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Monolithic class-D audio amplifiers typically feature built-in over current protection circuitry that shuts down the amplifier in case of a short circuit on the output speaker terminals. To minimize cost, the threshold at which the device shuts down must be set just above the maximum current that can flow in the loudspeaker during normal operation. The current required is determined by the complex

The gene for the human glandular kallikrein, prostate-specific antigen, has been cloned. The sequence of 7130 nucleotides encompassing the gene and 633 bp of 5' and 639 bp of 3' flanking DNA has been determined. The translation initiation site was slightly heterogeneous, yielding 5' non-translated leader sequences of 41 and 35 bp. The gene is divided into five exons, with introns located at positi

En delrapport från forskningsprojektet "Omstrukturering av sjukvårdsutbudet inom ett sjukvårdsområde"

Participation is about finding consensus in diversity and reflects a normative shift towards multiple-use values that recognise that forest management should blend multiple management objectives into a coherent set of practices. A framework to incorporate interest groups' values and needs into functional forest management systems has yet to be institutionalised in contemporary forest policy and ma

The mechanisms by which gestational infections, blood incompatibility, birth weight, mother's age and other prenatal or neonatal events increase the risk for type 1 diabetes are not understood. Studies so far have been retrospective, and there is a lack of population-based prospective studies. The possibility identifying children at type 1 diabetes risk among first-degree relatives has resulted in

A water activity control system for enzymatic synthesis in organic media, for litre-scale reactors has been constructed. Water activity, a(w), is a key factor when using enzymes in non-conventional media and the optimum value varies for different enzymes. The control system consists of a water activity sensor in the headspace of a jacketed glass reactor (equipped with narrow steel tubes to introdu

Antibody-based microarray is a novel proteomic technology setting a new standard for molecular profiling of non-fractionated complex proteomes. The first generation of antibody microarrays has already demonstrated its potential for generating detailed protein expression profiles, or protein atlases, of human body fluids in health and disease, paving the way for new discoveries within the field of

There is biological evidence that human actions are composed out of action primitives, like words and sentences being composed out of phonemes. Similarly to language processing, one possibility to model and recognize complex actions is to use grammars with action primitives as the alphabet. A major challenge here is that the action primitives need to be recovered first from the noisy input signal

We present a new way of performing hypothesis tests on scattering data, by means of a perturbatively calculable classifier. This classifier exploits the “history tree” of how the measured data point might have evolved out of any simpler (reconstructed) points along classical paths, while explicitly keeping quantum–mechanical interference effects by copiously employing complete leading-order matrix

Programming robots for tasks involving force interaction is difficult, since both the knowledge of the task and the dynamics of the robots are necessary. An immersive haptic interface for task demonstration is proposed, where theoperator can sense and act through the robot. This is achieved by coupling two robotic systems with virtual constraints such that they have the same coordinates in the ope

Xylan has a main chain consisting of β-1,4-linked xylose residues with diverse substituents. Endoxylanases cleave the xylan chain at cleavage sites determined by the substitution pattern and thus give different oligosaccharide product patterns. Most known endoxylanases belong to glycoside hydrolase (GH) families 10 and 11. These enzymes work well on unsubstituted xylan but accept substituents in c

In this note the veil of ignorance approach is tested as a basis for empirically determining the shape of the social welfare function for QALYs. An experiment is carried out where the participants choose between different societies that differ with respect to per capita QALYs and the distribution of QALYs. The answers are analyzed using logistic regression analysis, According to the results the re

Most experimental and numerical investigations of high-pressure homogenizers assume that the valve is fed with a constant flowrate. However, technical homogenizers use piston pumps with either 3 or 5 pistons (production- and pilot-scale machines) or a single piston (laboratory-scale machines). This results in flow pulsation. It is still unknown to what extent this influences valve hydrodynamics. M

Purpose Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis, with a 5-year survival of, 10% because of diffuse symptoms leading to late-stage diagnosis. That survival could increase significantly if localized tumors could be detected early. Therefore, we used multiparametric analysis of blood samples to obtain a novel biomarker signature of early-stage PDAC. The signature was derived from

The max-bisection and min-bisection problems are to find a partition of the vertices of a graph into two equal size subsets that, respectively, maximizes or minimizes the number of edges with endpoints in both subsets. We design the first polynomial time approximation scheme for the max-bisection problem on arbitrary planar graphs solving a long-standing open problem. The method of solution involv

Prostate-specific antigen (PSA) is the most widely used marker of prostate cancer. Assays for PSA are based on anti-PSA antibodies, and the characterization and selection of these antibodies is important for determining their optimum performance. In our study, we characterized the reactivity of 53 antibodies, submitted to the ISOBM TD-3 PSA Workshop, using free PSA, PSA complexed to alpha1-antichy