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BACKGROUND: While experimental data suggest that selective intracoronary hypothermia decreases infarct size, studies in patients with ST-elevation myocardial infarction (STEMI) are lacking. AIMS: We investigated the efficacy of selective intracoronary hypothermia during primary percutaneous coronary intervention (PCI) to decrease infarct size in patients with STEMI. METHODS: In this multicentre ra
The Øresund Fixed Link is a 15,9 km road and railway connection between the southerly Swedish city of Malmö and its neighbor across the Øresund strait, Copenhagen, in Denmark. The link, which opened in 2000, consists of an elevated bridge, including a high stay cable bridge, an artificial island, as well as a submerged tunnel. The operators of the link, Øresundsbron Consortium, have recently, as p
Let f be a holomorphic self-map of the unit disc. We show that if log(1−|f(z)|) is integrable on a sub-arc of the unit circle, I, then the set of Carathéodory angular derivatives of f on I is a countable union of Beurling-Carleson sets of finite entropy. Conversely, given a countable union of Beurling-Carleson sets, E, we construct a holomorphic self-map of the unit disc, such that its set of Cara
Recent years have seen the dominance of neoclassical, marginalist and welfarist schools of Competition Law and Economics being challenged more vigorously than ever [See two major collecting works on fairness in economics in: Fennell and McAdams (2013) and Cappelen and Tungodden (2019)]. Although the core assumptions of the neoclassical school regarding overt reliance on rationality and efficiency
The matched phase reassignment, developed to estimate phase synchrony of transient oscillatory signals, is extended into a multitaper phase reassignment (MTPR) method. The method gives perfect time-frequency localization for two transients with zero phase difference and estimates of time locations and oscillatory frequencies in low signal-to-noise ratios. For different signal-to-noise ratios betwe
Akin to Zinc Finger and Transcription Activator Like Effector based transcriptional modulators, nuclease-null CRISPR-Cas9 provides a groundbreaking programmable DNA binding platform, begetting an arsenal of targetable regulators for transcriptional and epigenetic perturbation, by either directly tethering, or recruiting, transcription enhancing effectors to either component of the Cas9/guide RNA c
Within a broader definition of design, as the conception and planning of everything that is artificial, the place of tools is central. With the help of cognitive semiotics in general and Donald’s theory of the evolution of the human mind in particular, we propose a stage model for the evolution of design, consisting of four stages: Proto-design, Simple design, Complex design, and Advanced design,
ZnO-water nanofluid in an inner pipe was experimentally investigated to improve the thermal efficiency of double-pipe heat exchangers. In this work, a 57.6% increase in the Nusselt number was obtained at Re = 14,340 when the ZnO-water nanofluid flowed through a helically corrugated tube. It was found that helical corrugation played a more important role in heat transfer enhancement than thermophys
In synchrotrons, nonuniform fill patterns, which give rise to beam phase transients and a spread in synchrotron tune between bunches, have been observed to damp longitudinal coupled-bunch instabilities driven by higher-order modes in rf cavities. The transients are especially large in the presence of Landau cavities, which are used commonly in storage-ring light sources and particularly in the new
The structure of grafted-from poly(N-isopropylacrylamide) (PNIPAM) brushes is investigated as a function of confining stress and system temperature using neutron reflectometry (NR), numerical self-consistent field theory, and the reanalysis of colloid probe atomic force microscopy (AFM) data from the literature. For NR experiments, confinement is achieved using a custom-made sample environment, an
ATTACHMENT of foot-and-mouth disease virus (FMDV) to its cellular receptor involves a long and highly antigenic loop containing the conserved sequence, Arg-Gly-Asp, a motif known to be a recognition element in many integrin-dependent cell adhesion processes1-7. In our original crystal structure of FMDV the Arg-Gly-Asp-containing loop ('the loop'), located between β-strands G and H of capsid protei
Guaranteeing reliable access to water and clean energy has been one of the most debated topics to promote sustainable development, which has made the Water–Energy Nexus (WEN) a relevant field of study. However, despite much development of the WEN, there are still many gaps to be addressed. One of these gaps is the understanding of temporal features. To address this, this study aimed to identify, c
We have investigated the surface composition of a well-ordered Pt3Sn(111) surface during CO oxidation with ambient pressure X-ray photoemission spectroscopy. Oxidation of tin in the surface coincides with the onset of catalytic conversion, and we observe significant differences in the oxidation state and morphology of the oxide formed depending on the gas composition, with an oxygen-rich mixture l
Popular Abstract in Swedish Tvärsektoriella nätverk mellan myndigheter, näringsliv och olika intressegrupper har tilldelats en allt större betydelse, då det varit en vanlig uppfattning att en hållbar utveckling bäst skapas genom ett gemensamt ansvar. Uppfattningarna om resultaten av dessa initiativ uppvisar dock spektakulära skillnader: från att framstå som oslagbara lösningar på de utmaningar soThe importance of cross-sectoral collaborative initiatives, that is partnerships of governments, civil society and the private sector, was elevated due to the belief that the issues of SD are a collective responsibility of all societal actors. The assessment of these initiatives is ranging dramatically; from giving them a status of an unbeatable solution for the SD challenges, to blaming them for
OBJECTIVE: Treatment with dopamine agonists has been associated with cardiopulmonary fibrotic reactions, predominantly in patients treated for Parkinson's disease. To our knowledge, these reactions have previously not been associated with low-dose cabergoline treatment for hyperprolactinaemia. METHOD: A case of constrictive pericarditis in a patient treated with cabergoline for hyperprolactinaemia
Although it is known that college students have a high alcohol consumption, less is known about the long-term drinking trajectories amongst college students and, in particular, students living in residence halls, known to be high-risk drinkers. Over four consecutive years, the drinking habits of 556 Swedish residence hall students were analyzed. The main instruments for measuring outcome were AUDI
Despite the spatially homogenous summer temperaturepattern in Fennoscandia, there are large spreadsamong the many existing reconstructions, resulting in anuncertainty in the timing and amplitude of past changes.Also, there has been a general bias towards northernmostFennoscandia. In an attempt to provide a more spatiallycoherent view of summer (June–August, JJA) temperaturevariability within the l
