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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 193191 sökträffar

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Insects constitute a very important part of the global ecosystem and include pollinators, disease vectors, and agricultural pests, all with pivotal influence on society. Monitoring and control of such insects has high priority, and automatic systems are highly desirable. While capture and analysis by biologists constitute the gold standard in insect identification, optical and laser techniques hav

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An approach involving rational structural elaboration of the biologically active natural product diindolylmethane (DIM) with the incorporation of aminophosphonate and urea moieties toward the discovery of potent anticancer agents was considered. A four-step approach for the synthesis of DIM aminophosphonate and urea derivatives was established. These novel compounds showed potent anticancer activi

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Melatonin is a powerful antioxidant and a synchronizer of many physiological processes. Alteration of the melatonin pathway has been reported in circadian disorders, diabetes and autism spectrum disorders (ASD). However, very little is known about the genetic variability of melatonin receptors in humans. Here, we sequenced the melatonin receptor MTNR1A and MTNR1B, genes coding for MT1 and MT2 rece

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Linkage between behavioral states and neural activity is one of the most important challenges in neuroscience. The network activity patterns in the awake resting state and in the actively behaving state in rodents are not well understood, and a better tool for differentiating these states can provide insights on healthy brain functions and its alteration with disease. Therefore, we simultaneously

Hålls den glutenfria kosten efter celiakidiagnos? 2023

Det är många barn i TEDDY som utvecklat autoantikroppar mot vävnadstransglutaminas (TGA) och senare diagnosticerats med celiaki. Sjukdomen behandlas med glutenfri kost för resten av livet. Syftet med studien var att undersöka hur väl barnen kunde följa den glutenfria kosten.I TEDDY har 8 676 barn deltagit i studien från det att barnen var 3–4 månader gamla. Totalt har 6 868 barn screenats för TGA

https://www.teddy.lu.se/resultat-fran-teddy/alla-forskningsartiklar/celiaki/halls-den-glutenfria-kosten-efter-celiakidiagnos-2023 - 2026-07-11

From Global Challenges to Sustainable Career Choices

16 april 2026 14:00 till 15:00 | Workshop What will work look like in the future and what skills will matter most? In this interactive workshop, we explore global challenges shaping careers and invite you to reflect on how to find meaningful and sustainable work that connects your talents and interests with the world’s needs. Sustainability is changing how we think about work, careers, and the ski

https://www.lu.se/evenemang/global-challenges-sustainable-career-choices - 2026-07-12

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Purpose: The superior soft tissue contrast of magnetic resonance imaging (MRI) compared to computed tomography (CT) has urged the integration of MRI and elimination of CT in radiotherapy treatment (RT) for prostate. An intraprostatic gold fiducial marker (GFM) appears hyperintense on CT. On T2-weighted (T2w) MRI target delineation images, the GFM appear as a small signal void similar to calcificat

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Genomic manipulation of Yersinia ruckeri, a pathogen of salmonid fish species, is essential for understanding bacterial physiology and virulence. Here, we present a protocol for genomic recombineering in Y. ruckeri, a species reluctant to standard genomic engineering, using CRISPR Cas12a coupled with the λ Red system. We describe steps for identifying protospacer guides, preparing repair template

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We have synthesized and characterized a novel high affinity radioiodinated α1-adrenergic receptor photoaffinity probe, 4-amino-6,7-dimethoxy-2-[4-[5-(4-azido-3-[125I]iodophenyl)pentanoyl]-1-p iperazinyl] quinazoline. In the absence of light, this ligand binds with high affinity (K(D) = 130 pM) in a reversible and saturable manner to sites in rat hepatic plasma membranes. The binding is stereoselec

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AIMS/HYPOTHESIS: To date, the molecular function of most of the reported type 2 diabetes-associated loci remains unknown. The introduction or removal of cytosine-phosphate-guanine (CpG) dinucleotides, which are possible sites of DNA methylation, has been suggested as a potential mechanism through which single-nucleotide polymorphisms (SNPs) can affect gene function via epigenetics. The aim of this

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The porcine and human pathogen Streptococcus suis induces and degrades neutrophil extracellular traps (NETs) in vitro. In this study, we investigated the working hypothesis that NET degradation is mediated not only by the known secreted S. suis nuclease A (SsnA) but also by a so-far undescribed putative endonuclease A of S. suis (designated EndAsuis) homologous to the pneumococcal endonuclease A (

Changing spatialities and agency at Myanmar’s highest borderlands

13 maj 2025 15:15 till 17:00 | Föreläsning Open lecture with Karin Dean, senior researcher, Tallinn University Myanmar’s highest borderlands are defined by naturally connected but politically and geopolitically dissected vast mountainous spaces of the eastern Himalayas around the tri-junction of China, Myanmar and India. Their sweeping extent, but more so the politics and challenges of access allo

https://www.lu.se/evenemang/changing-spatialities-and-agency-myanmars-highest-borderlands - 2026-07-12