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Enhancing mitochondrial function in vivo rescues MDS-like anemia induced by pRb deficiency

Erythropoiesis is intimately coupled to cell division, and deletion of the cell cycle regulator retinoblastoma protein (pRb) causes anemia in mice. Erythroid-specific deletion of pRb has been found to result in inefficient erythropoiesis because of deregulated coordination of cell cycle exit and mitochondrial biogenesis. However, the pathophysiology remains to be fully described, and further chara

Exchange out brochure ht15 sv

Korea University Studera utomlands SamhällSvetenSkapliga fakulteten Dina möjligheter Som student vid Lunds universitet har du goda möjligheter att studera utomlands vid ett av våra många partner-universitet. Varje år reser ett stort antal samhällsvetarstudenter iväg på utbytesstudier. Utlandsstudier ger kunskap, vänner och minnen för livet och värdefulla erfarenheter som är till stora nytta när du

https://www.keg.lu.se/sites/keg.lu.se/files/exchange_out_brochure_ht15_sv.pdf - 2026-06-01

Tradslingan

Microsoft Word - Trädslingan.docx   1   Trädslingan i Botaniska trädgården     I  södra  delen  av  Botaniska  trädgården  har  vi  samlat  några  vanliga  svenska   träd  och  försett  dem  med  faktaskyltar.  Här  kan  man  arbeta  med  att  lära  sig   känna  igen  träden  på  deras  knoppar  och  löv.               Så  här  kan  man  jobba  med  trädslingan     • Tryck  ut  kartor  över  trädg

https://www.botan.lu.se/sites/botan.lu.se/files/tradslingan.pdf - 2026-06-01

Kompetensförsörjningsplan Juridiska Fakulteten JFS SLUTLIG 2019-12-11

2019-12-11 Dnr STYR 2019/1747 Juridiska fakultetens kompetensförsörjningsplan 2020–2022 Juridiska fakultetens strategiska plan omfattar perioden 2018–2026, och bygger på den strategiska planen för Lunds universitet för samma period. Fakultetens strategiska plan kompletteras av treåriga handlingsplaner av ett mer operativt slag med tydligt uppsatta och uppföljningsbara mål och åtgärder. Det handlar

https://www.law.lu.se/sites/law.lu.se/files/2023-09/Kompetensf%C3%B6rs%C3%B6rjningsplan%20Juridiska%20fakulteten%20JFS%20SLUTLIG%202019-12-11.pdf - 2026-06-01

Eckdahl literature review

Boreal Forests and the Effects of Fire in a Changing Climate First Year Review Department of Physical Geography and Ecosystem Science Lund University Johan Eckdahl Supervisors: Dan Metcalfe, Jeppe Kristensen November 2, 2020 Contents 1 Introduction 1 2 The Boreal Forests 3 2.1 Community Structure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2.1.1 Above ground . . . . . . . . . . .

https://www.nateko.lu.se/sv/sites/nateko.lu.se.sv/files/eckdahl_literature_review.pdf - 2026-06-01

COSB60 Course Outline 2024.8.27

1 COSB60: Contemporary Korean Society, 7.5 Credits Fall Semester 2024 2024-10-02 – 2024-12-03 Course Director: Youngeun Koo E-mail: youngeun.koo@ace.lu.se Course Outline (as of 27 August 2024; subject to further change) COURSE CONTENT The course provides students with a basic understanding of key issues in contemporary Korean society. It focuses on post-Cold War Korea. The course covers topics suc

https://www.ace.lu.se/sites/ace.lu.se/files/2024-08/COSB60_Course%20Outline_2024.8.27.pdf - 2026-06-01

Minnesanteckningar fran eds nordic user group

Minnesanteckningar från EDS Nordic User Group, Stockholm 2013-10-10 Plats: Stockholms universitetsbibliotek När: 2013-10-10 kl. 10-16 Närvarande: Egon Nilsson (Högskolan i Gävle, biblioteket), Mikael Arvidsson (Karlstad universitetsbibliotek), Mikael Blad (Karolinska universitetssjukhuset/Stockholms läns landsting), Jonas Barck (Linnéuniversitets bibliotek), Emma Nolin (Lunds universitetsbibliotek

https://www.ub.lu.se/sites/ub.lu.se/files/minnesanteckningar_fran_eds_nordic_user_group.pdf - 2026-06-01

Minimal structural perturbation of Histatin 5 in crowded environments : Insights from small-angle X-ray scattering, dynamic light scattering, and computer simulations

The structure and dynamics of intrinsically disordered proteins (IDPs) are malleable to solution conditions. Considerable effort has been devoted to understanding the effects of molecular crowding on these properties. Polymer-based crowders, such as polyethylene glycol (PEG) and Ficoll®, are commonly used to simulate the intracellular environment by replicating the high concentration of macromolec

Risk and prognosis of colorectal cancer following bacteraemia with Streptococcus bovis-Streptococcus equinus complex : A Swedish nationwide retrospective cohort study

There is a positive association between bacteraemia with Streptococcus bovis-Streptococcus equinus complex (SBSEC) and colorectal cancer (CRC). However, the relationship between the timing of SBSEC bacteraemia and CRC is not well-established. Associations with other gastrointestinal cancers have also been suggested. Using national registries, we retrospectively examined the incidence of CRC and ot

Different ways of diagnosing selective glomerular hypofiltration syndromes such as shrunken pore syndrome and the associated increase in mortality

BackgroundIn 2015, a selective decrease in the glomerular filtration of middle-sized molecules such as cystatin C compared to small molecules such as creatinine was first described and tentatively termed “Shrunken pore syndrome.” Numerous studies have thereafter found an association between this syndrome (defined by a low eGFRcystatin C to eGFRcreatinine ratio) and mortality and morbidity. In 2023

Biomass cookstove emissions—a systematic review on aerosol and particle properties of relevance for health, climate, and the environment

Around one-fourth of the global population lacks access to clean fuels and technologies for cooking, most of them living in low- and middle-income countries. Reliance on rudimentary and inefficient biomass cookstoves results in high pollutant concentrations that adversely affect the health of those exposed to indoor air pollution, the environment, and the climate. In this study, we systematically

Advancing tire and road wear particles (TRWP) measurements : balancing laboratory conditions and real-world relevance

Non-exhaust emissions from the wear of brakes, tyres, and roads have become an increasing concern in recent years, already surpassing exhaust emissions by mass in many countries. However, there is a lack of studies in the scientific literature on test methods that include both real tyre and road materials. This is crucial for accurately replicating the tribological mechanisms and resulting emissio

Zinc speciation in fine and coarse fly ash particles collected in-flight at a waste incinerator

afe and optimized utilization of waste-to-energy (WtE) fly ash (FA) requires a detailed understanding of the physicochemical properties of its metal constituents. This study provides a comprehensive analysis of the chemical form of Zn in fine (<1 μm) and coarse (>1 μm) FA particles, hypothesized to originate from different formation mechanisms. Size-selective aerosol sampling was performed during

The representation of climate impacts in the FRIDAv2.1 Integrated Assessment Model

Feedbacks from the climate to other components of the coupled human-Earth system are expected to strongly influence the co-evolution of human society and its environment. Representing these feedback loops between climate and society, via the Earth system's response to human activities and the subsequent effect back onto social systems, is essential in order to fully explore the dynamics of the cou

Establishing a Southern Swedish Malignant Melanoma OMICS and Biobank Clinical Capability

Background: The Southern Swedish Malignant Melanoma (SSMM) research team is a truly cross functional group with members from oncology, clinical, surgery, bioinformatics, proteomics, and genomics initiatives. The SSMM’s objectives and goals are to develop, build and utilize cutting edge biobanks and OMICS platforms to better understand disease pathology and drug mechanisms. Within the research team

miR-205 negatively regulates the androgen receptor and is associated with adverse outcome of prostate cancer patients.

Background:The microRNA-205 (miR-205) has been shown to be deregulated in prostate cancer (PCa). Here we continue to investigate the prognostic and therapeutic potential of this microRNA.Methods:The expression of miR-205 is measured by qRT-PCR and in situ hybridisation in a well-documented PCa cohort. An AGO2-based RIP-Chip assay is used to identify targets that are verified with western blots, lu

Galectin-1-binding glycoforms of haptoglobin with altered intracellular trafficking, and increase in metastatic breast cancer patients.

Sera from 25 metastatic breast cancer patients and 25 healthy controls were subjected to affinity chromatography using immobilized galectin-1. Serum from the healthy subjects contained on average 1.2 mg per ml (range 0.7-2.2) galectin-1 binding glycoproteins, whereas serum from the breast cancer patients contained on average 2.2 mg/ml (range 0.8-3.9), with a higher average for large primary tumour

CSR och Företagsprestation – En Undersökning på Stockholmsbörsen

Titel: CSR och Företagsprestation – En Undersökning på Stockholmsbörsen Seminariedatum: 2010-01-08 Ämne: FEKK01, Examensarbete, Kandidatnivå, Finansiering, 15 poäng Författare: Kristoffer Hessedahl & Anders Molin Handledare: Måns Kjellsson Nyckelord: CSR, Stockholmsbörsen, företagsprestation, Tobins Q, Multipel regression Syfte: Undersöka om det finns ett samband mellan CSR och företagens pres

Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond-Blackfan anaemia.

Diamond-Blackfan anaemia (DBA) is a rare congenital disease causing severe anaemia and progressive bone marrow failure. The majority of patients carry mutations in ribosomal proteins, which leads to depletion of erythroid progenitors in the bone marrow. As many as 40% of all DBA patients receive glucocorticoids to alleviate their anaemia. However, despite their use in DBA treatment for more than h

Fler medfödda hjärtfel upptäcks med utökad screening i tre steg

SUMMARYHigh prenatal detection rates of complex congenital heart defects (CHD) Aim: To analyze prenatal detection rates of complex CHD after the implementation of an expanded three-tiered screening model at the Skane University Hospitals in Lund and Malmö in 2015. Methods: Retrospective review of pregnancies screened from January 1, 2015 and being born by June 30, 2018. Complex CHD was defined as