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The resistance of human immunodeficiency virus type 1 (HIV-1) to antibody-mediated immunity often prevents the detection of antibodies that neutralize primary isolates of HIV-1. However, conventional assays for antibody functions other than neutralization are suboptimal. Current methods for measuring the killing of virus-infected cells by antibody-dependent cell-mediated cytotoxicity (ADCC) are li

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Three large-scale Echovirus (E) epidemics (E4,E16,E30), each differently associated to the acute development of diabetes related autoantibodies, have been documented in Cuba. The prevalence of islet cell autoantibodies was moderate during the E4 epidemic but high in the E16 and E30 epidemic. The aim of this study was to evaluate the effect of epidemic strains of echovirus on beta-cell lysis, beta-

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The transition quadrupole moments. Q(t), of four weakly populated collective bands up to spin similar to 65h in Er-157,Er-158 have been measured to be similar to II eb demonstrating that these sequences are associated with large deformations. However, the data are inconsistent with calculated values from cranked Nilsson-Strutinsky calculations that predict the lowest energy triaxial shape to be as

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This paper presents two circuits, a complete 1.5 V 28 GHz SiGe beam steering PLL and a standalone 28 GHz QVCO with I/Q phase imbalance detection and compensation. The circuits were designed in a SiGe process with f T = 200 GHz. The PLL is intended to be used for beam steering in an 81–86 GHz E-band transmitter. Phase control is implemented by DC current injection at the output of a Gilbert archite

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ABSTRACT: BACKGROUND: The conditions for steam pretreatment of sugar cane bagasse and leaves were studied using CO2 as an impregnating agent. The following conditions were investigated: time (5 to 15 min) and temperature (190 to 220 degrees C). The pretreatment was assessed in terms of glucose and xylose yields after enzymatic hydrolysis and inhibitor formation (furfural and hydroxymethylfurfural)

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Background: Functional and morphological changes of the heart influence blood flow patterns. Therefore, flow patterns may carry diagnostic and prognostic information. Three-dimensional, time-resolved, three-directional phase contrast cardiovascular magnetic resonance (4D PC-CMR) can image flow patterns with unique detail, and using new flow visualization methods may lead to new insights. The aim o

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The ATLAS detector at the LHC is used to search for high-mass states, such as heavy charged gauge bosons (W'), decaying to a charged lepton (electron or muon) and a neutrino. Results are presented based on the analysis of pp collisions at a center-of-mass energy of 7 TeV corresponding to an integrated luminosity of 4.7 fb(-1). No excess beyond Standard Model expectations is observed. A W' with Seq

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Elevated cystatin C in blood reflects impaired glomerular filtration rate (GFR), but current cystatin C assays, based on polyclonal antibodies and immunoturbidimetric or nephelometric detection, have several limitations. We evaluated a new immunoassay based on monoclonal antibodies in samples from patients with and without chronic kidney disease (CKD). The study enrolled 170 men without known CKD

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Pyrazinamide (PZA) is a potent first-line agent for the treatment of tuberculosis (TB) with activity also against a significant part of drug-resistant Mycobacterium tuberculosis strains. Since PZA is active only at acid pH, testing for susceptibility to PZA is difficult and insufficiently reproducible. The recommended critical concentration for PZA susceptibility (MIC, 100 mg/liter) used in the Ba

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Background: The intervention; "Continuum of Care for Frail Older People", was designed to create an integrated continuum of care from the hospital emergency department through the hospital and back to the older person's own home. The aim of this study is to evaluate the effects of the intervention on functional ability in terms of activities of daily living (ADL). Methods: The study is a non-blind

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Previous prevalence rates of non-suicidal self-injury(NSSI) in adolescents have varied considerably. In the present cross-sectional study, prevalence rates, characteristics and functions of NSSI were assessed in a large randomized community sample consisting of 3,060 (50.5 % female) Swedish adolescents aged 15–17 years. The suggested criteria for NSSI disorder in the Diagnostic and Statistical Man

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A search for new phenomena in events featuring a high energy jet and large missing transverse momentum in proton-proton collisions at root s = 7 TeV is presented using a dataset corresponding to an integrated luminosity of 33 pb(-1) recorded with the ATLAS detector at the Large Hadron Collider. The number of observed events is consistent with the Standard Model prediction. This result is interpret

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The thesis attempts to assess the role of the OECD Commentaries in tax treaty interpretation process concluded between Non-OECD and OECD states. In order to reach the goal of the thesis the thesis discusses the legal status of the OECD Commentaries under public international law, in particular the interrelation of the Commentaries with the Articles of 31 and 32 of the Vienna Convention. The thesis

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The main goal of this thesis is to determine to what degree can there be observed indications for an overvaluation of Internet companies, which in turn may lead to the next asset price bubble in the Internet industry. By conducting an ex-ante analysis, the current study sets out to add additional knowledge in regards to whether and how well the emergence of a bubble can be determined in advance. T

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OECD and other organizations argues in favor of the implementation of regulations on conflict of interest for higher civil servants and public officials, often including quarantine time for these employees when changing jobs. They do this with the argument that it will increase the population’s confidence in their governments, which again is claimed to be a cornerstone of the functioning of the st

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The purpose of this study is twofold. Firstly, it aims to contribute to research by creating an understanding of how partners are selected in practice by an open innovation community. Secondly, it aims to contribute to research by building on the theories of causation and effectuation, as well as bricolage - a novel approach to partnership selection. We took an interpretive epistemological stance,

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Some practices are seen as so serious and damaging to competition that they are presumed to have restrictive effects on competition. Having a category of restrictions that are forbidden benefits both companies, as it creates legal certainty, and the Commission which would not not have to go through a burdensome investigation. In recent decades, the interpretation of restriction by object has cause

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Varför väljer utbildare inom FM de utbildningsmetoder de väljer? Vilka faktorer påverkar? Skiljer sig FMs utbildningsmetoder från skolans utbildningsmetoder? Denna studie penetrerar frågorna ur före detta värnpliktigas synvinkel. En litteraturstudie redovisar en jämförelse mellan utbildningsmetoder inom olika utbildningar, inte bara inom skolans värld. En kvantitativ och kvalitativ studie redovisa

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Despite the great significance of geomorphologic-environmental data in different disciplines, there are sundry problems in relation to availability, accessibility and their applicability. Primarily the problems dealing with these data were investigated and then technical solutions to remove each of the above problems and how to manage geomorphologic-enviromnental data were suggested. The solution