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Objectives. The EGFR is expressed in malignant ovarian tumor tissue, and tissue content of EGFR has been directly associated with poor prognosis in patients with ovarian cancer. The uPA system plays a role in pericellular proteolysis, cell migration, invasion, and is over-expressed in ovarian cancer. This study explored the effects of EGF on uPAR expression in the ovarian cancer cell line OVCAR-3.
Popular Abstract in Swedish Blodet innehåller några av de mest grundläggande komponenterna för mänskligt liv. Med hjälp av hjärtats pumpkraft transporterar röda blodkroppar ut syre från lungorna till de mest avlägsna delarna av kroppen via gradvis tunnare blodkärl. Livshotande blödningar stoppas via blodplättarnas koagulerande förmåga och läkande egenskaper, medan de vita blodkropparna bekämpar inHematopoietic stem cells (HSCs) are defined by their capacity to self-renew and differentiate into all hematopoietic cell lineages. Postnatally, HSCs reside predominantly in the bone marrow and are relatively rare, but important cells because of their therapeutic potential in bone marrow transplantation protocols and in their involvement in the origin of certain leukemias. To study how various gen
Background: Depression is linked with alexithymia, anxiety, high HbA1c concentrations, disturbances of cortisol secretion, increased prevalence of diabetes complications and all-cause mortality. The psycho-educational method 'affect school with script analysis' and the mind-body therapy 'basic body awareness treatment' will be trialled in patients with diabetes, high HbA1c concentrations and psych
Savanner är ett landskap med både träd och gräs som skapar en miljö som varken är skog eller gräsmark. Savanner tar upp cirka en sjättedel av världens totala landyta och de har på grund av detta en stor betydelse för den globala kolbalansen. De flesta savanner har två distinkta säsonger, en regnperiod då vegetationen grönskar samt en period med torka utan nederbörd. Detta gör att förändringar i deSavannahs are land areas where grass and trees co-exists to create a landscape that is neither a grassland nor a forest. It is estimated that savannahs cover approximately one sixth of the global land surface. They also play an important role in the global carbon cycle due to their total size. Most savannahs are characterized with two distinct seasons, one dry season and one wet season where a maj
Background: Domestic violence during pregnancy is not only a severe public health issue that jeopardizes maternal and foetal health but also violates human rights. The aim was to explore the prevalence and incidence of domestic violence among pregnant women, in the southwestern region of Scania in Sweden, and their experience of a history of violence. In addition, to explore the association betwee
Introduction: In wood-dwelling fungus-farming weevils, the so-called ambrosia beetles (Curculionidae: Scolytinae and Platypodinae), wood in the excavated tunnels is used as a medium for cultivating fungi by the combined action of digging larvae (which create more space for the fungi to grow) and of adults sowing and pruning the fungus. The beetles are obligately dependent on the fungus that provid
Context:The cardiac natriuretic peptides are involved in blood pressure regulation, and large cross-sectional studies have shown lower plasma levels of N-terminal pro-natriuretic peptide levels [N-terminal atrial natriuretic peptide (N-ANP) and N-terminal brain natriuretic peptide (N-BNP)] in patients with insulin resistance, obesity, and diabetes.Objective:In this study, we prospectively tested w
The effect of the pineal indole hormone melatonin on the life span of mice, rats and fruit flies has been studied using various approaches. It has been observed that in female CBA, SHR, SAM and transgenic HER-2/neu mice long-term administration of melatonin was followed by an increase in the mean life span. In rats, melatonin treatment increased survival of male and female rats. In D. melanogaster
Den svenska riksdagen har höga ambitioner om att utveckla den förnyelsebara energin i allmänhet och vindkraften i synnerhet. Nationella energi- och miljöpolitiska mål har antagits för att förenkla etableringar och således skapa förutsättningar för en utveckling av vindkraften i Sverige. Ambitionerna är högt ställda men politiska ställningstagande kräver verkställighet och resultatet av det finner The Swedish Parliament sets high ambitions in order to develop renewable energy in general and wind energy in particular. National energy and environmental policies have been adopted to facilitate wind power establishments and thus create conditions for development of wind power in Sweden. The ambitions are high but political positions requires enforcement and the result of the objectives are foun
Abstract Breast cancer is the most commonly diagnosed type of cancer in women worldwide. Inherited or acquired aberrations of genes in DNA damage repair, cell cycle checkpoint, apoptosis, and growth signaling pathways are responsible for the generation of breast cancer. Recently, increasing evidence shows that signaling pathways can be highly interconnected and are interacting with each other rat
Syftet med föreliggande uppsats är att undersöka domstolsprövningen av förvaltningsbeslut och hur dess roll i det konstitutionella systemet har förändrats till följd av europeiseringen av den nationella rätten. Uppsatsen inleds med ett kapitel om de europarättsliga kraven på domstolsprövning av förvaltningsbeslut. Därefter ägnas ett kapitel åt utvecklingen av den svenska förvaltningsprocessen. FörThe aim of this study is to examine the judicial review of administrative decisions and how its function in the constitutional system has changed following the Europeanization of national law. The essay begins with a chapter on judicial review of administrative proceedings according to the European law. Then a chapter follows on the Swedish administrative procedural law and its development. To cla
Thomas Quick, numera Sture Bergwall, har kallats Sveriges värste seriemördare. Nu krackelerar den bilden. Sedan Thomas Quick tog tillbaka sina erkännanden har han praktiskt blivit friad från samtliga åtta mord han blivit dömd för. Syftet med framställningen är att utreda hur domen gällande Appojaurefallet kunde rämna bara för att den tilltalade Thomas Quick tog tillbaka sitt erkännande. Mer konk
Syftet med denna framställning är att belysa och utreda problem som kan finnas med den nuvarande regleringen kring avtal om vårdnad och särskilt beträffande FB 6:6 2 st. som gäller avtal om gemensam vårdnad. FB 6:6 2 st. stadgar att avtal om gemensam vårdnad ska godkännas av socialnämnden om det inte är uppenbart att avtalet är oförenligt med barnets bästa. Enligt FB 6:6 1 st. är det möjligt för The purpose of this essay is to highlight and study complications that may exist with the current regulation of agreements regarding legal custody, and especially Children and Parents’ Code (Föräldrabalken 1949:381) 6:6 second paragraph which concern agreements regarding joint custody. According to Children and Parents’ Code 6:6 first paragraph it is possible for parents to make an agreement con
Denna uppsats hade som syfte att besvara frågorna om huruvida status som rättighetsbärare tillkommer ofödda människor, samt om gällande regleringar är tillräckliga för att skydda ofött liv. Undersökningen om rättighetsbärarstatus skedde inom ramen för rätten till liv, eftersom denna rättighet förutsattes vara den mest relevanta för ofödda människor. Uppsatsen undersökte först internationella mänsThis essay set out to answer the questions whether a status as rights-bearer is acknowledged for unborn human beings, and if the regulations in place are adequate in order to protect unborn life. Rights-bearer status was explored within the scope of the right to life, as this right was assumed to be the most relevant for unborn humans. The essay first examined international human rights law, focu
The Roan peninsula in western Norway, Vestranden, is known for exposing one of the deepest parts of the Scandinavian Caledonian orogen, similar to the Western Gneiss Region. Throughout the Roan area, eclogites and high-pressure granulite- and amphibolite-facies gneisses occur, associated with supracrustal rocks including marbles, calc-silicate rocks and amphibolites. Although extensive research ha
Title: Accelerating Service Innovation with Global Account Management – A Case Study at a Manufacturing MNC Author: Emma Malmström – Master of Science in Industrial Engineering and Management, em.malmstrom@gmail.com Tutors: Malin Olander Roese – PhD Researcher, Department of Design Sciences, Faculty of Engineering, Lund University and Susanna Bill – PhD Student, Department of Design Sciences, Fa
Purpose: The purpose of this study was two-fold. First, we aimed to develop a framework concerning how to directly and indirectly control discrimination in the workplace using Man- agement Control Systems (MCS). Second, we wanted to examine whether this framework is practically applicable in multinational enterprises (MNE). Methodology: The first part of the purpose was achieved through conduc
Improving teamwork has become a major safety goal for healthcare organizations. Audit tools currently available are useful, but they remain inadequate because they are reactive and fail to provide context for “the interaction between people and the operational context (i.e., organizational, regulatory and environmental factors) within which people discharge their operational duties” (Maurino, 2005
Introduction: In recent years, the e-commerce industry has developed at extremely high speed all over the world and becomes the sunrise industry. Besides, there is a megatrend that customers are pursuing better experience along the whole shopping journey. Statistics show that good reverse logistics service is an efficient way to improve customers satisfaction level. Among the reverse logistics, th
Den samiska ursprungsbefolkningens traditionella territorium breder ut sig över delar av Sverige, Norge, Finland och Ryssland. Samisk kultur är starkt kopplad till rennäringen, som kräver vidsträckta och sammanhängande marker där renen ostörd kan få tillgång till naturbete. Den här uppsatsen undersöker nuvarande möjligheter för samer i Sverige att påverka beslutsprocesser rörande användning av marThe traditional territory of the indigenous Sami people stretches into Sweden, Norway, Finland and Russia. Sami culture is strongly connected to reindeer husbandry, which requires vast and coherent land where the reindeer can access natural pasture without disturbances. This thesis examines present possibilities for Sami in Sweden to impact decision-making processes regarding use of land and natur
