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A complex reaction mechanism of oxidation of the anti-tubercular prodrug isoniazid (isonicotinic hydrazide, INH) by [IrCl6]2− as a model for redox processes of such drugs in biological systems has been studied in aqueous solution as a function of pH between 0 and 8.5. Similar experiments have been performed with its isomer nicotinic hydrazide (NH). All reactions are overall second-order, first-ord

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This report presents an integrated simulation-based approach to study the on-site production of concrete frameworks by considering the multiple effects of weather on work task productivity and concrete curing process. The suggested approach enable to systematically study how different weather conditions and the use of climate-improved concrete in combination with different methods to shield concre

Forskargruppen för systemisk skleros, Lund

Systemisk skleros, SSc, är en ovanlig reumatologisk sjukdom där immunologisk aktivering leder till kärlskada och fibros i hud och inre organ. Hälften av patienterna avlider av komplikationer från hjärta eller lungor, ofta fibros i lungor eller pulmonell arteriell hypertension (PAH). Projekten rör kartläggning av tidiga mekanismer kring patogenes och biomarkörer för tidig diagnos och monitorering aSystemic sclerosis, SSc, is a rare rheumatologic disease where immun activation leads to vascular damage and fibrosis in skin and internal organs. Half of the population will die from complications from heart or lungs, mostly lung fibrosis or pulmonary arterial hypertension (PAH). Our projects aim at early pathogenic mechanisms and biomarkers for early diagnosis and to monitor the disease and the