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Grunderna i cancerbehandling är kirurgi, strålterapi och behandling med cancerläkemedel, ofta i kombination med varandra. Regimer med cancerläkemedel som definierar det eller de läkemedel som används, deras doser, hur ofta och hur länge de ska ges, har utvecklats och används för olika cancerdiagnoser. Flera professioner inom sjukvården är involverade i behandlingen: läkaren som ordinerar läkemedleThe basics in cancer treatment are surgery, radiation therapy, and treatment with cancer drugs, often combined. Chemotherapy regimens that define the drugs used, the dosage, the frequency and duration of drug administration, have been developed and used for different cancer diagnoses. Several healthcare professionals are involved in the treatment: the physician prescribing the drugs, the pharmacis

Pseudomyxoma Peritonei (PMP) is a rare peritoneal malignancy, most commonly originating from a perforated epithelial tumour of the appendix. Given its rarity, randomized controlled trials on treatment strategies are lacking, nor likely to be performed in the foreseeable future. However, many questions regarding the management of appendiceal tumours, especially when accompanied by PMP, remain unans

We report on measurements of a charge-dependent flow using a novel three-particle correlator with ALICE in Pb-Pb collisions at the CERN Large Hadron Collider (LHC), and discuss the implications for observation of local parity violation and the chiral magnetic wave (CMW) in heavy-ion collisions. Charge-dependent flow is reported for different collision centralities as a function of the event charge

The core-multishell wurtzite structure (In,Ga)As–(Ga,Al)As–(Ga,Mn)As semiconductor nanowires have been successfully grown on GaAs(111)B substrates using MBE technique. The nanowires cores were grown with gold eutectic catalyser in vapour–liquid–solid growth mode. The double shell overgrowth, on the side facets of nanowires, was performed using lower substrate temperature (about 400 ◦C, and 230 ◦C,

Objective: To investigate the risk of procedure-related major amputation attributable to revascularization for intermittent claudication (IC) in a population-based observational cohort study. Methods: All patients who underwent open or endovascular lower limb revascularisation for IC in Sweden between 12 May 2008 and 31 December 2012 were identified from the Swedish National Quality Registry for V

BACKGROUND AND OBJECTIVES: The aims of this multi-institutional study were to assess the feasibility of iterative cytoreductive surgery (iCRS)/hyperthermic intraperitoneal chemotherapy, iCRS in colorectal peritoneal carcinomatosis (CRPC), evaluate survival, recurrence, morbidity and mortality outcomes, and identify prognostic factors for overall survival.METHODS: Patients with CRPC that underwent

A search for magnetic monopoles and high-electric-charge objects is presented using 34.4 fb-1 of 13 TeV pp collision data collected by the ATLAS detector at the LHC during 2015 and 2016. The considered signature is based upon high ionization in the transition radiation tracker of the inner detector associated with a pencil-shape energy deposit in the electromagnetic calorimeter. The data were coll

Water demand growth coupled with its high spatial-temporal mismatch of water resources will lead to an increasing water scarcity worldwide. In order to investigate a robust long-term water stress for ecosystems and regions across China, the improved maximum entropy production (MEP) method was utilized to obtain a reliable evapotranspiration (ET) product during 1982–2015. Afterwards four water stre

This thesis is a study of Twelver Shi’a Islam in the context of Azeri-Turkish Muslims living in the Anatolia-Caucasus borderlands of Northeastern Turkey. Taking the sonic as the central focus and field of enquiry I listen to the ways that sound mediates between bodies, both somatic and social, and the divine in the ritual and quotidian lives of Shi’i practitioners. I argue that sound, voice and li

Electrification of commercial heavy vehicles has led to the offer of different electric drive-based powertrain architectures, most of them with the adaptation of the diesel engine based architecture. Due to the limited driving range possible, optimal configuration of the powertrain becomes a vital task with the battery as the energy source, which also takes a significant portion of payload capacit

In the challenge to reduce CO2, NOx and PM emissions, the application of natural gas or biogas in engines is a viable approach. In heavy duty and marine, either a conventional dual fuel (CDF), or a reactivity-controlled compression ignition (RCCI) approach is feasible on existing diesel engines. In both technologies a pilot diesel injection is used to ignite the premixed natural gas. However, the

BackgroundLiver metastases are a common consequence of colorectal cancer. When feasible, surgical resection is first-line treatment. Synchronous disease can be treated with different strategies. Traditionally, the primary tumour is resected first followed by resection of the liver metastases (bowel-first). The other option, which is increasing, is the liver-first strategy, where resection of the l

PMCA4 is a critical regulator of Ca2+ homeostasis in mammalian cells. While its biological and prognostic relevance in several cancer types has already been demonstrated, only preclinical investigations suggested a metastasis suppressor function in melanoma. Therefore, we studied the expression pattern of PMCA4 in human skin, nevus, as well as in primary and metastatic melanoma using immunohistoch

Housing expenses have the highest share in household budgets of low-income groups in Copenhagen leading to affordability problems. To provide affordable housing (AH) for low-income groups, the municipality developed a zoning plan in 2015 aimed to reserve up to 25% of land for new AH production. This qualitative case study compares the affordability of homes produced by private sector and nonprofit

The accuracy and precision of frameless neuronavigation as compared to conventional frame-based stereotaxy for implantation of deep brain stimulation (DBS) electrodes were studied in 14 patients with essential tremor. DBS electrodes were implanted bilaterally in the ventrolateral thalamus [ventrointermediate nucleus ( VIM)] in one procedure. Frameless neuronavigation was used on one side and the c