Filtyp
Current hemophilia B treatment guidelines recommend routine prophylaxis with factor IX (FIX) replacement products, tailored to maintain plasma activity at levels that will prevent bleeds. However, plasma FIX activity may not be the primary determinant or best indicator of hemostatic efficacy due to its extravascular distribution. FIX replacement therapy has evolved to include extended half-life (E
Immunoglobulin G (IgG) glycosylation modulates antibody activity and represents a major source of heterogeneity within antibody preparations. Depending on their glycosylation pattern, individual IgG glycovariants present in recombinant antibody preparations may trigger effects ranging from enhanced pro-inflammatory activity to increased anti-inflammatory activity. In contrast, reduction of IgG gly
The phenomenon of increasing correlation between asset returns in economic downturns will be investigated with two different approaches and tried to be explained by different macroeconomic variables. The first approach, namely the classic method of measuring correlation with time series is contrasted with an extended method of cross-sectional correlation measurement proposed by Solnik (2000). The
In a previous study we presented data indicating that the expanded population of CD4(-)CD8(-) (DN) alphabeta T cells in TCRalpha-chain-transgenic mice was partially if not entirely derived from gammadelta T cell lineage cells. The development of both gammadelta T cells and DN alphabeta T cells is poorly understood; therefore, we thought it would be important to identify the immediate precursors of
Protein kinase C (PKC) plays a prominent role in immune signaling, and the paradigms for isoform selective signaling are beginning to be elucidated. Real-time microscopy was combined with molecular and biochemical approaches to demonstrate a role for PKC-epsilon in Fcgamma receptor (FcgammaR)-dependent phagocytosis. RAW 264.7 macrophages were transfected with GFP-conjugated PKC isoforms, and GFP m
Measurements are presented of inclusive charm and beauty cross sections in e(+)p collisions at HERA for values of photon virtuality 12 <= Q(2) = 60 GeV2 and of the Bjorken scaling variable 0.0002 <= x <= 0.005. The fractions of events containing charm and beauty quarks are determined using a method based on the impact parameter, in the transverse plane, of tracks to the primary vertex, as measured
In the offshore industry, reliability of installed equipment is of paramount concern due to safety, environmental and economic consequences. The costs of unplanned shutdowns and maintenance have high economic implications and are of increasing importance with tighter profit margins. Reliability is therefore of significance when selecting equipment model and brand. This report presents a survey of
Small synthetic ligands for protein purification have become increasingly interesting with the growing need for cheap chromatographic materials for protein purification and especially for the purification of monoclonal antibodies (mAbs). Today, Protein A-based chromatographic resins are the most commonly used capture step in mAb down stream processing; however, the use of Protein A chromatography
BALTHAZAR BERLING - LE FAIT DU CORPS (BARTHÉLÉMY) LOUI KUHLAU - THE MUNDANE EGG In language you divide, categorize and combine. As words enters your language they create parameters in a spectrum, in which you previously didn’t make any distinctions. As you come into being without a language, the first period of life is lived in a continuous spectrum. A world where everything is one. Your senses co
https://www.khm.lu.se/balthazar-berling-loui-kuhlau - 2026-05-07
Healthy eye lenses are transparent and flexible, able to adapt shape in order to focus on far away and close-by objects. With age, however, this flexibility is lost, leading to a condition known as presbyopia. This vision disorder where close-by objects appear blurred commonly starts around the age of 40. The aim of this thesis is to elucidate the molecular origin of the gradual hardening of the c
Vart fjärde år, i valtider, uppstår en viss typ av kommunikation då och enbart då. Valaffischer trycks än idag i stora upplagor och sätts upp vid valda platser i hela Sverige, vilket leder till en stor exponering hos invånarna. Denna stora uppvisning har dock inte lett till någon större forskningsinsats på valaffischer, utan det finns ett mycket smalt utbud av studier av svenska valaffischer. ForEvery fourth year at, during elections, a certain type of communication appears. Election posters are still today printed in large quantities and placed at locations all throughout Sweden, which entails a large exposure to the inhabitants. Yet, this display has not lead to a great amount of research on election posters, but there is a small number of studies of Swedish election posters. Research
The emergence of blockchain technology enables entrepreneurs to raise capital in an innovative way, by addressing a crowd of online investors without the need for an intermediary. This phenomenon is known as token sales, and it may have the potential to revolutionize entrepreneurial finance. However, information asymmetry is particularly severe in this context, and the need for entrepreneurs to se
On July 2018, for the first time in modern Mexican history, a leftist candidate won the presidential elections in Mexico. With large promises on the eradication of corruption and ending social injustice, Andrés Manuel López Obrador and his party secured both the presidency and both chambers of the Mexican Congress. This paper inquires into to what extent a president belonging to the political left
