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Online evaluations are one of the most important innovations in tourism in recent years, often combining a review/rating (business-specific evaluation) and a ranking (inter-business comparison). As online reputation determines economic success, tourism managers may be tempted to manipulate online content. This paper presents the results from a qualitative study involving 20 hotel managers in south
When Octavian in 27 BC was given the title of Augustus, a shield was set up in the senate inscribed with four virtues; virtus, clementia, iustitia, and pietas. Aeneas, the great ancestor of Octavian, is frequently praised for pietas, virtus, and iustitia in the Aeneid. Regarding clementia, however, Vergil is conspicuously silent. Indeed, in the battle scenes of books 10 and 12, Aeneas refuses to s
The ability to detect a virtualized environment has both malicious and non-malicious uses. This paper reveals a new exploit and technique that can be used to remotely detect VMware Workstation, VMware Player and VirtualBox. The detection based on this technique can be done completely passively in that there is no need to have access to the remote machine and no network connections are initiated by
Context: Due to the complexity and challenging nature of radical prostatectomy (RP), it is likely that both short-and long-term outcomes strongly depend on the cumulative number of cases performed by the surgeon as well as by the hospital. Objective: To review systematically the association between hospital and surgeon volume and perioperative, oncologic, and functional outcomes after RP. Evidence
This article reports on the successful stabilization of the carrier-envelope phase of a 1-kHz laser system that includes a large grating stretcher, a regenerative amplifier, a multipass amplifier and a grating compressor. Phase stability for pulse energies up to 6 mJ is demonstrated using electronic feedback to the oscillator locking electronics as well as feedback via an acousto-optic programmabl
In this article, I will apply parts of the method introduced by Linda Hutcheon in her recently reedited book A Theory of Adaptation (2010) and try to answer the question “why” an adaptation is made. I will particularly study three complex cases of adaptation, which might even put into question the definition of adaptation itself, but I will concentrate on aspects related to immersion and self-refe
The cysteine proteases are enzymes found in every kingdom of life. Clan CA is the largest of the cysteine protease clans, with members all displaying a Cys/His/Asn(Asp) catalytic triad responsible for hydrolysing the peptide bond within the substrate. To regulate the activity of the proteases, another group of proteins act as natural inhibitors (cysteine protease inhibitors) and bind to the protea
Erysipelas is a common and severe infection where the aetiology and optimal management is not well-studied. Here, we investigate the clinical features, bacteriological aetiology, and treatment of erysipelas.
Invasive infections remains one of the leading causes of death due to infections over the world, and efficient treatment remains elusive. One of the major causes of sepsis and other invasive infections is pathogenic streptococci that cause a wide range of clinical manifestations in humans. Group A and group G streptococci have both been shown to cause both infections of milder ranges as well as se
Background: Randomized placebo-controlled trials represent the gold standard in evaluating healthcare interventions but are rarely performed within orthopedics. Ethical concerns or well-known challenges in recruiting patients for surgical trials in general have been expressed and adding a placebo component only adds to this complexity. The purpose of this study was to report the challenges of recr
Characterization of macromolecules and colloids is an area of considerable interest. Asymmetrical flow field-flow fractionation (AF4) has become a well-established method, but many potential users possess limited knowledge of its capabilities, or how it can provide additional information or serve as validation to the traditional analytical techniques. This review article highlights several practic
We present experimental measurements of the coherence of an undulator synchrotron radiation source near to the diffraction limit condition. These measurements have been done following two objectives. The first one is to verify a fundamental point of the theory of synchrotron radiation. To our knowledge, since it has been re-written by Geloni et al. [1], no experimental verification to validate the
Magnetic properties of 20 nm thick (Ga,Mn)As layer deposited on (Ga,ln)As buffer with very large epitaxial tensile strain are investigated. Gal,In,As buffer with x=30% provides a 2% lattice mismatch, which is an important extension of the mismatch range studied so far (up to 0.5%). Evolution of magnetic anisotropy as a function of temperature is determined by magnetotransport measurements. Additio
Anthracyclines, e. g. daunorubicin, doxorubicin, and idarubicin, consist of a tetracycline moiety linked via a glycosidic bond to a sugar residue, usually the aminosugar daunosamine. The anthracyclines are efficient chemotherapeutic agents against cancer, but their use is limited due to cardiotoxicity and induction of multidrug resistance. In the search for new anthracycline analogs, a daunosamine
To explore the potential of grating-based x-ray phase-contrast computed tomography (CT) for preclinical research, a genetically engineered mouse model of pancreatic ductal adenocarcinoma (PDAC) was investigated. One ex-vivo mouse specimen was scanned with different grating-based phase-contrast CT imaging setups covering two different settings: i) high-resolution synchrotron radiation (SR) imaging
In his paper Hypnosis Reconsidered, Resituated, and Redefined (JSE 26(2):297–327), Adam Crabtree, a distinguished expert in the history of hypnosis, maintains that contemporary hypnosis research suffers from conceptual disorder. In his words, he attempts to redefi ne hypnosis in order to provide a stronger ground for future research. We find that his proposed reconsideration of hypnosis as a form
In this paper I discuss how a virtue ethic for the preservation of biodiversity may look like. The starting-point is the virtue ethic proposed by Celia Deane-Drummond. She suggests that the four cardinal virtues of prudence, justice, fortitude and temperance should form the basis of an ethic of nature. Of this four, prudence is the most fundamental. Moreover, Deane-Drummond states that the intelle
Enterprise Risk Management (ERM) is a holistic, integrated approach to managing a company’s risks, in contrast to the so-called “silo-approach” prevalent in many firms in which risks are managed independently of each other. Yet for all the risk exposures that are brought under the corporate umbrella in an ERM initiative, it may be inadequate for addressing the firm’s aggregate risk in terms of the
