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Signs of Hyperinflation and Ventilation Heterogeneity in Individuals With Severe Alpha-1-Antitrypsin Deficiency at the Age of 42

Background: Severe alpha-1-antitrypsin deficiency (AATD) is a known risk factor for early development of emphysema and COPD. By the Swedish national screening program within the years 1972–74 a cohort of individuals with severe AATD (PiZZ) was identified and regularly followed up. The aim of this study was to investigate alveolar volume (VA) and the ratio VA/Total lung capacity (VA/TLC) for the de

Estimating the lake storage capacity on the Tibetan Plateau using satellite altimetry and imagery data : a comparative analysis of water volume change methods

Compared to lake area and water level, lake storage capacity more intuitively reflects regional climate changes. In this study, we first derived lakebed elevation profiles for individual ICESat-2 tracks based on the underwater stratification of laser photons, then integrating all valid elevation tracks within the water body to interpolate the bathymetry. On this basis, we calculated the capacity a

Septic arthritis score (SAS) - a novel clinical prediction model for the probability of septic arthritis in the adult native knee

BACKGROUND: Patients presenting with an acutely painful swollen joint represent a diagnostic challenge. We aimed to develop a clinical prediction model for septic arthritis (SA) in the adult native knee.METHODS: We screened all synovial cultures in south Sweden in 2020 and 2021. We included cultures taken in the emergency department from adults' native knees where SA was considered a differential

Våldtagen eller inte? En studie kring professionellas syn på den våldtagna kvinnan och den rättsprocess hon genomgår

Many sexual crime matters are in a difficult position when it comes to proof, where it's word against word between the parties. However, the legislation states that it's the offender's actions that are to be in focus for the judicial judgement, but often the focus is on the woman, whether she said no and how she acted in that particular situation (Sutorius & Kaldal, 2003). The pur

Barriers to Provide Cross Border Services/Case Study Nordea

There is an increase of financial integration, which can be seen in recent mergers of banks, financial institutions etc. in the European Union especially in the Nordic countries. However there are some weaknesses in providing consumers cross border services in the sector of banking, such as cross border bank account transfer of payments. The existing transaction costs do not encourage cross border

Determinants of lung function and airway hyperresponsiveness in asthmatic children

Background: Asthma patients exhibit an increased rate of loss of lung function. Determinants to such decline are largely unknown and the modifying effect of steroid therapy is disputed. This cross-sectional study aimed to elucidate factors contributing to such decline and the possible modifying effect of steroid treatment. Methods: We analyzed determinants of lung function and airway hyperresponsi

Substitution reactions of [Pt(dien)Cl](+), [Pt(dien)(GSMe)](2+), cis-[PtCl2(NH3)(2)] and cis-[Pt(NH3)(2)(GSMe)(2)](2+) (GSMe = S-methylglutathione) with some sulfur-bonding chemoprotective agents

Sulfur-containing compounds are used as rescue agents to protect normal tissue from the toxic side effects of cis-[PtCl2(NH3)(2)] (cisplatin) without affecting its anti-tumour activity. Reactions of the model complexes [Pt(dien)Cl](+) (1) and [Pt(dien)(GSMe)](2+) (2) (GSMe = S-methylglutathione) with the rescue agents glutathione (GSH), thiourea, thiosulfate, and diethyldithiocarbamate (DDTC) have

Pancreatitis-Associated Pulmonary Injury

Popular Abstract in Swedish Akut bukspottkörtelinflammation (akut pankreatit ? AP) är en akut inflammation som kan resultera i en självdestruktiv process i bukspottkörteln. 70-80 % av fall med AP klassificeras som lätta-måttliga och är självbegränsande, medan cirka 20 % klassas som svåra och karakteriseras av utvecklingen av nekros (vävnadsdöd) i bukspottkörteln och omkringliggande vävnad, utvecklIn acute pancreatitis (AP), lung injury is an early occuring and important part of the multiple organ dysfunction syndrome. The mechanisms underlying the development of lung injury though still largely remains unclear. The aim of the present study was to study mechanisms of the systemic and secondary pulmonary inflammation and injury, with an emphasis on the involvement of immune cells, inflammato

The cost-effectiveness of risedronate in the treatment of osteoporosis: an international perspective

Introduction: Risedronate, a bisphosphonate for treatment and prevention of osteoporosis, has been shown in several clinical trials to reduce the risk of fractures in postmenopausal women with osteoporosis. The cost-effectiveness of risedronate treatment has previously been evaluated within different country settings using different model and analysis approaches. The objective of this study was to

Breaking the boundaries of careers. A study of the mobility effects of a program for career councelling

In this paper a study of a career planning project launched by the Swedish National Tax Board is reported. The project, named Propeller, was initiated in 1998 as a joint endeavour among three agencies: the Swedish National Tax Board, the Regional Stockholm Tax Office and the Enforcement Authority. The intention was to create a common micro labour market in order to encourage employees to become mo

Det anglosaxiska Köpenhamnsevangeliariet : Det kongelige bibliotek, Gl. Kongl. Saml. 10 2º

Popular Abstract in Swedish Köpenhamnsevangeliariet skrevs och illuminerades i England omkring år 1000, och intar en viktig position i konsthistorien genom sina ikonografiska likheter med det 300 år äldre Lindisfarneevangeliariet. I föreliggande avhandling behandlas handskriften i sin helhet med avseende på dess framställning och senare historia, men den huvudsakliga analysen rör bildernas stilistThe subject of this thesis is the Copenhagen Gospel Book , written and illuminated in England c 970 with additions from c 1020. The thesis is divided into three main parts focusing on different aspects of the manuscript. The first part deals with problems concerning provenance, palæography, later additions and the physical architecture of the manuscript. The author questions the opinion that the m

Sleep disturbance in association with elevated pulse rate for prediction of mortality--consequences of mental strain?

OBJECTIVES: Sleep deprivation has experimentally been shown to adversely influence glucose metabolism, endocrine function and sympathovagal balance in young men without known serious disease. We investigated the impact of sleep problems and resting heart rate in a large sample of self-reported, healthy middle-aged men and women on long-term mortality. METHODS: In all 22,444 men and 10,902 women pa

Kvinnors försörjningsrum : Hegemonins förvaltare och murbräckor

Popular AbstractAvhandlingen är en feministisk analys av regionalpolitiken som möjliggörare för kvinnor som vill försörja sig på landbygden som egna företagare. Fokus i studien är kvinnor som ville men inte ansåg sig ha eller fick möjlighet driva sina företagsidéer vidare och därför avvecklade dem på ett tidigt stadium. I intervjuer redogör ett antal kvinnor för sina upplevelser av att arbeta för This thesis deals with questions concerning the different strategies women adopt in order to support themselves when they become unemployed in rural areas. One strategy is to start a business of one's one, a strategy supported and called for by the Swedish Government, especially during the 1990s economic recession. Another important factor was the Swedish membership in the EU that demanded cutback

Outcome of cataract surgery in eyes with diabetic retinopathy : a Swedish national cataract register report

Purpose: To analyse if patients with diabetic retinopathy (DR) subjected to cataract surgery differ in outcome compared to patients without DR with regard to best-corrected visual acuity (BCVA), deviation from target refraction, intraoperative difficulties and risk of complications. Methods: A register-based study from the Swedish National Cataract Register (NCR) during the years 2015–2017 includi

Decentralized ventilation unit for window frame integration

Swedish National Board of Housing, Building and Planning reported in "Energi i bebyggelsen"that 80 % of the detached houses in Sweden were under-ventilated, and had a flow of 0.23 l/(s·m2) on average instead of, by the code, required 0,35 l/(s·m2). Well known concerns here are lacking indoor environmental quality and a risk of moisture problems in certain rooms and in the envelope. The naturally v

Farmland birds on forest clear-cuts : Liked by some, avoided by others

Many bird species typical to farmland have declined in numbers in recent decades. Some farmland bird species occur outside farmland in other open man-made habitats, such as forest clear-cuts. Given that in Sweden the total area of clear-cuts (5–6 %) almost equals that of farmland (8 %), clear-cuts have the potential to be an important habitat for some farmland birds. We investigated how bird commu

Linkages between rainfed cereal production and agricultural drought through remote sensing indices and a land data assimilation system : A case study in Morocco

In Morocco, cereal production shows high interannual variability due to uncertain rainfall and recurrent drought periods. Considering the socioeconomic importance of cereal for the country, there is a serious need to characterize the impact of drought on cereal yields. In this study, drought is assessed through (1) indices derived from remote sensing data (the vegetation condition index (VCI), tem

Does community-based health insurance protect women from financial catastrophe after cesarean section? A prospective study from a rural hospital in Rwanda

Background: The implementation of community-based health insurance in (CBHI) in Rwanda has reduced out of pocket (OOP) spending for the > 79% of citizens who enroll in it but the effect for surgical patients is not well described. For all but the poorest citizens who are completely subsidized, the OOP (out of pocket) payment at time of service is 10%. However, 55.5% of the population is below the

Intensive care medicine in Europe : Perspectives from the European Society of Anaesthesiology and Intensive Care

BACKGROUND Anaesthesiology represents a rapidly evolving medical specialty in global healthcare, currently covering advanced peri-operative, pre-hospital and in-hospital critical emergency management (CREM), intensive care medicine (ICM) and pain management. The aim of the European Society of Anaesthesiology and Intensive Care (ESAIC) is to develop and promote a coordinated interdisciplinary and m

The Application of a Wildfire Evacuation Tool to Swedish locations

WUI-NITY is a computer modelling program for wildfire evacuation simulations. This thesis examines the applicability of WUI-NITY to locations in Sweden. The program was tested at example locations representing the Swedish landscape. The objective of this work was both to examine the application of the model, but also to produce a process by which the model might be applied – highlighting challenge