Filtyp
The pH and salt dependent self-association of hen egg-white lysozyme (HEWL) has been studied extensively, mainly by scattering techniques, but it has proven difficult to distinguish oligomerization from long-range interactions. Because HEWL is the principal model system in studies of protein crystallization, it is important to establish its oligomerization behavior unambiguously. Here, we address
In-hospital patients may suffer unexpected death because of suboptimal monitoring. Early recognition of deviating physiological parameters may enable staff to prevent unexpected in-hospital death. The aim of this study was to evaluate short- and long-term effects of systematic interprofessional use of early warning scoring, structured observation charts, and clinical algorithms for bedside action.
We report on the first observation of the macroscopic (long-range) phase separation in Si-rich oxide SiOx(x<2) obtained by continuous-wave laser annealing of free-standing SiOx films. The effect is analyzed by a unique combination of microscopic methods (Raman, transmission, photoluminescence, and infrared spectroscopy, transmission electron microscopy, electron energy loss spectroscopy, and x-ray
Global maritime security has been a subject of analysis and debate in the West since the onset of the European expansion. This article distinguishes four main periods with regard to the doctrines and practices of global maritime security since c. 1450, during which the role of the state in relation to private actors has shifted. As a concept of global policy making, however, maritime security only
Cognitive ability strongly aggregates in families, and prior twin and adoption studies have suggested that this is the result of both genetic and environmental factors. In this study, we used a powerful design-home-reared and adopted-away cosibling controls-to investigate the role of the rearing environment in cognitive ability. We identified, from a complete national Swedish sample of male-male s
Chondroadherin (CHAD) is a leucine-rich protein promoting cell attachment through binding to integrin alpha(2)beta(1) and syndecans. We observed that CHAD mRNA and protein were lower in bone biopsies of 50-year-old to 65-year-old osteoporotic women and in bone samples of ovariectomized mice versus gender/age-matched controls, suggesting a role in bone metabolism. By the means of an internal cyclic
Particles in the atmosphere are of concern due to their toxic properties and effects on climate. In coastal areas, ship emissions can be a significant anthropogenic source. In this study we investigated the contribution from ship emissions to the total particle number and mass concentrations at a remote location. We studied the particle number concentration (12 to 490 nm in diameter), the mass con
Genetic and environmental factors, including the commensal microbiota, have a crucial role in the development of inflammatory bowel disease. Aberrant activation of the transcription factor NF-κB is associated with chronic intestinal inflammation in mice and humans. Recently, an emerging family of innate lymphoid cells (ILCs) has been identified at mucosal sites contributing to the maintenance of g
Dendroclimatological sampling of Scots pine (Pinus sylvestris L.) has been made in the province of Jamtland, in the west-central Scandinavian mountains, since the 1970s. The tree-ring width (TRW) chronology spans several thousand years and has been used to reconstruct June August temperatures back to 1632 BC. A maximum latewood density (MXD) dataset, covering the period AD 1107-1827 (with gap 1292
The production of municipal solid waste is one central concern for environmental policy, and the socio-materiality of waste – how the organisation of waste streams affects households and other waste producers – is an important issue for sustainability. This article shows how the application of European Union waste policy through its waste hierarchy affects the socio-material status of waste. The w
Inflammation is a well-established risk factor for the development of coronary artery disease (CAD) and acute coronary syndrome (ACS). However, less is known about its influence on the outcome of ACS. The aim of this study was to determine if blood biomarkers of inflammation were associated specifically with acute myocardial infarction (MI) or unstable angina (UA) in patients with ACS.
Abstract in UndeterminedThis paper reviews the current literature on political and ethical consumers, and relates it to the topic of sustainable food consumption. A first aim is to problematise a somewhat simplistic view of the political and ethical consumer found in the literature. The paper sheds light on some of the dilemmas that confront green political consumers. We indicate that most existin
A mononuclear iron(II) complex [FeII(N4PyMe2)(OTf)](OTf)(1), supported by a new pentadentate ligand, bis(6-methylpyridin-2-yl)-N,N-bis((pyridin-2-yl)methyl)methanamine (N4PyMe2), has been isolated and characterized. Introduction of methyl groups in the 6-position of two pyridine rings makes the N4PyMe2 a weaker field ligand compared to the parent N4Py ligand. Complex 1 is high-spin in the solid st
While the role played by the state in stimulating innovation in the private sector has been a prevalent interest in innovation research, studies analysing the impacts of public interventions have usually focused on individual policies, programs or projects. Public stimulation is hence often studied from a relatively restricted and temporarily confined perspective, leaving a macro-level and longer-
Although the overall mortality in cancer is steadily decreasing, major groups of patients still respond poorly to available treatments. The key clinical challenge discussed here relates to the inherent capacity of cancer cells to metabolically adapt to hypoxic and acidic stress, resulting in treatment resistance and a pro-metastatic behavior. Hence, a detailed understanding of stress adaptive resp
