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Background and Objectives Structural brain MRI and blood-based phosphorylated tau (p-tau) measures are among the least invasive and least expensive Alzheimer's disease (AD) biomarkers to date. The extent to which these biomarkersmay outperformone another in predicting future Alzheimer dementia diagnosis is poorly understood, however. This study investigated 2 specific AD biomarkers, i.e., a cortic
Both phosphoryl and sulfuryl transfers are ubiquitous in biology, being involved in a wide range of processes, ranging from cell division to apoptosis. Additionally, it is becoming increasingly clear that enzymes that can catalyze phosphoryl transfer can often cross-catalyze sulfuryl transfer (and vice versa). However, while there have been extensive experimental and theoretical studies performed
Women have made substantial gains in education in recent decades and outperformmen in educational attainment across the OECD, but the consequences of this reversal of the gender gap in education (RGE) have not been well researched. In this study, we address the association between the RGE and partnering, employment, and support for a right-wing populist party in Sweden. Of note, we explore the dif
Women have made substantial gains in education and outperform men regarding educational attainment across the OECD, but the consequences of this reversal of the gender gap in education (RGE) have not been well researched. We address the association between the RGE and partnering, employment, and support for a right-wing populist party in Sweden. We explore the differential impacts of women's educa
This thesis investigates the role of advanced atmospheric inversion techniques and ∆¹⁴CO₂ observations in improving the accuracy of regional CO₂ flux estimates across Europe. Accurate quantification of fossil fuel emissions and biospheric fluxes is essential for understanding regional carbon budgets and supporting climate policy. However, significant uncertainties persist due to limited observatio
IMPORTANCE During the past decade, spinal surgical procedures have been increasingly performed on an ambulatory basis, a change in clinical practice supported only by observational evidence thus far. There have been no randomized clinical trials (RCTs) comparing ambulatory care with inpatient care after any spinal surgery. OBJECTIVE To assess whether ambulatory care is noninferior to overnight hos
Following the upgrade of the LNLS injector system with the addition of a 500 MeV booster synchrotron, the storage ring in vacuum ferrite injection kicker magnets started to show overheating due the interaction with high frequency electromagnetic fields induced by the electron beam in large currents. In this paper, we describe the design of a new ceramic chamber for the kickers, which minimize this
Children's outdoor play and access to nature are important for their health and development of environmental agency but there is a global decline of green spaces available to them. The aim is to explore the possibilities of creating nature-based outdoor settings for play and learning which benefit children as well as the wildlife and wider ecosystems. A fieldwork on developing nature based play se
Echinolittorina malaccana, a marine gastropod living on rocky shores along the Indo-West Pacific coasts, shows consistent mate choice in which males prefer to mate with females slightly larger than themselves. Previous studies suggest that the strength of this preference is, to a certain extent, context dependent, being influenced by both demographic and individual (potentially genetic) factors. T
While the Convention on the Rights of the Child (UNCRC) does not address research, it instigated a recognition that decisions concerning children and youth must be based on knowledge of their experiences from their own perspective and consider their specific views and wishes, highlighting their right to be heard. Participatory research underscores this right, arguing the engagement of children and
Objective: Despite the increasing number of fenestrated and branched endovascular aortic repair (F/B-EVAR) procedures, evidence on post-operative antiplatelet therapy is very limited. This study aimed to investigate the role of single antiplatelet therapy (SAPT) vs. double antiplatelet therapy (DAPT) after F/B-EVAR in 30 day and follow up outcomes. Methods: A multicentre retrospective analysis was
Land cover governs the biogeophysical and biogeochemical feedbacks between the land surface and atmosphere. Holocene vegetation-atmosphere interactions are of particular interest, both to understand the climate effects of intensifying human land use and as a possible explanation for the Holocene temperature conundrum, a widely studied mismatch between simulated and reconstructed temperatures. Prog
The rheological properties of bituminous binders tested with a dynamic shear rheometer (DSR) as a function of loading time and temperature can more accurately represent real road situations with rising traffic loads and densities combined with climatic change. This method is more effective than traditional methods such as measuring the softening point and penetration. Complex shear modulus and pha
Energy management in urban areas is challenging due to diverse energy users, dynamics environmental conditions, and the added complexity and instability of extreme weather events. We incorporate adaptive reinforcement learning (ARL) into energy management (EM) and introduce a novel approach, called ARLEM. An online, value-based, model-free ARL engine is designed that updates its policy periodicall
To increase women’s interest in STEM (Science, Technology, Engineering and Mathematics), interventions that target self-efficacy and belongingness are needed. For this purpose, this study designed and tested two interventions. In Study 1, we tested if a video with female role models increases young women’s expected belongingness and interest in engineering. In Study 2, we tested if positive feedba
While there is ample evidence supporting genetic control of migratory behaviour in short-lived passerines, long-lived social species have been assumed to rely solely on cultural inheritance of migratory routes. Evidence from experimental studies supporting this idea is scarce. We tested whether the moult migration in taiga bean geese Anser fabalis has an inherited component or whether the birds ne
In the work of writing this report, four leading municipal research environments - CERUM, CKS, KEFU, and KFi - with the support of Kommuninvest, have collaborated to explore and understand the complex challenges that Swedish municipalities have had to manage during the transition from relatively favorable economic times to more challenging times, including changed economic conditions and a deterio
