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Machine learning is increasingly used as a computing paradigm in cartographic research. In this extended editorial, we provide some background of the papers in the CaGIS special issue Machine Learning in Cartography with a special focus on pattern recognition in maps, cartographic generalization, style transfer, and map labeling. In addition, the paper includes a discussion about map encodings for
An unbroken digital data flow would save substantial resources in the built environment process. In this study, which is part of a larger Swedish project, data delivery specifications and methods to integrate BIM and geodata are developed and tested with the aim to facilitate such an unbroken data flow. The main focus areas of the study are: (1) specifications that enables building permission appl
Climate change and eutrophication are two environmental threats that can alter the structure of freshwater ecosystems and their service functions, but we know little about how ecosystem structure and function will evolve in future scenarios of climate warming. Therefore, we created different experimental climate scenarios, including present-day conditions, a 3.0 °C increase in mean temperature, an
We derive and validate an analytical model that describes the migration of Raman scattered photons in two-layer diffusive media, based on the diffusion equation in the time domain. The model is derived under a heuristic approximation that background optical properties are identical on the excitation and Raman emission wavelengths. Methods for the reconstruction of two-layer Raman spectra have been
BackgroundVentral midbrain (VM) dopaminergic progenitor cells derived from human pluripotent stem cells have the potential to replace endogenously lost dopamine neurons and are currently in preclinical and clinical development for treatment of Parkinson’s Disease (PD). However, one main challenge in the quality control of the cells is that rostral and caudal VM progenitors are extremely similar tr
BACKGROUND: There are important unmet clinical needs to develop cell enrichment technologies to enable unbiased label-free isolation of both single cell and clusters of circulating tumor cells (CTCs) manifesting heterogeneous lineage specificity. Here, we report a pilot study based on microfluidic acoustophoresis enrichment of CTCs using the CellSearch CTC assay as a reference modality.METHODS: Ac
The generation of maps in real-time web-services introduces challenges concerning map legibility. As these services lack the important input of a traditional cartographer, analytical measures of the legibility are called for. The aim of this study was to develop such legibility measures, and to evaluate them with the help of expert users. Measures of the amount of information, spatial distribution
The proto-oncogene SKI is highly expressed in human myeloid leukemia and also in murine hematopoietic stem cells. However, its operative relevance in these cells remains elusive. We have over-expressed SKI to define its intrinsic role in hematopoiesis and myeloid neoplasms, which resulted in a robust competitive advantage upon transplantation, a complete dominance of the stem and progenitor compar
Attempts to use colloid science concepts to better understand the dynamic properties of concentrated or crowded protein solutions are challenging due to the fact that globular proteins generally have heterogeneous surfaces that result in anisotropic or patchy contributions to their interaction potential. This is particularly difficult when targeting non-equilibrium transitions such as glass and ge
Sommaren 2018 var ett rekordvarmt år, och en markant ökning på solkurvor konstaterades av Trafikverket. Det finns flera orsaker till varför en solkurva uppstår, förutom den ökade temperaturen. När en solkurva bildas dras slutsatsen i många fall att anledningen endast är hög temperatur och vidare undersökningar utesluts direkt. Detta examensarbete består till stor del av en litteraturstudie som bThe summer of 2018 was a hot year, a significant increase of sun curves was observed by Trafikverket. There are several reasons why a sun curve occurs, in addition to the high temperature. When a sun curve is formed, the conclusion is drawn in many cases that the reason was heat and no further investigations are made. The project consists a literature study that explains the physical theory, fac
This chapter reviews the historical development of the regulation of waste and chemicals in both international law and European Union (EU) law after the 1972 Stockholm Conference as well as some of the subsequent trends and themes. It also highlights the relevant interactions between EU and international law on these issues. The chapter ends with a discussion of how the regulatory frameworks relat
Women are born with thousands of ovarian follicles, yet less than 1% will ovulate a mature oocyte. What distinguishes the 99% of follicles destined for demise from the rare 1% that succeed? Here, we leveraged a unique clinical opportunity, paired follicular fluid samples from small antral follicles containing either a viable or an atretic oocyte within the same patients, to uncover the proteomic d
