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Popular Abstract in English All living things somehow communicate with each other. Cell-to-cell communication, or signalling, occurs on the molecular level, regulating the body’s activities and coordinating various cell actions and is thereby valuable for realizing cell as well as system functions. Errors in the cellular transferred information may induce diseases such as cancer and autoimmune disGlypicans are multifunctional cell surface heparan sulphate proteoglycans co-regulating numerous signalling pathways, and are thereby involved in the control of cellular division, differentiation, and morphogenesis. The heparan sulphate (HS) chains are responsible for many of those biological functions; nevertheless recent studies suggest functional roles for the glypican core proteins in mediatin

A model implemented in order to describe the electricity demand on hourly basis for the Nordic countries. The objective of this project is to use the demand data simulated from the model as input data in the price forecast model, EMPS model, at Vattenfall. The time horizon is 5 years, 6 years including the current year. After different models tried out, the final model is described by fundamental

This report will examine the reliability of calculation methods used for concrete structures in the serviceability limit state. A comparison between the different methods will be done, based on calculations of the reliability index for these methods. This comparison will be the base for a discussion about what norm that should be prefferd in different situations and what level of reliability the c

In the 20th century, Sweden distinguished itself as one of the most organized and participatory democracies in the world. But in the late 19th century the situation was much the opposite – Sweden had for Western Europe a low degree of suffrage, and low political participation. To explain the turnaround, this paper explores the evolution of a democratic political culture in the final third of the 1In the 20th century, Sweden distinguished itself as one of the most organized and participatory democracies in the world. But in the late 19th century the situation was much the opposite – Sweden had for Western Europe a low degree of suffrage, and low political participation. To explain the turnaround, this paper explores the evolution of a democratic political culture in the final third of the 1

The intention of this thesis is to explore how four self-defined BDSM practitioners describe and understand their practices. Furthermore, I want to explore if their point of view can help us to understand BDSM in other terms than violence and battery. The interviews are semi structured and were done through instant messaging. By using grounded theory method it turned up that the informants describ

People make sense of objects and events around them by classifying them into identifiable categories. The extent to which language affects this process has been the focus of a long-standing debate: Do different languages cause their speakers to behave differently? Here, we show that fluent German-English bilinguals categorize motion events according to the grammatical constraints of the language i

In my Ph. D. project, I study semantic change as it is described in the Swedish Acad-emy dictionary (SAOB). The starting point is five semantic labels that are established and highly frequent in the dictionary definitions, namely: bildlig (‘figurative’), oegent-lig (‘un-actual/non-factual’), överförd (‘transferred’), utvidgad (‘extended’) and all-männare användning (‘more general use’). These labe

LU Samverkan ingår i sektion Forskning, samverkan och innovation. Avdelningen samlar medarbetare med olika ämnesbakgrund och kompetens inom samverkan, projektledning och kommunikation för att stödja universitetet i utvecklingen av strategiska samarbeten och samverkansplattformar. Arbetet utförs på uppdrag av universitetsledningen. Avdelningen är en väg in till universitetet för regioner, kommuneLU Collaboration is a department within the University Administration’s Section for Research, Collaboration and Innovation. The department brings together employees with different disciplinary backgrounds and operational expertise in developing and managing projects and broader collaborative initiatives, as well as communicating the process and impact of this work to support the university in the

Using cyclic boundary conditions and LCAO basis allows one to reproduce both band and local properties of the electronic structure of a crystal. Electronic structure of a row of composite copper and lead crystalline oxides are studied within the CNDO approximation, and the local properties (atomic charges, bond orders, valencies) are analyzed. A comparison of the local properties of some high-Tc s

Purpose: The purpose of this document is threefold: (a) review the uses of the terms “vocal fatigue,” “vocal effort,” “vocal load,” and “vocal loading” (as found in the literature) in order to track the occurrence and the related evolution of research; (b) present a “linguistically modeled” definition of the same from the review of literature on the terms; and (c) propose conceptualized definition

We report on the characterization of the new I1011 beamline at the MAX-II storage ring, in the MAX-lab synchrotron radiation laboratory and give examples of first results. This beamline is using an Elliptically Polarizing Undulator source, producing soft x-rays of a variable polarization state. It delivers high flux and high brightness circularly polarized x-rays in the energy range 0.2 to 1.7 keV

Pathogenic mutations in DPAGT1 cause a rare type of a congenital disorder of glycosylation termed DPAGT1-CDG or, alternatively, a milder version with only myasthenia known as DPAGT1-CMS. Fourteen disease-causing mutations in 28 patients from 10 families have previously been reported to cause the systemic form, DPAGT1-CDG. We here report on another 11 patients from 8 families and add 10 new mutatio

Background: The aim of the study was to describe the technique of two-trocar laparoscopic appendectomy and compare the outcome between two- and three-trocar techniques in children. Methods: All children who underwent laparoscopic surgery for suspected appendicitis from 2006 to 2014 in a center for pediatric surgery were included in the study. Converted surgeries and patients with appendiceal absce

Most complex diseases have well-established genetic and non-genetic risk factors. In some instances, these risk factors are likely to interact, whereby their joint effects convey a level of risk that is either significantly more or less than the sum of these risks. Characterizing these gene-environment interactions may help elucidate the biology of complex diseases, as well as to guide strategies

Tapering is a mode of operation of insertion devices that allows the users to perform scanning in a range of photon energies. NanoMAX, BioMAX and BALDER are all beamlines of the 3 GeV MAX IV storage ring and will provide this special mode of operation for their users. In this thesis, the spectra of NanoMAX and BioMAX while operating with tapering were studied and feed forward tables that cancel ou

One of the toughest challenges for the international community is to justify military interventions in sovereign states. Echoing in terms of post-colonialism, underlying interest and power domination, military interventions must be argued for and legitimized in order to gain support from both public and institutional opinion. This is even more essential in our modern era with its rapid and unimped

This dissertation deals with the effects of nuclear structure on the α-decay properties, and on the fission-yielddistributions from the decay of heavy nuclei. The nuclear-structure and decay properties of superheavynuclei is one of the central topics for investigation. α decay is treated in a microscopic approach employingSkyrme-Hartree-Fock-Bogoliubov wave functions to describe the formation of aThis dissertation deals with the effects of nuclear structure on the α-decay properties, and on the fission-yielddistributions from the decay of heavy nuclei. The nuclear-structure and decay properties of superheavynuclei is one of the central topics for investigation. α decay is treated in a microscopic approach employingSkyrme-Hartree-Fock-Bogoliubov wave functions to describe the formation of a

The purpose of the present paper is to describe and discuss the concept of hunter mode, as introduced by Meidell (2022) in her autobiographical description of anorexia nervosa. Hunter mode is a sought-after state that is reached through self-starvation and that transforms a person's experiences into a crystal-clear perception and a sense of vitality. Although partly touched upon already by Hilde B