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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 193220 sökträffar

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Folate's role in breast cancer development is controversial. Not only estrogen receptor (ER) alpha status, but also ERbeta status of tumors may have confounded results from previous epidemiological studies. We aimed to examine associations between plasma folate concentration and postmenopausal breast cancer defined by ER status. This nested case-control study, within the Malmö diet and cancer coho

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Heparin-binding protein (HBP) is an inducer of vascular endothelial leakage in severe infections. Fluid accumulation into alveoli is a general finding in acute respiratory distress syndrome (ARDS). Severe acute respiratory failure with ARDS is a complication of influenza A(H1N1) infection. Accordingly, we studied the HBP levels in critically ill patients with infection of influenza A(H1N1).Critica

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Poly(acrylamide-allyl glycidyl ether) [poly(AAm-AGE)] cryogel was prepared by bulk polymerization which proceeds in an aqueous solution of monomers frozen inside a glass column (cryo-polymerization). After thawing, the monolithic cryogel contains a continuous polymeric matrix having interconnected pores of 10-100 mu m size. Cibacron Blue F3GA was immobilized by covalent binding onto poly(AAm-AGE)

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In order to reconstruct the late Pleistocene seismic stratigraphy, 550 km of high-density 3.5 kHz subbottom seismic-reflection profiles were recorded within a 70 km(2) area in the narrow offshore border zone between Germany and Denmark. A depositional unit 3 was analysed for its seismic facies association, and in the central study area mound, oblique, channel, reflection-free, shingled, hummocky,

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Identifying mechanisms behind assortative mating is central to the understanding of ecological divergence and speciation. Recent studies show that populations of the freshwater isopod Asellus aquaticus can rapidly become locally differentiated when submerged Chara vegetation expands in lakes. In the novel Chara habitat, isopods have become lighter pigmented and smaller than in ancestral reed stand

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Climate variability and climate change are of great concern to economists and energy producers as well as environmentalists as both affect the precipitation and temperature in many regions of the world. Among those affected by climate variability is the Scandinavian Peninsula. Particularly, its winter precipitation and temperature are affected by the variations of the so-called North Atlantic Osci

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Clinical physiologists in Sweden are physicians (the majority with a PhD degree) with thorough training in system physiology and pathophysiology. They investigate patients in a functional approach and are engaged in basic and applied physiology teaching and research. In 1954, clinical physiology was founded as an independent academic and clinical discipline by the Swedish government to ensure "con

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Introduction: Messenger RNA (mRNA) changes in the small intestine in response to acute mesenteric ischaemia (AMI) could offer novel diagnostic possibilities, but have not been described. The aim was to characterize the mRNA response to experimental AMI. Materials and methods: Twelve pigs underwent catheterisation of the superior mesenteric artery with injection of polivinylalcohol embolisation par

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In high-elevation streams of western Colorado, mayflies (Baetis bicaudatus) develop taster, but mature at a smaller size where trout are present compared to streams where fish are absent. These life history traits reduce the time of larval exposure to trout predation, but Cost reduced fecundity. We designed a field experiment involving manipulation of whole streams to determine whether these chang

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Objective:To study the effect to recommend no snacks vs three snacks per day on 1-year weight loss. The hypothesis was that it is easier to control energy intake and lose weight if snacks in between meals are omitted.Subjects/Method:In total 140 patients (36 men, 104 women), aged 18-60 years and body mass index>30 kg/m(2) were randomized and 93 patients (27 men, 66 women) completed the study. A 1-

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OBJECTIVES: Despite the recent introduction of new peroral drugs as well as neurosurgical methods for Parkinson's disease, treatment of late stage parkinsonian patients remains difficult and many patients become severely handicapped because of fluctuations in their motor status. Injections and infusions of apomorphine has been suggested as an alternative in the treatment of these patients, but the

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Pregnancy in a rudimentary horn of a bicornuate uterus is a rare and often fatal event. A case is presented of such a pregnancy detected in the second trimester routine ultrasonographic examination.

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By precipitating a complex salt Ly(OS)(8) of the positively charged protein lysozyme and the anionic surfactant octyl sulfate OS-, one can generate a true ternary system: water-Ly(OS)(8)-NaOS. Using NMR diffusometry and U spectroscopy measurements the thermodynamic parameters of the association processes have been determined. The solubility product of the complex salt, K-s, is 10-(28) M-9.(1) On