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Pre-diagnostic meat and fibre intakes in relation to colorectal cancer survival in the European Prospective Investigation into Cancer and Nutrition

Improvements in colorectal cancer (CRC) detection and treatment have led to greater numbers of CRC survivors, for whom there is limited evidence on which to provide dietary guidelines to improve survival outcomes. Higher intake of red and processed meat and lower intake of fibre are associated with greater risk of developing CRC, but there is limited evidence regarding associations with survival a

Design of an AI Support for Diagnosis of Dyspneic Adults at Time of Triage in the Emergency Department

We created an AI support for diagnosis in dyspneic adults at time of triage in the emergency department.Complete data from an entire regional health care system was analyzed, to find AI-derived, unknown, important diagnostic predictors. Most important were prior diagnoses of heart failure or COPD, daily smoking, atrial fibrillation/flutter, life difficulties and maternal care.Sensitivity for AHF,

Dual-Band Infrared Scheimpflug Lidar Reveals Insect Activity in a Tropical Cloud Forest

We describe an entomological dual-band 808 and 980 nm lidar system which has been implemented in a tropical cloud forest (Ecuador). The system was successfully tested at a sample rate of 5 kHz in a cloud forest during challenging foggy conditions (extinction coefficients up to 20 km–1). At times, the backscattered signal could be retrieved from a distance of 2.929 km. We present insect and bat obs

A Sound Approach Toward a Mobility Aid for Blind and Low-Vision Individuals

Det finns runt 100 000 blinda och kraftigt synnedsatta individer (BKSI:er) i Sverige. Sådan synnedsättning leder till en kraftigt minskad förmåga för självständig förflyttning och lägre livskvalité, med ökad risk för arbetslöshet, trafikolyckor, en stillasittande livsstil och depression. Hälften av alla käpp- och hundanvändare är med om en huvudkollision årligen, och drygt var tredje för en fallolReduced independent mobility of blind and low-vision individuals (BLVIs) cause considerable societal cost, burden on relatives, and reduced quality of life for the individuals, including increased anxiety, depression symptoms, need of assistance, risk of falls, and mortality. Despite the numerous electronic travel aids proposed since at least the 1940’s, along with ever-advancing technology, the m

Solar heating may explain extreme diel flight altitude changes in migrating birds

Great reed warblers, Acrocephalus arundinaceus,1 and great snipes, Gallinago media,2 exhibit a diel cycle in flight altitudes—flying much higher during the day than the night—when performing migratory flights covering both night and day. One hypothesis proposed to explain this behavior is that the birds face additional heating by solar radiation during daytime and hence must climb to very high, an

Missed Evaporation from Atmospherically Relevant Inorganic Mixtures Confounds Experimental Aerosol Studies

Sea salt aerosol particles are highly abundant in the atmosphere and play important roles in the global radiative balance. After influence from continental air, they are typically composed of Na+, Cl-, NH4+, and SO42- and organics. Analogous particle systems are often studied in laboratory settings by atomizing and drying particles from a solution. Here, we present evidence that such laboratory st

Nasal polyposis is a risk factor for nonadherence to CPAP treatment in sleep apnea : the population-based DISCOVERY study

STUDY OBJECTIVES: The aim was to evaluate nasal polyposis as a risk factor for nonadherence to continuous positive airway pressure (CPAP) treatment in patients with obstructive sleep apnea (OSA). METHODS: This was a population-based, longitudinal analysis of patients starting CPAP treatment for OSA in the Swedish quality registry Swedevox between 2010 and 2018. Data were cross-linked with national

Arbetsminnesförmåga hos klienter med missbruk i kombination med ADHD eller schizofreni

Senaste årens forskning visar intressanta likheter mellan diagnosgrupperna ADHD och schizofreni gällande kognitiva nedsättningar, framförallt i form av brister i arbetsminnet. Trots att missbruk är vanligt i dessa diagnosgrupper saknas forskning på huruvida dessa samband är giltiga även vid en komorbid missbruksdiagnos. Syftet med studien var därför att undersöka hur arbetsminnesförmågan ser ut fö

Eyes in the sky, Polisens användning av drönare och dess undantag från upplysningsplikten.

Swedish camera surveillance legislation has since 1977 contained requirements for permits, a consideration of the involved interests, and a duty to inform the surveilled. This applies to both authorities and citizens alike. The exceptions to these obligations have been few and restrictive. Over the years, surveillance legislation has been modernized to keep up with technological developments and p

The Game Changers that are changed by the Game (Entrepreneurs’ personal characteristics and learnings from failure)

Abstract Problem: While it has been extensively studied which personal characteristics enhance entrepreneurial learning from failure, the mechanisms of how those characteristics contribute to entrepreneurial learning process has not yet been fully understood. Aim: Through a comprehensive model, this research aims to explore how different personal characteristics influence the different stages o

“CP” ELLER “FUNKTIONSVARIERAD” - En kritisk diskursanalys om framställningen av personer med funktionshinder i svenska dags och kvällstidningar

Den problemformulering som ligger till grund för denna uppsats kretsar kring den stereotypiska bild som ofta blir central när vi talar om personer med funktionshinder. Studiens problemformulering grundas även på den ledande roll som media har för individers uppfattning av verkligheten och etablering av normer. Syftet med studien har således varit att studera hur personer med funktionshinder framst

Exploring the Functional Landscape of the p53 Regulatory Domain : The Stabilizing Role of Post-Translational Modifications

This study focuses on the intrinsically disordered regulatory domain of p53 and the impact of post-translational modifications. Through fully atomistic explicit water molecular dynamics simulations, we show the wealth of information and detailed understanding that can be obtained by varying the number of phosphorylated amino acids and implementing a restriction in the conformational entropy of the

Single-cell multiomics of human fetal hematopoiesis define a developmental-specific population and a fetal signature

Knowledge of human fetal blood development and how it differs from adult blood is highly relevant to our understanding of congenital blood and immune disorders and childhood leukemia, of which the latter can originate in utero. Blood formation occurs in waves that overlap in time and space, adding to heterogeneity, which necessitates single-cell approaches. Here, a combined single-cell immunopheno

HIV-2 mediated effects on target and bystander cells induce plasma proteome remodeling

Despite low or undetectable plasma viral load, people living with HIV-2 (PLWH2) typically progress toward AIDS. The driving forces behind HIV-2 disease progression and the role of viremia are still not known, but low-level replication in tissues is believed to play a role. To investigate the impact of viremic and aviremic HIV-2 infection on target and bystander cell pathology, we used data-indepen

Sociodemographic characteristics and COVID-19 testing rates : spatiotemporal patterns and impact of test accessibility in Sweden

BACKGROUND: Diagnostic testing is essential for disease surveillance and test-trace-isolate efforts. We aimed to investigate if residential area sociodemographic characteristics and test accessibility were associated with Coronavirus Disease 2019 (COVID-19) testing rates.METHODS: We included 426 224 patient-initiated COVID-19 polymerase chain reaction tests from Uppsala County in Sweden from 24 Ju

Diabetic status and the performances of creatinine- and cystatin C–based eGFR equations

Background. The estimation of glomerular filtration rate (GFR) is one tool to detect renal disease. The most used biomarker remains serum creatinine and the European Kidney Function Consortium (EKFCcrea ) equation is the most validated in Europe. More recently, cystatin C has been proposed as a biomarker. We studied the performances of the EKFC equations in a large cohort of subjects according to

Discordant Results Between Creatinine- and Cystatin C-based Equations for Estimating GFR

Introduction: Discordant results between cystatin C and creatinine in estimating glomerular filtration rate (GFR) are an important medical issue. However, the equation that should be used when GFR estimates are discordant remains unclear. Methods: This cross-sectional analysis included 15,485 participants with GFR measured by the clearance of an exogenous marker, serum creatinine, and cystatin C.

Effects of short-term multi-pollutant exposure on the oxidative stress status of captive songbirds

The human influence on Earth's ecosystems is omnipresent. Artificial light at night (ALAN), anthropogenic noise, and air pollution are inherent features of human activities and infrastructure and pose novel environmental challenges to urban-dwelling wildlife. So far, most of the studies investigating the impacts of exposure to urban pollutants on animals have either investigated the effects of urb