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Walking is a primary mode of transport in urban Africa, yet it remains unsafe, challenging, and unpleasant. In contrast, several European countries have implemented systematic policies to promote walking through Safe System principles. This study compares pedestrian safety in three African countries (Tanzania, Ghana, Zambia), with three European countries with excellence in road safety and Safe Sy
Background: Magnetic resonance imaging (MRI) has traditionally been preferred over computed tomography (CT) for segmentation of intracranial structures due to its superior low contrast resolution. However, a reliable CT-based segmentation could improve patient management when MRI is not practical. Despite advancements in CT imaging, such as enhanced tissue differentiation using virtual monoenerget
A search for the production of a Higgs boson and one or more charm quarks, in which the Higgs boson decays into a photon pair, is presented. This search uses proton-proton collision data with a centre-of-mass energy of s = 13 TeV and an integrated luminosity of 140 fb−1 recorded by the ATLAS detector at the Large Hadron Collider. The analysis relies on the identification of charm-quark-containing
BACKGROUND: HYPO-RT-PC is a phase 3 trial comparing ultra-hypofractionated and conventionally fractionated radiotherapy in intermediate-to-high-risk localised prostate cancer. This 10-year update reports long-term efficacy and toxicity outcomes.METHODS: In this open-label, randomised, phase 3, non-inferiority trial done in ten centres in Sweden and two in Denmark, we recruited men aged 75 years or
This paper presents a search for physics beyond the Standard Model targeting a heavy resonance visible in the invariant mass of the lepton-jet system. The analysis focuses on final states with a high-energy lepton and jet, and is optimised for the resonant production of leptoquarks — a novel production mode mediated by the lepton content of the proton originating from quantum fluctuations. Four di
This article reports on a search for dijet resonances using 132 fb−1 of pp collision data recorded at (Formula presented) ¼ 13 TeV by the ATLAS detector at the Large Hadron Collider. The search is performed solely on jets reconstructed within the ATLAS trigger to overcome bandwidth limitations imposed on conventional single-jet triggers, which would otherwise reject data from decays of sub-TeV dij
Artificial Intelligence is advancing rapidly, raising critical concerns about the integrity of digital content, particularly in sensitive domains such as medical imaging. Recent AI techniques, such as Generative Adversarial Networks (GANs) and diffusion models, can generate highly realistic synthetic medical images, posing risks of misdiagnosis, inappropriate treatment, and other adverse outcomes.
Climate change is recognized as one of the greatest environmental threats facing the world today. To tackle this problem, a protocol was adopted in Kyoto in 1997 which establishes legally binding commitments to developed countries to bring down the emissions of six major greenhouse gases by 5.2% compared to the year 1990. Three flexibility mechanisms have been provided to developed countries to ac
This paper aims to design a highly efficient adsorbent to capture phosphoprotein in a facile way. One of the applications would be removing the allergenic β-casein from vaccines. To avoid the use of organic reagents and improve the capacity of immobilized metal ion affinity chromatography applied for bio-products at neutral pH, synergistic functional Core@Brush microspheres were designed utilizing
Despite laws, policies and visions to create cities and societies for all, barriers still exclude persons with disabilities from using buildings and public places. Our study aimed to identify choices made during the urban development process that include or exclude users in the built environment; how and when these choices arise during the process; and what is needed to implement universal design
Abstract in Portuguese:Referências a paisagens e lugares são elementos centrais nas narrativas tradicionais de falantes da língua Dâw (Naduhup,Amazônia brasileira). Essa ênfase na referência espacial é estabelecida principalmente por meio de orações adverbiaislocativas que são frequentemente repetidas ao longo do discurso. Sua função é relacionar um evento a um lugar, estabelecerreferência à inforReferences to landscape and places are central in traditional narratives by speakers of Dâw (Naduhup, Brazilian Amazon). This emphasis on spatial reference is primarily established through locative adverbial clauses that are often repeated throughout the discourse. Their function is to relate an event to a place, establish reference to locative information mentioned earlier in discourse, and provi
Water is an urgent topic of research in cultural and feminist geographies. Geographers study water through interdisciplinary approaches including critical resource geography, political ecology, and feminist theory. An emerging area of research within cultural and feminist geography considers the affective, emotional qualities of water as part of water’s social and political ramifications. Methodol
Background: Adipic acid (AA) is one of the most important industrial chemicals used mainly for the production of Nylon 6,6 but also for making polyurethanes, plasticizers, and unsaturated polyester resins, and more recently as a component in the biodegradable polyester poly(butylene adipate terephthalate) (PBAT). The main route for AA production utilizes benzene as feedstock and generates copious
PURPOSE: To analyze the outcomes of cataract surgery complicated by posterior capsule rupture (PCR). SETTING: European clinics affiliated to the European Registry of Quality Outcomes for Cataract and Refractive Surgery (EUREQUO). DESIGN: Retrospective cross-sectional register-based study. METHODS: Data were retrieved from the EUREQUO between January 1, 2008, and December 31, 2018. The database con
Aim: This study investigated the changes in health-related quality of life from diagnosis to 1 year after diagnosis in breast cancer (BC) patients and the influence of clinical, psychological, and sociodemographic variables. An additional aim was to explore the mediating and moderating effects of resilience on changes in health-related quality of life. Methods: A longitudinal population-based stud
Background Biomarkers based on detecting prostate cancer (PCa)-specific transcripts in blood are associated with inferior outcomes, but their validation in a clinical context is lacking. Objective To determine whether detecting enhanced transcripts for PCa in whole blood using an analytically valid assay has prognostic significance relative to circulating tumor cell (CTC) enumeration. Design, sett
In the transition to more sustainable travel behaviour, there is a need to reduce car mileage for all sorts of trips including everyday leisure trips for social and recreational purposes. In this case study, qualitative interviews were conducted to improve and deepen the understanding of transport mode choice for such trips. The analyses of factors affecting mode choice for everyday leisure purpos
Background. Prostate specific antigen (PSA) is a zymogen of a 33‐kilodalton (kD) serine proteinase with extensive similarity to glandular kallikreins. The mechanism responsible for converting the zymogen into active proteinase has not been defined, but active PSA may be irreversibly inactivated in vitro by two of the major proteinase inhibitors in blood: alpha1‐antichymotrypsin and alpha2‐macroglo
In this (Danish) article, Tabita Rosendal provides an overview of China's use of Buddhist diplomacy in Sri Lanka, arguing that the CCP is utilizing Buddhist strategic narratives in order to pave the way for the Belt and Road Initiative's (BRI) smooth implementation. She summarizes the BRI's progress in Sri Lanka, China's use of Buddhist diplomacy, as well as China's Buddhist strategic narratives,
Background and purpose — Older patients with a displaced femoral neck fracture (FNF) are often treated with a cemented primary hemiarthroplasty (HA). The DAICY trial investigates whether high-dose dual-impregnated antibiotic-loaded cement (DIAC) including gentamicin and clindamycin can reduce the risk of periprosthetic joint infection (PJI) in comparison with low-dose single-impregnated gentamicin
