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Insulin-like growth factor-I (IGF-I) regulates cell proliferation and apoptosis, and is thought to play a role in tumour development. Previous prospective studies have shown that higher circulating concentrations of IGF-I are associated with a higher risk of cancers at specific sites, including breast and prostate. No prospective study has examined the association between circulating IGF-I concent

Stratification of women according to their risk of breast cancer based on polygenic risk scores (PRSs) could improve screening and prevention strategies. Our aim was to develop PRSs, optimized for prediction of estrogen receptor (ER)-specific disease, from the largest available genome-wide association dataset and to empirically validate the PRSs in prospective studies. The development dataset comp

Background: A sizeable body of evidence suggests that statins can cease breast cancer progression and prevent breast cancer recurrence. The latest studies have, however, not been supportive of such clinically beneficial effects. These discrepancies may be explained by insufficient power. This considerably sized study investigates the association between both pre- and post-diagnostic statin use and

The combination of a negative D-dimer and a Wells score can rule out, but not confirm, a diagnosis of deep venous thrombosis (DVT). We aimed to identify new diagnostic biomarkers for DVT and to investigate their relationship with hypercoagulability markers [D-dimer and activated protein C-protein C inhibitor (APC-PCI) complex]. We screened 92 cardiovascular-specific proteins in plasma samples from

B-lymphocyte differentiation is one of the best understood developmental pathways in the hematopoietic system. Our understanding of the developmental trajectories linking the multipotent hematopoietic stem cell to the mature functional B-lymphocyte is extensive as a result of efforts to identify and prospectively isolate progenitors at defined maturation stages. The identification of defined proge

AIMS: Cardiovascular disease (CVD) is one of the leading causes of mortality and morbidity worldwide, including in Sweden. The main aim of this study was to explore the temporal trends and spatial patterns of CVD in Sweden using spatial autocorrelation analyses.METHODS: The CVD admission rates between 2000 and 2010 throughout Sweden were entered as the input disease data for the analytic processes

Background: Natural killer (NK) cells and NK T cells (NKT) are vital parts of tumour immunosurveillance. However, their impact on prognosis and chemotherapy response in periampullary adenocarcinoma, including pancreatic cancer, has not yet been described. Methods: Immune cell-specific expression of CD56, CD3, CD68 and CD1a was analysed by immunohistochemistry on tissue microarrays with tumours fro

For excluding deep-vein thrombosis (DVT), a negative D-dimer and low clinical probability are used to rule out DVT. Circulating microR-NAs (miRNAs) are stably present in the plasma, serum and other body fluids. Their diagnostic function has been investigated in many diseases but not in DVT. The aims of present study were to assess the diagnostic ability of plasma miRNAs in DVT and to examine their

Background: Previous studies regarding the association between serum 25-hydroxyvitamin D (25OHD3) and breast cancer risk have not been conclusive. The aim of this study was to investigate the potential association between pre-diagnostic serum 25OHD3 levels and the risk of different subtypes of breast cancer. Materials and methods: The study was based on The Malmö Diet and Cancer Study recruiting 1

Lunds kommuns klimatpolitiska råd bildades hösten 2018 med uppdrag att utvärdera hur Lunds kommuns samlade politik är förenlig med de klimatmål somantagits av kommunfullmäktige. Rådet, som består av forskare från Lunds universitet (LU) och SLU Alnarp, har sammantaget en bred tvär- och mångvetenskaplig kompetens och en gedigen erfarenhet av samverkan med samhället. Samarbetet mellan Lunds kommun oc

A major problem in CTG analysis is that detectionof a suspicious pattern in short intervals so that one can reducethe damage caused by a delay of an automatic monitoringsystem. In this paper, we aim for improving intrapartumsurveillance based on signal processing and machine learningtechniques. We evaluate a classification method on a real dataset.

The histone methyltransferase EZH2 is required for B and T cell development; however, the molecular mechanisms underlying this requirement remain elusive. In a murine model of lymphoid-specific EZH2 deficiency we found that EZH2 was required for proper development of adaptive, but not innate, lymphoid cells. In adaptive lymphoid cells EZH2 prevented the premature expression of Cdkn2a and the conse

Recently, decreased levels of apolipoprotein M (ApoM) were shown to be associated with higher risk of recurrent venous thromboembolism (VTE) in male patients. However, the role of ApoM in primary VTE is unknown. We aimed in our study to analyze the plasma levels of ApoM in patients with VTE in order to evaluate the diagnostic importance of ApoM in primary VTE. A total of 357 patients with suspecte

Melanoma patients treated with oncogenic BRAF inhibitors can develop cutaneous squamous cell carcinoma (cSCC) within weeks of treatment, driven by paradoxical RAS/RAF/MAPK pathway activation. Here we identify frequent TGFBR1 and TGFBR2 mutations in human vemurafenib-induced skin lesions and in sporadic cSCC. Functional analysis reveals these mutations ablate canonical TGFβ Smad signalling, which i

Endometrial cancer risk prediction models including lifestyle, anthropometric and reproductive factors have limited discrimination. Adding biomarker data to these models may improve predictive capacity; to our knowledge, this has not been investigated for endometrial cancer. Using a nested case–control study within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort, we

Voice problems are common among workers in occupations with high demands on oral communication. For sustaining vocal health, it is important to find efficient ways for how to reduce strain on the voice at work, and one way to do so is optimizing the room acoustics for communication. However, to date we do not know enough about what kind of room acoustic conditions that support voice and speech mos

Microsoft Word - Allm studieplan biomed 2015.doc                 Postadress Box 117, 221 00 LUND Telefon växel 046-222 00 00 Telefax 046-222 41 70 E-post info@med.lu.se Internet http://www.med.lu.se Medicinska fakultetsstyrelsen Allmän studieplan för utbildning på forskarnivå i biomedicin http://www.med.lu.se/utbildning/forskarutbildning       (Fastställd  av  Medicinska  fakultetsstyrelsen  2007-

https://www.intramed.lu.se/sites/intramed.lu.se/files/2022-12/allman-studieplan-biomedicin-2015-01-01.pdf - 2026-05-27

WETLAND USE IN THE LUKANGA SWAMPS: IMPLICATIONS FOR ECOSYSTEM INTEGRITY AND INTEGRATED MANAGEMENT OF THE LUKANGA SWAMPS STAKEHOLDER INTERACTIONS IN WETLANDS: IMPLICATIONS FOR SOCIAL ECOLOGICAL SYSTEM SUSTAINABILITY A CASE OF LUKANGA SWAMPS, ZAMBIA Bags of charcoal along the Ndola- Kapiri Road: Picture courtesy of Bwalya 2007 Master of Science Thesis By RHODA NTHENA KACHALI LUND UNIVERSITY MASTERS

https://www.lumes.lu.se/sites/lumes.lu.se/files/rhoda_kachali.pdf - 2026-05-27

Kursbudget Välj kurs HT21 ERROR:#N/A tc={12BF3CFE-92F6-4F3E-A11B-915CDFB72DA4}: [Trådad kommentar] I din version av Excel kan du läsa den här trådade kommentaren, men eventuella ändringar i den tas bort om filen öppnas i en senare version av Excel. Läs mer: https://go.microsoft.com/fwlink/?linkid=870924 Kommentar: Översiktlig koll påå om tilldelning och antal studenter är med. Kursansvarig: Datum:

https://www.biologyeducation.lu.se/sites/biologyeducation.lu.se/files/2021-12/kursbudgetmall_sv.xlsx - 2026-05-27