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This thesis is focused on geometric computer vision problems. The first part of the thesis aims at solving one fundamental problem, namely low-rank matrix factorization. We provide several novel insights into the problem. In brief, we characterize, generate, parametrize and solve the minimal problems associated with low-rank matrix factorization. Beyond that, we give several new algorithms based o
The aim of this multicenter study was to investigate whether a computer-assisted diagnosis (CAD) system could improve performance and reduce interobserver variation in bone-scan interpretations of the presence or absence of bone metastases. Methods: The whole-body bone scans (anterior and posterior views) of 59 patients with breast or prostate cancer who had undergone scintigraphy for suspected bo
Background and Aim: New SPECT cameras that use CZT detectors in a 360◦ configuration has recently been introduced. Together with Bayesian reconstruction methods employing Median Root Prior (MRP) and Relative Difference Prior (RDP), this constitutes an alternative to Anger-based SPECT for activity quantification. The aim of this thesis is to, by the use of both OS-EM and Bayesian reconstruction met
Background: The aim was to compare bias and precision for 177Lu-SPECT activity-concentration estimation using a dual-headed Anger SPECT system and a ring-configured CZT SPECT system. This was investigated for imaging at 208 keV and 113 keV, respectively. Methods: Phantom experiments were performed on a GE Discovery 670 system with 5/8’’ NaI(Tl) crystal (dual-headed Anger system) and a GE StarGuide
Background: Women with breast cancer have different chances of surviving their disease, depending on where they live. Variations in survival may stem from unequal access to prompt diagnosis, treatment and care. Implementation of the right to health may help remedy such inequalities. The right to health is enshrined in international human rights law, notably Article 12 of the International Covenant
Due to increasing demand for software project managers in industry, efforts are needed to develop the management-related knowledge and skills of the current and future software workforce. In particular, university education needs to provide to their computer science students not only technology-related skills but, in addition, a basic understanding of typical phenomena occurring in industrial (and
X-rays allow to non-destructively investigate biological, chemical or physical processes at thenano-scale. Their high penetration depth in matter allows to investigate samples even in-side sample environments, which would be difficult with complementary methods such astransmission electron microscopy (TEM). The microscopy technique ptychography has beenestablished in X-rayX-rays allow to non-destructively investigate biological, chemical or physical processes at the nano-scale. Their high penetration depth in matter allows to investigate samples even inside sample environments, which would be difficult with complementary methods such as transmission electron microscopy (TEM). The microscopy technique ptychography has been established in X-ray imaging in recent year
Rotational coherent anti-Stokes Raman spectroscopy (CARS) is used for measurements of temperatures and relative species concentrations. The evaluation of a rotational CARS spectrum is normally performed using a least-squares fitting algorithm to find the best-fit theoretical spectrum in a library of spectra calculated at different temperatures and relative concentrations. A general problem is that
A model based on the two‐dimensional stochastic advection‐diffusion equation is developed to forecast properties of individual rain cells in urban areas such as speed and spatial rainfall intensity. Two different modeling approaches are employed, and examples of the results are given. The first approach involves a Gaussian distribution as an analytic solution to the advection‐diffusion equation, w
Immunization of H2(p) and H2(q) congenic C3H mouse strains with the PLP 103-116 peptide elicited two distinct experimental allergic encephalomyelitis (EAE) disease courses. C3H.Q (H2(q)) mice developed an acute-phase disease with classical ascending paralytic signs whereas C3H.NB (H2(p)) developed a highly variable disease course with symptoms originating from CNS above the spinal chord. C3H.Q lac
This master thesis presents the development of a vision-based feedback control system for automating sample placement in a virtual neutron beam emulated using a laser. The thesis was carried out on behalf of the European Spallation Source (ESS) to investigate the feasibility, possibilities and limitations of using a robotic automation system for sample alignment. Due to the radioactive research en
