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The association between vitamin D status and hepatocellular carcinoma (HCC) has not been well investigated, despite experimental evidence supporting an important role of vitamin D in liver pathophysiology. Our objective was to investigate the association between prediagnostic circulating 25-hydroxyvitamin D [25(OH)D] serum levels and the risk of HCC in a prospective, nested case-control study amon
Assessment of the long-term safety and efficacy of liquid inhaled insulin via AERx((R)) insulin Diabetes Management System (iDMS) in a basal/bolus treatment regimen of adults with Type 1 diabetes. Patients were randomized 2 : 1 to prandial inhaled (n = 205) or subcutaneous (s.c.) (n = 99) insulin, plus one/two daily injections of neutral protamine Hagedorn (NPH) insulin for 12 months. The primary
BACKGROUND: /st>The relative respiratory effects of fentanyl and remifentanil, administered as i.v. bolus, have not previously been studied. We determined what remifentanil bolus dose gave the same maximum depression of ventilation as 1 µg kg(-1) of fentanyl. METHODS: /st>Twelve healthy volunteers rebreathed in a system designed to dampen variations in end-tidal carbon dioxide tension so that me
Aims: The Swedish National Inpatient Registry is an important source of data for numerous epidemiological studies, amongst them studies on chronic obstructive pulmonary disease (COPD). General validation studies indicate that in general 85-95% of diagnoses reported are correct, but this is not true for all groups of diseases, why specific validation studies are of great importance. Methods: Charts
Aluminium och Aluminiumlegeringar, som förutom aluminium innehåller några få procent av andra metaller, används i flera olika produkter såsom mobiltelefoner, flygplan, bilar och byggnader. Bland annat är aluminiumlegeringar det mest använda byggtekniska materialet efter järnlegeringar. Det breda användandet av aluminiumlegeringar förklaras av de många fördelaktiga egenskaperna. Till exempel har leIn this thesis, the studies of native and anodic oxides on both aluminum model single crystal surfaces as well as on aluminum alloys found in applications are presented. The focus has been on the characterization in situ as the oxide is growing by an electrochemical process called anodization. For the investigations, a combination of various X-ray scattering and spectroscopy methods, as well as el
Syftet med denna uppsats är att precisera hävningsgrunderna och hävningens rättsverkningar enligt standardavtalen AB 04 och ABT 06. För att kunna besvara de ställda frågorna utgår arbetet från sådan rättsdogmatisk teori och metod som kan sägas utgöra traditionell rättsvetenskap. För kommersiella entreprenadavtal saknas direkt tillämpliga obligationsrättsliga lagregler. Detta innebär att de förhandThe purpose of this study is to clarify the grounds for termination, and the legal consequences of termination, according to the standard agreement system constituted by AB 04 and ABT 06. The study is based on such theory and method which represents traditional jurisprudence. In Sweden commercial construction contracts are not subject to any specific legislative regulation. For lack of formally ap
Building in a manner that minimizes environmental impact has become a major part of the construction industry. Despite increased knowledge in this area the development is moving slowly. The purpose of this thesis is to give the reader an idea of the approach to green construction of civil engineering. The definition of a green tender is defined by the people who have been interviewed. The question
OBJECTIVES: To assess the coexistence of hypertension and diabetes, associations with cardiovascular risk factors and the achievement of current treatment goals. DESIGN: A community-based, cross-sectional, observational study. SETTING: Hypertension and diabetes outpatient clinics in primary health care, Skara, Sweden. SUBJECTS: All patients (n = 1116; 488 men, 628 women) who performed an annual fo
Background: This project plan proposes a new learning activity and assessment model of medical students' empathy and communication skills. An empathic ability and communication skills are crucial in a student future role as a physician. Empathy and communication skills are also Entrustable Professional Activities in most undergraduate medical educational programs1.Method: The students are first in
To meet climate targets, expanding Populus spp. tree cultivation is proposed as a potential biomass feedstock, especially on agricultural land that does not come into conflict with food production. However, biomass potential assessments typically overlook landowners' perspectives, risking a gap between theoretical potentials and realisation. Here, we test empirical consequences of two hypotheses b
There are currently no reliable biomarkers to predict clinical response to pharmacological treatments of depressive disorders. Peripheral blood 5-hydroxytryptamine (5-HT; serotonin) has been suggested as a biomarker of antidepressant treatment response, but there has not been an attempt to systematically summarize and evaluate the scientific evidence of this hypothesis. In this systematic review w
Background: Depressed suicide attempters are, according to some earlier studies, treated more often with antipsychotics than depressive non-suicide attempters. Cluster B personality disorders, especially borderline personality disorder, are associated with a high suicide risk, and antipsychotics are commonly used for the reduction of symptoms. However, no previous study has taken comorbid personal
Traumatic brain injury (TBI) increases the risk of delayed neurodegenerative processes, including Parkinson’s disease (PD). Interleukin-1beta (IL-1β), a key pro-inflammatory cytokine, may promote secondary injury development after TBI. Conversely, neutralizing IL-1β was found to improve functional recovery following experimental TBI. However, the mechanisms underlying the behavioral improvements o
Introduction eHealth, defined by WHO as: “the transfer of health resources and healthcare by electronic means” are expected to increase communication between healthcare providers and patients and increase accessibility and patient participation in healthcare. The aim of this research programme is to: 1) develop a sustainable multidisciplinary environment for advancing, evaluating, and implementin
The response of soil microbial activity to climate warming has been predicted to have a large destabilising effect on the carbon cycle. However, the nature of this feedback remains poorly understood, especially in tropical ecosystems and across annual to decadal timescales. We studied the response of bacterial community growth to 2 and 11 years of altered temperature regimes, by translocating soil
Following stroke, attenuation of detrimental inflammatory pathways might be a promising strategy to improve long-term outcome. In particular, cascades driven by pro-inflammatory chemokines interact with neurotransmitter systems such as the GABAergic system. This crosstalk might be of relevance for mechanisms of neuronal plasticity, however, detailed studies are lacking. The purpose of this study w
Background: Emerging data suggest a complex pathophysiology of chronic subdural hematoma (CSDH) to which an inflammatory response might contribute. The complement system is activated in acute traumatic setting, although its role in CSDH is unknown. To investigate the complement system in CSDH pathophysiology, we analyzed blood and hematoma fluid biomarkers, as well as immunohistochemistry of the C
INTRODUCTION: Low birth weight is an important measure of the health of pregnant women and newborns. We investigated the prevalence of low birth weights in India over nearly three decades to assess trends and convergence across states.METHODS: Data came from five waves of the National Family Health Survey (1992-93 to 2019-21). The prevalence of low birth weight was estimated. To explore the sensit
All Application Reference Number Application Country Code ORGANISATION- Institution Name Name of the organisation in English Organisation City Organisation Country Name Institutional code PIC 103242-LA-1-2014-1-AT-E4AKA1-ECHE AT KATHOLISCH-THEOLOGISCHE PRIVATUNIVERSITÄT LINZ CATHOLIC THEOLOGICAL PRIVATE UNIVERSITY LINZ LINZ Österreich A LINZ11 215141-LA-1-2014-1-AT-E4AKA1-ECHE AT JOSEPH HAYDN KONS
https://www.lu.se/sites/www.lu.se/files/eche_2014_awardedapplications.xlsx - 2026-07-13
