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From the early 1990s and onwards the use of debt relief as a method of providing development assistance has become increasingly popular, especially since the launch of the HIPC initiative in 1996. This thesis aims to investigate the general theoretical and empirical support of the growth enhancing properties of debt relief with regard to low income countries. Focus is put on evaluating the harmful
For the first time, Pulsed Field Gradient-Nuclear Magnetic Resonance, a powerful noninvasive tool for studying the dynamics and structure of complex-gels, has been used to measure diffusion of probe molecules in aqueous solutions/gels of noncommercial purified pig gastric mucin (PGM), in a concentration range up to 5 wt%. Complementary data were obtained from rheology measurements. The combination
Palaeomagnetic analyses were conducted on two varved lake-sediment sequences in northern Sweden. The magnetic properties of the sediment sequences are dominated by stable single-domain magnetite with characteristics typical of bacterial magnetosomes. Alternating field demagnetization measurements indicate that the single-domain magnetite is the dominant carrier of a stable natural remanent magneti
A method of removing radiolabeled monoclonal antibodies (mAbs) from blood using a device external to the body, termed extracorporeal affinity-adsorption (EAA), is being evaluated as a means of decreasing irradiation of noncancerous tissues in therapy protocols. The EAA device uses an avidin column to capture biotinylated-radiolabeled mAbs from circulated blood. In this investigation, three trifunc
Surveys of prescribing patterns in both hospitals and primary care have usually shown delays in translating the evidence from clinical trials of pharmacological agents into clinical practice, thereby denying patients with heart failure (HF) the benefits of drug treatments proven to improve well-being and prolong life. This may be due to unfamiliarity with the evidence-base for these therapies, the
Screening for gene copy-number alterations (CNAs) has improved by applying genome-wide microarrays, where SNP arrays also allow analysis of loss of heterozygozity (LOH). We here analyzed 10 chronic lymphocytic leukemia (CLL) samples using four different high-resolution platforms: BAC arrays (32K), oligonucleotide arrays (185K, Agilent), and two SNP arrays (250K, Affymetrix and 317K, Illumina). Cro
Transverse single-spin asymmetries to probe the transverse-spin structure of the proton have been measured for neutral pions and nonidentified charged hadrons from polarized proton-proton collisions at midrapidity and root s = 200 GeV. The data cover a transverse momentum (pT) range 1.0-5.0 GeV/c for neutral pions and 0.5-5.0 GeV/c for charged hadrons, at a Feynman-x value of approximately zero. T
Human islet amyloid polypeptide (hIAPP), a pancreatic islet protein of 37 amino acids, is the main component of islet amyloid, seen at autopsy in patients with type 2 diabetes mellitus (DM2). To investigate the roles of hIAPP and islet amyloid in DM2, we generated transgenic mice expressing hIAPP in their islet beta cells. In this study, we found that after a long-term, high-fat diet challenge isl
By using an integrated dynamic model we are able to reconstruct the supply and gold price of the past (1920-2010) and this is used to predict the future supply of gold to the market and to make a forecast of the goldprice 2010-2100. The model was validated against field data for the period 1920-2010 and it performs well. The model GOLD is implemented in the STELLA® software and the model described
This thesis is a summary of six papers which concern synthesis of optically active bicyclo[2.2.2]octane derivatives. The derivatives prepared are important building blocks in a study towards a possible replacement of the diterpenoidic part of taxol, (baccatin III), so as to construct a taxol mimic. Some of the derivatives have also been developed into new bidentate ligands. TitaniumIV complexes of
Popular Abstract in Swedish Värmebehandling av livmoderslemhinnan med ballongkateter - en ny metod att behandla rikliga mensblödningar. Mera än 11% av svenska kvinnor besväras av rikliga menstruationer (menorrhagi). När läkemedelsbehandling mot menorrhagi inte hjälper kan livmodern opereras bort. Varje år, i Sverige, opereras livmodern bort hos 4-5000 kvinnor på grund av rikliga mensblödningar. DThermal endometrial destruction by means of a silicone balloon catheter is a new form of treatment for menorrhagia aimed at reducing menstrual blood loss. The purpose of the present work was to study, experimentally, the thermal effects on and the thermal conductivity of uterine tissue, to obtain a basis for the estimation of optimal treatment conditions by means of numerical analyses using a comp
The growing interest in sustainable development indicators (SDI) has resulted in the development and application of various SDI frameworks in the past two decades. Identification and selection of “right” indicators with such frameworks are essential, in the sense that, it is the information from these indicators that will help policy and decision makers to better understand the efficiency, effecti
A positive and innovative organizational climate is of great importance in order to manage and adapt to change. Such a climate seldom evolves in organizations closely governed by rules and regulations. Because of ongoing organizational and technical changes within the Swedish Air Navigation Services Provider, a study concerning the organizational climate for changes and innovations was conducted t
Popular Abstract in Swedish Målsättningen med avhandlingen är att analysera vilken roll småskaligt entreprenörskap som alternativ överlevnadsstrategi har spelat i Sierra Leone under den ekonomiska kris som drabbade landet efter självständighet på 1960-talet. Avhandlingen baseras på nätverksteori, snowball metod och det empiriska underlaget utgörs av en studie av utvecklingen i Sierra Leone, med avSierra Leone is a small country with rich mineral resources such as diamonds, bauxite, gold and iron ore. Other resources include fishing, forestry and fertile agricultural land, which enable people to farm without any sophisticated methods of mechanization. Nevertheless, with all its wealth in resources, the country is relatively poor and is one of the least developed countries in the Sub-Saharan
This thesis aims to reconstruct and explain variations in storm activity, humidity, vegetation composition and land cover in south-west Sweden during the past 6500 years. Two ombrotrophic bogs, Store Mosse and Undarsmosse, situated on the coastal plain of Halland, were selected for this purpose. The coastal plain of Halland is positioned in the cyclone path and is therefore particularly sensitive
Pharmacological experiments were carried out on isolated basilar arteries (BA) from the brain vasculature of guinea-pig and rat in order to characterize post-junctional serotonergic receptors mediating contraction by the use of selective agonists and antagonists. The sensitivity to 5-HT was higher, but the intrinsic activity lower, in guinea-pig compared to rat vessels. The contractile potency of
