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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 195677 sökträffar

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The timing of the ice margin retreat of the Late Glacial Patagonian Ice Sheet (PIS) in southern Patagonia has been the object of discussion for many years. In order to resolve questions about the complex response of the PIS to past climate change, any geological interpretation and data modelling need evaluation against an absolute chronology. The aim of this project is to investigate the applicabi

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A search has been performed for the experimental signature of an isolated photon with high transverse momentum, at least one jet identified as originating from a bottom quark, and high missing transverse momentum. Such a final state may originate from supersymmetric models with gauge-mediated supersymmetry breaking in events in which one of a pair of higgsino-like neutralinos decays into a photon

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Experience of the Port-A-Cath implantable venous access system in 53 children with severe or moderate haemophilia A or B from seven centres in five countries is reviewed. The cumulative duration of follow-up was 1578 months (median 30 months, range 1-114). Of the devices implanted, 70% (37/53) were used without complications (median follow-up 32 months; range 1-114) and the remaining 30% (16/53) w

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Objectives Biologic agents have dramatically changed treatment of rheumatoid arthritis (RA). To date only scarce head-To-head data exist especially when the biological therapies are given as monotherapy without concomitant disease modifying drugs (DMARDs). Thus the objective of the current study is to evaluate treatment response of all available biological therapies with special focus on utility (

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Background: Practice guidelines for childhood posttraumatic stress disorder (PTSD) recommend trauma-focused psychotherapies, mainly cognitive behavioral therapy (CBT). Eye movement desensitization and reprocessing (EMDR) therapy is a brief trauma-focused, evidence-based treatment for PTSD in adults, but with few well-designed trials involving children and adolescents. Methods: Weconducted a single

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Switching from oil to biofuels appears to be good business for the Swedish pulp and paper industry today. Mixing traditional wood fuels with sludge residues makes the transition even more profitable. Public financial support of 159 MSEK has pulled the four pulp and paper industries studied in this thesis to invest another 538 MSEK, creating annual cost savings of 150 MSEK per year. This thesis sho

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Populärvetenskaplig sammanfattning: För att öka tillgången på mat och att generera arbeten och inkomster är det angeläget för utvecklingsländer att öka produktionen inom jordbruket. En förutsättning för detta är att eliminera produktionshinder genom att dels förbättra jordbruksmetoder, dels identifiera olika områden som är lämpliga för olika typer av jordbruk. Denna Minor Field Study (MFS) är utföThe importance of less developed countries to increase the agricultural production, in order to improve food supplies and generate employment and income, requires the removal of resources constraints by improving agricultural practices and identifying land suitable for different agricultural activities. This Minor Field Study (MFS) is made within the present Sida/SAREC-financed research project “R

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This thesis explores the causes and ramifications of representing women in gender-equality advocacy within the realm of International Development cooperation’s. This study shows that through representing the issues of development and the people for whom they are aimed - we risk constructing and reconstructing conceptions of what the postcolonial feminist field of studies calls ´third world differe

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Palmolja finns numer i en rad olika produkter, från margarin till biobränsle, och den globala efterfrågan på palmolja ökar år för år. I Malaysia har produktionen av palmolja ökat mer än 185 gånger sedan år 1961 och idag producerar landet omkring 40 % av världens palmolja. Den enorma tillväxten drivs av bland annat populationsökning, förändrade konsumtionsvanor samt policys som syftar till att öka There is a growing global demand for palm oil – a vegetable oil used in various products such as margarine and biofuel. Since 1961 the Malaysian palm oil production has experienced a 185-fold increase and currently Malaysia produces about 40 % of the world’s palm oil. Malaysia also has one of the world’s richest flora and fauna. The palm oil industry has gained much negative attention in recent ye

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In response to stakeholder expectations, and in line with the life cycle idea, a growing number of corporations are working to influence its suppliers for improved environmental and social performance. The number and diversity of the actors and aspects to consider in global supply chains contributes to the complexity of the task. Most actively engaging in supply chain improvements are companies wi

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This paper outlines the development of the specialist medical physicist role in Sweden. Since introducing certification in 1999, the need for advanced expertise in patient safety, technology, optimization, and regulation became evident. In response, the Swedish Medical Physicist Association and the Swedish Society for Radiation Physics launched a national specialist training program in 2004, furth

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OBJECTIVES: Diabetes mellitus (DM) has a strong genetic component and is a known risk factor for several hand conditions. We aimed to examine whether DM in first-degree relatives is associated with an increased risk of hand surgical diagnoses.DESIGN: A retrospective cohort study.SETTING: Data were collected from a population-based cohort in southern Sweden (Malmö Diet and Cancer Study (MDCS)). Fam

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Background: The risk of stroke associated with carotid artery restenosis after stenting or endarterectomy is unclear. We aimed to compare the long-term risk of restenosis after these treatments and to investigate if restenosis causes stroke in a secondary analysis of the International Carotid Stenting Study (ICSS). Methods: ICSS is a parallel-group randomised trial at 50 tertiary care centres in E

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Background: The role of insulin resistance as a mediator in the association of body mass index (BMI) with site-specific cancer risk has, to our knowledge, never been systematically quantified. Methods: Altogether 510 471 individuals from six European cohorts, with a mean age of 43.1 years, were included. We used the triglyceride glucose product (TyG index) as a surrogate measure for insulin resist

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Optimization of the duration of Structural Health Monitoring (SHM) campaigns is rarely performed. This article provides a utility-based solution to posteriorly determine: i) optimal monitoring durations and ii) the extension of the service life of the welds on a steel bridge deck. The approach is illustrated with a case study focusing on remaining fatigue life estimation of the welds on the orthot

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Background: A time-geographic diary approach is of interest in occupational therapy due to the inclusion of the diarist’s subjective experiences. There are several methods for detecting doing in time, but details needed for analysis are still lacking. The smartphone application POrtable Diary Data collector (PODD), a 24-hr diary based on the time-geographic diary has recently been introduced. Aim:

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Background & aim: Preterm infants risk deficits of long-chain polyunsaturated fatty acids (LCPUFAs) that may contribute to morbidities and hamper neurodevelopment. We aimed to determine longitudinal serum fatty acid profiles in preterm infants and how the profiles are affected by enteral and parenteral lipid sources. Methods: Cohort study analyzing fatty acid data from the Mega Donna Mega stud

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Diagnosis and treatment of patients with suspected chronic coronary syndrome (CCS) currently relies on the degree of coronary artery stenosis and its significance for myocardial perfusion. However, myocardial perfusion can be affected by factors other than coronary stenosis. The aim of this study was to investigate to what extent sex, age, diabetes, hypertension and smoking affect quantitative myo