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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 193232 sökträffar

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By sending a questionnaire (response rate 93%) to 321 women with a history of venous thromboembolism and previous coagulation tests, 72 patients were identified who had a total of 87 pregnancies after the thromboembolic episode. The main aim of the study was to analyze the influence of prophylaxis during pregnancy and delivery on the development of further thromboembolic complications. During preg

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The Kernel Density Estimator (KDE) is a versatile nonparametric technique with very good theoretical properties. It is used to obtain "smoothed histograms," which allows several distributions to be presented and analyzed more easily on one graph, and direct combination into average distributions. The application of the KDE method as a visual aid for the analysis of distributions of muscle fiber ar

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The major myeloid blood cell lineages are generated from hematopoietic stem cells by differentiation through a series of increasingly committed progenitor cells. Precise characterization of intermediate progenitors is important for understanding fundamental differentiation processes and a variety of disease states, including leukemia. Here, we evaluated the functional in vitro and in vivo potentia

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Simulations with the Explicit Microphysics Model (EMM) of a case of lightly precipitating, glaciated stratiform cloud are presented. This frontal cloud was observed by the UK Met Office C-130 aircraft and the dual-polarization radar at Chilbolton in southern England. The Hallett-Mossop (H-M) process was found to cause extremely high number concentrations of crystal columns of up to almost 1000 1(-

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Box jellyfish, or cubomedusae (class Cubozoa), are unique among the Cnidaria in possessing lens eyes similar in morphology to those of vertebrates and cephalopods. Although these eyes were described over 100 years ago, there has been no work done on their electrophysiological responses to light. We used an electroretinogram ( ERG) technique to measure spectral sensitivity of the lens eyes of the C

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The Strategic Systemic Thinking (SST) framework is presented as a stepping stone towards enabling the refocusing of organizational analysis in Information Systems (IS). The paper introduces some of the fundamental assumptions regarding the objectives of the SST framework; such as sense making as learning processes build upon communicative actions. The main concepts of the SST framework are present

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In neural transplantation studies, there is an interest in identifying and isolating mesencephalic dopamine (mesDA) neuron precursors that have the capacity to differentiate into fully mature mesDA neurons after transplantation. We report here that in the developing ventral mesencephalon (VM) the proneural gene Neurogenin2 (Ngn2) is expressed exclusively in the part of the ventricular zone that gi

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Despite significant advances in the understanding and modelling of turbulent combustion, no general model has been proposed for simulating flames in industrial combustion devices. Recently, the increase in computational possibilities has raised the hope of directly solving the large turbulent scales using large eddy simulation (LES) and capturing the important time-dependant phenomena. However, th

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Objectives: To describe the patient-reported impact of urinary incontinence (UI) in treatment-seeking women in Europe. Design: PURE was a non-interventional, observational study, which aimed to describe the direct costs of treatment for European women seeking treatment for UI. A secondary Study objective was to describe the impact of UI on health-related quality of life (HRQoL) by UI subtype and s

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The synthesis of a C-2-symmetric cleft molecule 2 based on the fused framework between bicyclo-[3.3. 1] nonane and 4-oxo-5-azaindole, incorporating a self-complementary hydrogen-bonding motif, in both racemic and enantiomerically pure forms is reported. This cleft molecule is reminiscent of analogues of Troger's base though with different cleft dimensions and tilt angles. The framework of 2 provid

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The monograph consists of an extensive survey of psychological and behavioral genetic research on migraine, reports of three empirical studies in this area and an extensive English summary. Study 1 indicated persons with migraine (n=28) drawn from a neurological clinic to have experienced negative psychosocial events to a significantly greater extent during their development than persons free of m

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Popular Abstract in Swedish Fotosyntesen är den process i växter, alger och fotoautotrofa bakterier, där solljusets energi fångas i kemiska föreningar och levande materia. Avsikten med konstgjord fotosyntes är på lång sikt att framställa bränsle (t ex vätgas) med hjälp av solenergi och vatten, enligt fotosyntesens principer. I växter är den centrala principen för denna process, som är den viktigasPhotosynthesis is the process by which light energy is converted into chemical products, in photoautotrophic bacteria, algae and plants. The principal idea is the production of reducing agents by photo-induced oxidation of a sacrificial electron donor. Photosystem II in plants, algae and cyanobacteria, absorbs light and catalyzes the oxidation of water, liberating electrons that are used to form r

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In this paper, it is shown that stacking dielectric sheets above planar self-complementary antenna elements can reduce the degrading effect of the ground plane and hence be used to design ultra-wideband antennas

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Popular Abstract in Swedish En central fråga av både teoretisk och praktisk betydelse är varför vissa företag är mer framgångsrika - vilket ofta uttrycks som att de har större konkurrensfördelar - än andra. Speciellt uppkommer frågan då vissa fabriker inom samma företag år efter år uppvisar ett bättre ekonomiskt resultat än andra. Fokus i denna avhandling är att förstå varför så sker inom ett utvaThe most central question in the strategic management literature is why some firms are more successful than others, often expressed as an aim to understand sources of competitive advantage. In this thesis, an empirical observation is made that a number of manufacturing plants belonging to the same firm show sustainable differences in financial success, and the question is why. The main theoretical

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Rigid or conformationally restricted compounds are intresting from a pharmacological point of view since they do not have to pay the entropy penalty paid by more flexible molecules in binding to e.g. a protein. In this thesis, synthetic transformations of a rigid tetracyclic oxanorbornene scaffold are described, yielding novel compounds with low molecular weight, rigid framework and high oxygen co

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In spite of the growing importance of planned,centrally managed and enclosed shopping centres in the retailing sector,the understanding concerning sources and outcomes of customer satisfaction with this kind of shopping malls is limited.This paper develops and vali- dates a conceptualisation of shopping mall satisfaction based on ?eld studies in Sweden.The results show that eight underlying factor