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Brain glutamine synthetase (GS) is an integral part of the glutamate-glutamine cycle and occurs in the glial compartment. In vivo Magnetic Resonance Spectroscopy (MRS) allows noninvasive measurements of the concentrations and synthesis rates of metabolites. (15)N MRS is an alternative approach to (13)C MRS. Incorporation of labeled (15)N from ammonia in cerebral glutamine allows to measure several
BACKGROUND: There is a lack of understanding of the processes that regulate differentiation in the prostate. OBJECTIVE: To determine localisation, activity, and regulation of cytodifferentiation-modulatory proteins in the human adult prostate. DESIGN, SETTINGS, AND PARTICIPANTS: Eighteen volunteering patients with organ-confined prostate cancer were prospectively enrolled at a single university ho
Objective To determine if familial diabetes burden across multiple kinship levels is associated with hospital-diagnosed COVID-19 in a population-based cohort. Methods We analyzed data from 15,516 participants in the Malmö Diet and Cancer Study (MDCS), a prospective, population-based cohort in southern Sweden. Familial burdens among first-degree relatives (parents, siblings, children) of diabetes,
The current, seemingly uninhibited, growth of AI technologies presents one of the most critical modern day quandaries. The magnitude of its potential to develop, necessitates a deeper look into the legal implications associated which this technology. This thesis aims to describe and analyse the obligations of complete data sets in Article 10 AIA and its relationship with article 5(c) GDPR, using t
Over the past three years, Malmö has witnessed 26 homicides by firearm. Only after that the police responded with vigorous countermeasures like a more effective surveillance, marking high offending and leading criminals, collaboration with other authorities and a massive investment in the defector's program. Ardavan Khoshnood, Criminologist, writes that these measurements have contributed to a sig
Background: Risks that are potentially associated with long-term therapies should be assessed. Objective: The present analyses were performed to determine the risk of malignancy in patients with multiple sclerosis (MS) receiving subcutaneous (sc) interferon (IFN) beta-1a, using pooled safety data from key clinical trials and data from the Merck Serono Global Drug Safety database. Methods: The stan
Purpose The aim of this study was to find clinically relevant MIBG-avid metastatic patterns in patients with newly diagnosed stage 4 neuroblastoma. Methods Diagnostic I-123-MIBG scans from 249 patients (123 from a European and 126 from the COG cohort) were assessed for metastatic spread in 14 body segments and the form of the lesions: "focal" (clear margins distinguishable from adjacent background
Many preterm infants are not capable of exclusive breastfeeding from birth. To guide mothers in breastfeeding, it is important to know when preterm infants can initiate breastfeeding and progress. The aim was to analyse postmenstrual age (PMA) at breastfeeding milestones in different preterm gestational age (GA) groups, to describe rates of breastfeeding duration at pre-defined times, as well as a
Acquired chromosome abnormalities in tumours often reflect pathogenetic events at the gene level. Multicolour fluorescence in situ hybridisation (FISH) with single-copy probes offers extensive possibilities to characterise chromosome breakpoints in relation to the physical map of the human genome. This approach is based on the construction of comprehensive EST- based maps, combinatorial labelling
Objective. Lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH) are a common condition in men, and their incidence increases with age. The objective of this study was to evaluate the potential cost-utility of microwave thermotherapy, specifically the ProstaLund Feedback Treatment (PLFT), versus alpha-blockade in Swedish patients with LUTS due to BPH. Material and methods.
The taxation of the digital economy has become a relevant subject, as business models and value creation chains of all sectors have been transformed bringing challenges to the international tax system and parameters for the allocation of taxing rights between source and residence jurisdictions. In view of these changes, the European Commission has published two proposals for directives on the taxa
Background: Care decisions for older patients in acute situations are challenging to make, and there is limited knowledge of support in home healthcare settings, where older patients receive ongoing health care from, for example, community health nurses. Therefore, this study aimed to describe the support for all involved in acute situations when a community health nurse was called, as experienced
Background: Voluntary self-exclusion from gambling is a common but underdeveloped harm reduction tool in the management of gambling problems or gambling disorders. Large-scale, multi-operator, and operator-independent self-exclusion services are needed. A recent nationwide multi-operator self-exclusion service in Sweden (Spelpaus), involving both land- and web-based gambling sites, is promising, b
Finnish oral communication is often considered to be something of a minimalist exercise. A well-known expression of such communication is the so-called Proletariat Trilogy by the Finnish film-maker Aki Kaurismäki. This study presents an analysis of persuasive and argumentative dialogues in the manuscript to Shadows in Paradise. The approach is based on Searle’s speech acts, Grice’s conversational
Atrial fibrillation and heart failure have both been suggested to increase stroke and dementia risk. However, in observational studies, reversed causation and unmeasured confounding may occur. To mitigate these issues, this study aims to investigate if higher genetic risk for atrial fibrillation and heart failure increases dementia and stroke risk. Data were obtained from the population-based Goth
lum_2007_04 LUM Lunds universitets magasin | Nr 4 | 2007 Tropik botanik Avhopp efter Medfaks storbyggen Metallbrist hotar stålet LUM nr 4 | 2007 ägget är löst LUM nr 4 | 2007 Första äggen fick han som nykläckt gynekolog. Fyrtiofem år och flera hundra ägg senare skänker Nils-Otto Sjöberg sin magnifika äggsamling till Medicinska fakulteten. Äggen kommer att finnas till allmän beskå- dan på kvinno
https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-4-2007.pdf - 2026-07-07
