towards the exotoxin. We report here the optimization of the scFv expression in an E. coli expression system. Four different E. coli strains (ER2537, TG1, HB2151, and XL1-Blue) were examined for optimal expression of the scFv protein. Two types of carbon sourc

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Background. Randomised trials suggest that therapy with aromatase inhibitors improves survival in breast cancer compared with tamoxifen therapy in postmenopausal cases with hormone receptor positive breast cancer. Whether these results from randomized studies transform into the general population is unknown. We have therefore compared survival for all breast cancer cases in Sweden diagnosed 2000-2

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Purpose: To evaluate inter- and intrareader agreement in breast percent density (PD) estimation on clinical digital mammograms and central digital breast tomosynthesis (DBT) projection images. Materials and Methods: This HIPAA-compliant study had institutional review board approval; all patients provided informed consent. Breast PD estimation was performed on the basis of anonymized digital mammog

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Exposure to some polycyclic aromatic hydrocarbons (PAH) increases the risk of cancer and is common, particularly for workers in occupations such as chimney sweeping. In exposed workers, screening of early cancer-related markers provides important information to identify individuals at risk. Here, we aimed to elucidate the associations between PAH exposure and serum levels of cancer-related protein

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Background: This preclinical study in humans was designed to selectively induce delayed nociceptive pain responses to individually titrated laser stimulation, enabling separate bedside intensity scoring of both immediate and delayed pain. Methods: Forty-four (fourteen female) healthy volunteers were subjected to repeated nociceptive dermal

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The hygroscopic behavior of sub-micrometer atmospheric aerosol particles was studied with a Tandem Differential Mobility Analyzer (TDMA) at a field site in the Po Valley, Italy. The measurements were done in a continental polluted aerosol during the CHEMDROP fog and haze field experiment at San Pietro di Capofiume in November 1994. In this study, hygroscopic diameter growth factors of individual p

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The male genital tract is rich in proteases, delivered by the male accessory sex glands, that are delicately balanced in their action by serpins, non-serpin class protease inhibitors and other regulatory mechanisms. Still, the biological function of the serpins and their target enzymes in the male genital tract and possible involvement in the regulation of normal reproductive function mainly remai

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Iodixanol (IDX) is a water soluble opacifier widely used in radiographical examinations of blood vessels and neural tissue, and it has been suggested as a potential contrast media in acrylic bone cement. The effect of the iodixanol particle size on the polymerisation process of the bone cement, the molecular weight, and the quasi-static mechanical properties have been investigated in this article.

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Purpose: The purpose of this paper is to identify the impact of enterprise systems (ESs), in particular radio frequency identification (RFID) and enterprise resource planning (ERP) systems, on supply chain management (SCM). The results of this conceptual paper demonstrate that ERP and RFID systems contribute to SCM by improving supply chain integration. Supply chain integration occurs to facilitat

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In the photoreceptors of the retina, the second-messenger molecule cyclic guanosine monophosphate (cGMP) occupies centre stage in the phototransduction cascade. Remarkably, cGMP is also involved in hereditary photoreceptor degeneration caused by a variety of different genetic insults. This provides an entry point for the development of inhibitory cGMP analogues for a mutation-independent treatment