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G protein-coupled receptor 30 (GPR30) is a ubiquitously expressed receptor reported to bind and become activated by estrogen (17β-estradiol). However, the role of GPR30 as an estrogen receptor for rapid estrogenic signaling is not completely accepted, and controversies exist regarding the identity of the cognate ligand, signaling, and subcellular localization of the receptor. Expression of GPR30 i
Stimulation of rat adipocytes with insulin and isoproterenol results in serine phosphorylation and activation of the adipocyte cGMP-inhibited phosphodiesterase (cGI PDE), events believed to be important in the antilipolytic action of insulin (Degerman, E., Smith, C.J., Tornqvist, H., Vasta, V., Manganiello, V.C., and Belfrage, P. (1990) Proc. Natl. Acad. Sci. U.S.A. 87,533-537). Here we demonstrat
The recently discovered selective glomerular hypofiltration syndromes have increased interest in the actual elimination of molecules in the human kidney. In the present study, a novel human model was introduced to directly measure the single-pass renal elimination of molecules of increasing size. Plasma concentrations of urea, creatinine, C-peptide, insulin, pro-BNP, β2-microglobulin, cystatin C,
28 maj 2026 17:00 till 19:00 | Seminarium 17:00 Opening Annie Lindberg, Director of Skissernas Museum, welcomes guests.Introduction Marcus Rancken, Strategic Property Developer and Head of Art, and Lotta Mossum, Head of the Art Unit, introduce the collaboration between the Public Art Agency Sweden and Akademiska Hus.Background Moderators Robert Holmberg (Researcher and Senior Lecturer, Department
https://www.lu.se/evenemang/seminar-shaping-shared-spaces-public-art-between-idea-site-and-practice-kvparadis - 2026-07-10
Experimental studies are carried out to investigate the jet impingement heat transfer in crossflow by liquid crystal thermography (LCT). The aim is to assess the possibility of controlling heat transfer by using a rib. The crossflow Reynolds number spans from 80,000 to 160,000 and the velocity ratio ranges from 1.0 to 2.8. The results show that the presence of rib can significantly modify the heat
For photon fields, separate dose distribution kernels have been generated for charged particles produced in the first interaction, for single and multiple scattered photons, including bremsstrahlung and annihilation. These kernels are applied in absorbed dose calculations for radiotherapy treatment planning using a convolution technique. The vast amount of kernel data required for 3D calculations
Urinary Incontinence is a problem for many people which can give rise to both psychological and social issues. To their aid there are a range of incontinence products available in retail today. A customer concern is however possible malodor formation. Studies have shown that both urine and the bacterial flora can contribute to malodor but the impact of microbial behavior in incontinence products o
Background/aims: Acid–base status is important for understanding pathophysiology, making a diagnosis, planning effective treatment and monitoring progress of critically ill patients. Manual calculations are cumbersome, easily result in wrong conclusions. We wanted to develop an automated assessment of acid–base status. Methods: A simplified adaptive MATLAB script processing all available theory to
Affilierad forskare Kontaktinformation E-post: vitor [dot] souza [at] plog [dot] lth [dot] se Telefon: +46 46 222 41 11Organisation Förpackningslogistik Besöksadress: Sölvegatan 26, Lund Rumsnummer: 421 Hämtställe: 69 WebbplatsVitor Souzas profil i Lunds universitets forskningsportalAndra roller Postdoktor CIRCLE Affilierad forskare Centrum för handel och logistik (REAL) Gästlärare Institutionen f
https://www.real.lu.se/vitor-souza - 2026-07-09
Background The Chemotaxis inhibitory protein of Staphylococcus aureus (CHIPS) blocks the Complement fragment C5a receptor (C5aR) and formylated peptide receptor (FPR) and is thereby a potent inhibitor of neutrophil chemotaxis and activation of inflammatory responses. The majority of the healthy human population has antibodies against CHIPS that have been shown to interfere with its function in vit
The rapid spread of antibiotic resistance-currently one of the greatest threats to human health according to WHO-is to a large extent enabled by plasmid-mediated horizontal transfer of resistance genes. Rapid identification and characterization of plasmids is thus important both for individual clinical outcomes and for epidemiological monitoring of antibiotic resistance. Toward this aim, we have d
Human hair is laminar-fibrous tissue and an evolutionarily old keratinization product of follicle trichocytes. Studies on the hair proteome can give new insights into hair function and lead to the development of novel biomarkers for hair in health and disease. Human hair proteins were extracted by detergent and detergent-free techniques. We adopted a shotgun proteomics approach, which demonstrated
