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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 192801 sökträffar

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We present an optical solution called DMD-PS to boost the dynamic range of 2D imaging spectroscopic measurements up to 22 bits by incorporating a digital micromirror device (DMD) prior to detection in combination with the periodic shadowing (PS) approach. In contrast to high dynamic range (HDR), where the dynamic range is increased by recording several images at different exposure times, the curre

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Background: Identifying individuals at high risk of developing Alzheimer's disease (AD) is important for future therapeutic strategies, and there is a clinical need for diagnostic biomarkers to identify incipient AD. Objective: The aim of the present study was to investigate if the AD-associated A beta peptide pattern recently found in cerebrospinal fluid (CSF) could discriminate between patients

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The implementation of an appropriate pricing policy in an urbanarea could alleviate both environmental and congestion problemsby encouraging a shift towards more sustainable modes oftransportation. However, any positive net social welfare balancedelivered by the policy can hide unacceptable regressive effects.Therefore, it is crucial to investigate any change in relative levelsof accessibility amo

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We present a new concept of synthesis for preparation of molecularly imprinted polymers using a functionalized initiator to replace the traditional functional monomer. Using propranolol as a model template, a carboxyl‐functionalized radical initiator was demonstrated to lead to high‐selectivity polymer particles prepared in a standard precipitation polymerization system. When a single enantiomer o

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Steric clashes pose a challenge when exploring dense protein systems using conventional explicit-chain methods. A minimal example is a single lattice protein confined on a minimal grid, with no free sites. Finding its minimum energy is a hard optimization problem, with similarities to scheduling problems. It can be recast as a quadratic unconstrained binary optimization (QUBO) problem amenable to

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Hybrid photon counting detectors have significantly advanced synchrotron research. In particular, the introduction of large cadmium telluride-based detectors in 2015 enabled a whole new range of high-energy X-ray measurements. This article describes the specifications of the new PILATUS4 cadmium telluride detector and presents results from prototype testing for high-energy powder X-ray diffraction

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Laminins are extracellular matrix glycoproteins that influence the phenotype and functions of many types of cells. Laminins are heterotrimers composed of alpha, beta, and gamma polypeptides. So far five alpha, three beta, and two gamma polypeptide chains, and 11 variants of laminins have been proposed. Laminins interact in vitro with mature blood cells and malignant hematopoietic cells. Most studi

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The majority of human embryonic stem cell lines depend on a feeder cell layer for continuous growth in vitro, so that they can remain in an undifferentiated state. Limited knowledge is available concerning the molecular mechanisms that underlie the capacity of feeder cells to support both the proliferation and pluripotency of these cells. Importantly, feeder cells generally lose their capacity to

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We utilized femtosecond time-resolved resonant inelastic X-ray scattering and ab initio theory to study the transient electronic structure and the photoinduced molecular dynamics of a model metal carbonyl photocatalyst Fe(CO)5 in ethanol solution. We propose mechanistic explanation for the parallel ultrafast intra-molecular spin crossover and ligation of the Fe(CO)4 which are observed following a

EUGLOH

European University Alliance for GLObal Health Om du är intresserad av aktuella områden som hållbarhet, global hälsa, internationellt samarbete eller entreprenörskap kan de möjligheter EUGLOH erbjuder vara något för dig. EUGLOH – European University Alliance for GLObal Health – är ett nätverk av nio europeiska universitet som erbjuder spännande, tvärvetenskapliga aktiviteter med fokus på aktuella

https://www.lu.se/student/internationella-mojligheter/stipendier-studier-och-praktik-utomlands/eugloh - 2026-07-18

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MOx sensors are widely used for sensing gases. In this thesis a variable temperature MOx sensor was used to detect graffiti spray paint and differentiate it from other substances using the sensors sensitivity to different gases at different temperatures using machine learning. The machine learning methods Support Vector Machines, k-Nearest Neighbour and neural networks were evaluated and compared.

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This paper presents an energy-efficient sorted QR decomposition (SQRD) processor for 3GPP LTE-Advanced (LTE-A) systems. The processor adopts a hybrid decomposition scheme to reduce computational complexity and provides a wide-range of performance complexity trade-offs. Based on the energy distribution of spatial channels, it switches between the brute-force SQRD and a low-complexity group-sort QR-

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Electrical characterization of nanowires is a time-consuming and challenging task due to the complexity of single nanowire device fabrication and the difficulty in interpreting the measurements. We present a method to measure Hall effect in nanowires using a three-probe device that is simpler to fabricate than previous four-probe nanowire Hall devices and allows characterization of nanowires with

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NOx pollution from Diesel engines causes over 10 000 premature deaths annually and the trend is increasing. In order to decrease this growing global problem, exhaust after-treatment systems for Diesel engines have to be improved. The most common SCR systems in the market place inject an aqueous Urea solution, DEF that evaporates prior the catalytic surface of the SCR-catalyst. Due to a catalytic r

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An estimation model which uses the gross heat release data and the fuel energy to estimate the total amount of emissions and unburned Hydro Carbon (HC) is developed. Gross heat release data is calculated from a self-tuned heat release method which uses in-cylinder pressure data for computing the energy released during combustion. The method takes all heat and mass losses into account. The method e

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The cepstrum of a random process is useful in many applications. The cepstrum is usually estimated from the periodogram. To reduce the mean square error (MSE) of the estimator, the periodogram may be smoothed with a kernel function. We present an explicit expression for a kernel function which is approximatively MSE optimal for cepstrum estimation. A penalty term has to be added to the minimizatio