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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 194760 sökträffar

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A novel method for learning characteristic decision trees is applied to the problem of learning the decision mechanism of coin-sorting machines. Decision trees constructed by ID3-like algorithms are unable to detect instances of categories not present in the set of training examples. Instead of being rejected, such instances are assigned to one of the classes actually present in the training set.

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The influence of several operating parameters on the critical flux in the separation of lactic acid-producing bacteria from fermentation broth was studied using a ceramic microfiltration membrane equipped with a permeate pump. The operating parameters studied were crossflow velocity over the membrane, bacterial cell concentration, protein concentration, and pH. The influence of the isoelectric poi

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Crystallographic screening of the binding of small organic compounds (termed fragments) to proteins is increasingly important for medicinal chemistry-oriented drug discovery. To enable such experiments in a widespread manner, an affordable 96-compound library has been assembled for fragment screening in both academia and industry. The library is selected from already existing protein-ligand struct

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Compartmental diffusion MRI models that account for intravoxel incoherent motion (IVIM) of blood perfusion allow for estimation of the fractional volume of the microvascular compartment. Conventional IVIM models are known to be biased by not accounting for partial volume effects caused by free water and cerebrospinal fluid (CSF), or for tissue-dependent relaxation effects. In this work, a three-co

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Excessive collection of platelets is an unwanted side effect in current centrifugation-based peripheral blood progenitor cell (PBPC) apheresis. We investigated a novel microchip-based acoustophoresis technique, utilizing ultrasonic standing wave forces for the removal of platelets from PBPC products. By applying an acoustic standing wave field onto a continuously flowing cell suspension in a micro

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The isolation of mitochondria from potato tubers (Solanum tuberosum L.) is described, but the methodology can easily be adapted to other storage tissues. After homogenization of the tissue, filtration and differential centrifugation, the key step is a Percoll density gradient centrifugation. The Percoll gradient contains two parts: a bottom part containing Percoll in 0.3 M sucrose, and a slightly

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Deep eutectic solvents (DESs) are often promoted as a more environmentally friendly alternative for ionic liquids and other ionic solvents. Like ionic liquids, DESs can be designed for specific tasks in various chemical environments, but their usage in extraction processes is often significantly hampered by difficulties in recovering the extraction product. To remedy this, various tactics are bein

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Objective: To determine the usefulness and prognostic value of a simplified salivary gland ultrasonography (SGUS) scoring system in primary Sjögren's syndrome (pSS). Methods: Patients with pSS (n=105) and controls (n=57) were evaluated using a simplified SGUS scoring system. Parenchymal homogeneity in salivary glands was graded from 0 to 3, grades 0 (normal) and 1 (mild inhomogeneity) being interp

Genetik och diabetes

Diabetes är en heterogen sjukdom som orsakas av en kombination av miljö och ärftliga riskfaktorer som leder till förhöjt blodsocker genom insulinresistens och/eller insulinbrist. Vi studerar alla typer av diabetes för att förstå hur sjukdomens heterogenitet påverkar sjukdomsförlopp, behandlingsrespons och risk för komplikationer. För detta ändamål använder vi stora populations- och kohortstudier, Diabetes is a heterogeneous disease defined by elevated glucose levels. It is caused by genetic and environmental risk factors that combine to cause dysregulation of glucose metabolism through insulin resistance and/or insulin deficiency. We study all types of diabetes to understand how disease heterogeneity affects progression, response to treatment and risk of complications. To this end we use

Lund University Bioimaging Center

Our mission is to establish a major trans-faculty bio-imaging center at Lund University (Lund University Bioimaging Center), combining knowledge in the fields of medical physics, preclinical and clinical medicine, chemistry, technology and applied mathematics in order to develop imaging methods for the advanced study of human morphology, cellular metabolism and physiological function in health and

Metod upptäcker nya varianter av covid-19-virus – Vetenskap och Hälsa

Metod upptäcker nya varianter av covid-19-virus – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Metod upptäcker nya varianter av covid-19-virus 2025-11-18 Forskare på Malmö universitet har utvecklat en metod som kan upptäcka olika typer av coronavirus med hög precision.

https://www.vetenskaphalsa.se/metod-upptacker-nya-varianter-av-covid-19-virus/ - 2026-10-08

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ABSTRACT Teaching and learning are frequently treated as processes that are separate from each other, while teachers and learners are considered as disembodied entities with a neutral position towards the content which is negotiated. In collective biography writing (CBW), a very different approach is taken. Writing, reading and learning are seen as an integrated whole, where teachers and educators

Lisa Wallander

Universitetslektor och docent i socialt arbete | Fil dr. i sociologi Kontaktinformation E-post: lisa [dot] wallander [at] soch [dot] lu [dot] se Telefon: +46 46 222 03 15Organisation Socialhögskolan Rumsnummer: 447 Hämtställe: 28 WebbplatsLisa Wallanders profil i Lunds universitets forskningsportalAndra roller Universitetslektor Socialhögskolan Docent Professioner och organiseringUndervisningForsk

https://www.soch.lu.se/lisa-wallander - 2026-10-08

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Using a custom-made cDNA microarray, global transcriptional analyses were conducted to identify genes differentially regulated in the pheromone gland as compared to the remaining insect tissue of the moth Agrotis segetum (Noctuidae). A two-fold or larger difference in relative expression levels was found for 227 of 864 genes investigated comparing the two tissues. Unexpectedly, an antennal binding

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Many biopharmaceuticals (BPs) are known to be immunogenic in the clinic, which can result in modified pharmacokinetics, reduced efficacy, allergic reactions and anaphylaxis. During recent years, several technologies to predict immunogenicity have been introduced, but the predictive value is still considered low. Thus, there is an unmet medical need for optimization of such technologies. The genera