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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 193226 sökträffar

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Submicron sized sensors could allow higher resolution in X-ray imaging and diffraction measurements, which are ubiquitous for materials science and medicine. We present electrical measurements of a single 100 nm diameter InP nanowire transistor exposed to hard X-rays. The X-ray induced conductance is over 5 orders of magnitude larger than expected from reported data for X-ray absorption and carrie

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We demonstrate the use of a GaAs-AlGaAs gated tunnel diode (GTD) in an ultra-wideband (UWB) wavelet generator. An inductor is integrated to form an oscillator circuit, which is driven by the negative differential conductance property of a GTD. It is demonstrated that as the gate tunes the magnitude of the output conductance, the oscillator may be switched on and off, creating short RF pulses. The

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A supermacroporous cryogel bioreactor has been developed to culture hybridoma cells for long-term continuous production of monoclonal antibodies (mAb). Hybridoma clone M2139, secreting antibodies against J1 epitope (GERGAAGIAGPK; amino acids, 551-564) of collagen type II, are immobilized in the porous bed matrix of a cryogel column (10 mL bed volume). The cells got attached to the matrix within 48

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Immigrant mothers in Spain have a lower risk of delivering Low BirthWeight (LBW) babies in comparison to Spaniards (LBW paradox). This study aimed at revisiting this finding by applying a model-based threshold as an alternative to the conventional definition of LBW.

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Breathlessness is common in the general population. Existing data were obtained primarily with the uni-dimensional modified Medical Research Council breathlessness scale (mMRC) that does not assess intensities of unpleasantness nor physical, emotional and affective dimensions. The aim of this research was to determine the prevalence and intensity of these dimensions of breathlessness in elderly ma

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Nocturnal hypoglycemia is a common and potentially very dangerous condition facing persons with insulin-treated diabetes. To reduce the risk of going low while sleeping, many patient wilfully elevate their glucose level before bedtime, thereby also eroding the conditions for a sound glucose control for the next day. Recent advances in sensor technology allow for real-time frequent monitoring of th

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he fictitious crack model is extended so that it includes the effect of crack shearing. By the introduction of the so-called equivalent length, it is possible to establish a smeared version of the fictitious crack model. The equivalent length is a purely geometrical quantity that depends entirely on the size and form of the element and on the crack direction. A realistic modeling of crack shearing

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A strategy for nuclear fuel bundle design optimization in boiling water reactors(BWRs), using a simplex method, is presented and examined. The objective of the study is to see how an automatic optimization scheme can create nuclear designs for use in BWR fuel bundles and how the scheme can be improved. Challenges with applying linear simplex optimization to non-linear bundle physics lie in approx

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A deracemization system for secondary alcohols was established after the analysis of individual steps and their compatibility in one pot. The chemical oxidation and bioreduction occurred in a sequential manner to yield 1-arylethanols and lineal aliphatic alcohols with excellent conversions and enantiomeric excess values. The oxidation step was performed by using 2,2,6,6-tetramethylpiperidin-1-oxyl

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Distribution and warehousing networks of Humanitarian Organizations has proven to be an area where cost reductions and shortened lead times can be achieved. Humanitarian organizations have also started pre-positioning goods in anticipation of disasters as a way to improve their disaster preparedness. Research in the area has, generally, been extensive but few articles have tried to incorporate the

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This thesis models fusion reactions for the production of superheavy elements using a fusion by diusion model. The work further develops the diusion model in Ref. [1], achieving signicant computational speedup. In the diffusion model, I demonstrate that the use of a Markov chain method in place of a Langevin random walk method decreases computational time signicantly, by at least two orders of mag

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Association for computer aided genealogy research of Sweden(DIS) is investigating the possibility of a nationwide genealogical database (RGD) of Sweden's historical population. The finished database should contain basic information about individuals' names, birth, marriage, death, and individuals' relationships such as father, mother, husband/wife and children. This will make up a kind

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The balancing act of an inverted pendulum with a robotic manipulator is a classical benchmark for testing modern control strategies in conjunction with fast sensor-guided movements. From the control design perspective, it presents a challenging and difficult problem as the system is open-loop unstable and includes nonlinear effects in the actuators, such as friction, backlash, and elasticity. In a

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The durability of a road is among other factors dependent on the affinity between stones in the top layer and bitumen that holds the stones together. Poor adherence will cause stones to detach from the surface of the road more easily. The rolling bottle method is the standard way to determine the affinity between stones and bitumen. In this test a number of stones covered in bitumen are put in a r

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A new laminar flamelet model is presented for Large Eddy Simulation ( LES) of premixed turbulent combustion. The model uses a marker field S+ to capture the flame. Compared to previous work on marker fields, a modification was introduced to simplify the boundary conditions. Although the scalar S+ is smooth in space, it allows describing steep flame fronts. The S+ equation captures the laminar or t

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Structural best management practices (BMPs) are now commonplace for stormwater management in new suburban developments; however, their installation in older central areas is limited. Here, the effect of disconnecting impervious areas from a combined sewer in favour of a new open stormwater system is investigated. The site, an inner city suburb of Malmo, Sweden, consists of council offices and apar

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The aim of this study was to develop a simple experimental methodology and to develop a mechanistic model to characterize the release mechanism from pellets developing cracks during the release process with special focus on osmotic effects. The release of remoxipride from pellets coated with an ethyl cellulose film was chosen as a case study. Dose release experiments at different bulk osmotic pres