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Chronic kidney disease (CKD) is common in older adults, and its burden is expected to increase in older populations. Even if the knowledge on the approach to older patient with CKD is still evolving, current guidelines for pharmacological management of CKD does not include specific recommendations for older patients. Additionally, decision-making on renal replacement therapy (RRT) for older patien
We consider optimal channel shortener design for reduced-state soft-output Viterbi equalizer (RS-SOVE) in singlecarrier (SC) systems. To use RS-SOVE, three receiver filters need to be designed: a prefilter, a target response and a feedback filter. The collection of these three filters are commonly referred to as the “channel shortener”. Conventionally, the channel shortener is designed to transfor
The borehole thermal resistance is both an important design parameter and a key performance characteristic of a borehole heat exchanger. Another quantity that is particularly important for deep borehole heat exchangers is the internal thermal resistance between the upward-flowing and downward-flowing fluid channels in the borehole. The multipole method is a well-known and robust method to compute
AbstractBackground Mitral regurgitation (MR) has many etiologies; the most common is degenerative disease. If not corrected, severe MR may cause left and right ventricular heart failure. Mitral valve (MV) repair is the gold standard for treatment of MR. All repair techniques include MV annuloplasty, but various techniques are employed to repair the valvular apparatus. The classical technique of le
ESS, the European Spallation Source, will be a major user facility at which researchers from academia and industry will investigate scientific questions using neutron beams. ESS will deliver its protons to a solid, rotating tungsten target, which will in turn generate neutrons. A linear accelerator (Linac) creates protons at the ion source, accelerates them to an appropriate energy and steers them
Almost half of all lower leg amputations are performed in patients with diabetes. In over 70 per cent of these cases, amputation is precipitated by progression of foot ulceration to deep gangrenous infection. Most foot ulcers are preceded by trauma, usually due to ill-fitting shoes, and are precipitated by sensory motor neuropathy with varying degrees of peripheral vascular disease. The Swedish Me
With the RB3-LAND setup at GSI we have measured exclusive relative-energy spectra of the Coulomb dissociation of C18 at a projectile energy around 425A MeV on a lead target, which are needed to determine the radiative neutron-capture cross sections of C17 into the ground state of C18. Those data have been used to constrain theoretical calculations for transitions populating excited states in C18.
The cost of ownership of a power plant is partly governed by the efficiency of the turbine island. The turbine stands for the production revenues when transforming the energy in fuel into electric power and district heating. One gauge of the quality of the individual processes is the component efficiency - the current work addresses the turbine part of the power plant. The turbine efficiency is d
This paper presents a study of the physical limitations for radio frequency absorption in gold nanoparticle (GNP) suspensions. A spherical geometry is considered consisting of a spherical suspension of colloidal GNPs characterized as an arbitrary passive dielectric material which is immersed in an arbitrary lossy medium. A relative heating coefficient and a corresponding optimal near field excitat
Neural transplantation holds promise for focal CNS repair. Owing to the shortage of human donor material, which is derived from aborted embryos, and ethical concerns over its use, animal donor tissue is now considered an appropriate alternative. In the USA, individuals suffering from Parkinson's disease, Huntington's disease, focal epilepsy or stroke have already received neural grafts from pig em
Transplantation of neural tissue is an effective therapeutical approach in Parkinson's disease, but the method is constrained by the lack of suitable donor material. Embryonic neural tissue from pigs, xenografts, is considered as an alternative source of donor tissue. The attitudes towards neural tissue grafting in general and xenografts in particular were investigated by interviewing a group of p
We present the development of a specialized concrete for neutron shielding at neutron research facilities, based on the addition of hydrogen atoms in the form of polyethylene and also B4C for enhancing the neutron capture properties of the concrete. We show information on the mechanical properties of the concrete and the neutronics, in particular its relevance to modern spallation neutron sources,
Honeybees face many parasites and pathogens and consequently rely on a diverse set of individual and group-level defenses to prevent disease. The crop microbiota of Apis mellifera, composed of 13 Lactic Acid Bacterial (LAB) species within the genera Lactobacillus and Bifidobacterium, form a beneficial symbiotic relationship with each other and the honeybee to protect their niche and their host. Po
Combining straightforward molecular imprinting with orthogonal click chemistry and accessible fluorescent dyes, a modular approach has been developed to assemble turn-on optical sensors based on fluorescence resonance energy transfer in molecularly imprinted nanoparticles.
