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The ability to sense and accommodate to an ever-changing environment is crucial for the survival of living organisms. Transient Receptor Potential (TRP) ion channels comprise a large superfamily of cation conducting membrane proteins that function as molecular sensors in diverse sensory processes including perception of light, taste, smell, sound, touch and temperature. The TRP Ankyrin 1 (TRPA1) i

Breathlessness is common in the general population. Existing data were obtained primarily with the uni-dimensional modified Medical Research Council breathlessness scale (mMRC) that does not assess intensities of unpleasantness nor physical, emotional and affective dimensions. The aim of this research was to determine the prevalence and intensity of these dimensions of breathlessness in elderly ma

X-ray phase-contrast imaging allows for non-invasive analysis in low-absorbing materials, such as soft tissue. Its application in medical or materials science has yet to be realized on a wider scale due to the requirements on the X-ray source, demanding high flux and small source size. Laser wakefield accelerators generate betatron X-rays fulfilling these criteria and can be suitable sources for p

Association for computer aided genealogy research of Sweden(DIS) is investigating the possibility of a nationwide genealogical database (RGD) of Sweden's historical population. The finished database should contain basic information about individuals' names, birth, marriage, death, and individuals' relationships such as father, mother, husband/wife and children. This will make up a kind

The balancing act of an inverted pendulum with a robotic manipulator is a classical benchmark for testing modern control strategies in conjunction with fast sensor-guided movements. From the control design perspective, it presents a challenging and difficult problem as the system is open-loop unstable and includes nonlinear effects in the actuators, such as friction, backlash, and elasticity. In a

A deracemization system for secondary alcohols was established after the analysis of individual steps and their compatibility in one pot. The chemical oxidation and bioreduction occurred in a sequential manner to yield 1-arylethanols and lineal aliphatic alcohols with excellent conversions and enantiomeric excess values. The oxidation step was performed by using 2,2,6,6-tetramethylpiperidin-1-oxyl

Saccadic eye movements provide important information about the neuron system at several levels. In recent years computer analysis of saccades has been adapted for use in clinical work. The most common detection methods do not always function without the user's control and aid. In the present paper a digital filter is described for the detection of saccades. This non-recursive filter unscrambles sa

Utilizing semiconductor nanowires for (opto)- electronics requires exact knowledge of their current−voltage properties. We report accurate on-top imaging and I−V characterization of individual as-grown nanowires, using a subnanometer resolution scanning tunneling microscope with no need for additional microscopy tools, thus allowing versatile application. We form Ohmic contacts to InP and InAs nan

Structural best management practices (BMPs) are now commonplace for stormwater management in new suburban developments; however, their installation in older central areas is limited. Here, the effect of disconnecting impervious areas from a combined sewer in favour of a new open stormwater system is investigated. The site, an inner city suburb of Malmo, Sweden, consists of council offices and apar

The aim of this study was to develop a simple experimental methodology and to develop a mechanistic model to characterize the release mechanism from pellets developing cracks during the release process with special focus on osmotic effects. The release of remoxipride from pellets coated with an ethyl cellulose film was chosen as a case study. Dose release experiments at different bulk osmotic pres

A new laminar flamelet model is presented for Large Eddy Simulation ( LES) of premixed turbulent combustion. The model uses a marker field S+ to capture the flame. Compared to previous work on marker fields, a modification was introduced to simplify the boundary conditions. Although the scalar S+ is smooth in space, it allows describing steep flame fronts. The S+ equation captures the laminar or t

The durability of a road is among other factors dependent on the affinity between stones in the top layer and bitumen that holds the stones together. Poor adherence will cause stones to detach from the surface of the road more easily. The rolling bottle method is the standard way to determine the affinity between stones and bitumen. In this test a number of stones covered in bitumen are put in a r

The purpose of this report is to investigate a branch and bound algorithm designed to construct monotone smoothing splines. The splines are defined as the solution of a minimization problem, where one wants to find a curve with non-negative derivative everywhere, that fits a data set consisting of points in the plane, while also being sufficiently smooth. The report describes the theory necessary

Distribution and warehousing networks of Humanitarian Organizations has proven to be an area where cost reductions and shortened lead times can be achieved. Humanitarian organizations have also started pre-positioning goods in anticipation of disasters as a way to improve their disaster preparedness. Research in the area has, generally, been extensive but few articles have tried to incorporate the