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Abstract. In previous work we have studied the effects of electromagnetic fields upon the promotion of growth of tumours from two different rat glioma cell lines, RG2 and N32, inoculated in the brains of Fischer 344 rats. No promotions of tumour growth due to the EMF could be demonstrated in large series of animals as compared to their matched controls. In the present study we have utilized a newl
Chondroitin sulfate (CS) and dermatan sulfate (DS) are expressed in significant amounts in the brain and play important roles in the development of the central nervous system in mammals. CS and DS structures are often found in a single CS/DS hybrid chain. The L-iduronic acid (IdoA)-containing domain, which defines a DS-type domain, appears key to the biological functions of the CS/DS hybrid chain.
OBJECTIVES: To investigate the distribution of the transient receptor potential (TRP) A1 ion channel in the rat urinary bladder, and to study the effects of hydrogen sulfide (H(2)S) and known TRPA1 activators on micturition in conscious rats and on heterologously expressed ion channels. METHODS: The expression of TRPA1 in urinary bladder was studied with fluorescence immunohistochemistry and real-
Background: Irritable bowel syndrome (IBS) and gastrointestinal (GI) dysmotility disorders have a similar clinical picture, although dysmotility disorders require the attention of a specialist. Patients with primary Sjogren's syndrome (pSS) have also been described to suffer from IBS-like symptoms. No objective marker is available to distinguish between the patients. A visual analogue scale has be
Popular Abstract in Swedish Bakgrund En till fem procent av de patienter som genomgår öppen hjärtkirurgi får en efterföljande infektion i operationssåret och bröstbenet. Infektionen kan leda till allvarliga komplikationer såsom blodförgiftning, organsvikt och i värsta fall till att patienten avlider. De traditionella metoder som används för att behandla den här typen av infektion har visat sig haNegative pressure wound therapy (NPWT) has been widely adopted for the treatment of deep sternal wound infections due to its excellent clinical outcome. However, the mechanisms of action and effects on hemodynamics have not been thoroughly elucidated. The aims of the work presented in this thesis were, therefore, to examine the effects of NPWT on sternotomy wounds and on the intrathoracic organs.
We assessed age-related differences in adults in familiarization to treadmill walking within virtual environments (VE), and examined whether treadmill walking after familiarization resembles overground walking. Seventeen younger and 17 older adults walked at preferred speed on an overground walkway and afterwards walked at the same speed for 20 min on a treadmill coupled to a VE. A motion capture
Background: Potato late blight caused by the oomycete pathogen Phytophthora infestans can lead to immense yield loss. We investigated the transcriptome of Solanum tubersoum (cv. Desiree) and characterized the secretome by quantitative proteomics after foliar application of the protective agent phosphite. We also studied the distribution of phosphite in planta after application and tested transgeni
Moraxella catarrhalis is a common pathogen found in children with upper respiratory tract infections, and in patients with chronic obstructive pulmonary disease during exacerbations. The bacterial species is often isolated together with Streptococcus pneumoniae and Haemophilus influenzae. Outer membrane vesicles (OMV) are released by M. catarrhalis and contain phospholipids, adhesins, and immunomo
Popular Abstract in Swedish Bröstcancer är den vanligaste maligna sjukdomen hos kvinnor i världen. Årligen insjuknar mer än 7300 kvinnor i Sverige, vilket innebär nästan 30 % av all kvinnlig cancer. Mer än 80 000 kvinnor i Sverige är friska efter att ha blivit behandlade för bröstcancer, och cirka 3000 kvinnor lever med återfall av sjukdomen. Prognosen har förbättrats de senaste decennierna, delviRadiotherapy (RT) after mastectomy has been part of the treatment for early breast cancer since the 1940s. The treatment reduces the risk of loco-regional recurrences, but implies risk of late side effects that can begin decades after RT. Aims of the thesis were: - To analyse the long term effects of postmastectomy radiotherapy and systemic treatment for 1100 stage II breast cancer patients in t
The indoor climate in buildings has changed in the last decade due to more efficient climatic systems, floor heating systems and larger open floor areas with more natural light. All this has induced increasing ranges of relative humidity between different seasons. Also with decreasing relative humidity (in the winter 30-50% RH, in the summer 70-90% RH), floor-heating systems increase the temper
This thesis is about avenues (tree-lined roads – in Swedish alléer). Avenues are a characteristic landscape element in many parts of Scania. This is an object created by man with a clear visual effect in the landscape. The avenue is also something which is both nature and culture, a man-made object from nature. The purpose of the thesis is to describe, analyse and discuss the historical geograph
Signaling of platelet derived growth factor receptor alpha (PDGFRA) is critically involved in the development of gliomas. However, the clinical relevance of PDGFRA expression in glioma subtypes and the mechanisms of PDGFRA expression in gliomas have been controversial. Under the supervision of morphological diagnosis, analysis of the GSE16011 and the Repository of Molecular Brain Neoplasia Data (R
Objective. This study aimed to survey current Swedish practices for performing and handling transrectal ultrasound-guided prostate biopsies. Material and methods. A Swedish Urology Network (SUNe) was organized for the distribution of information, survey studies and research collaborations. A web-based questionnaire was distributed to the members in 2011. Results. In this first SUNe survey, 137 (91
Natural disturbances play a key role in ecosystem dynamics and are important factors for sustainable forest ecosystem management. Quantitative models are frequently employed to tackle the complexities associated with disturbance processes. Here we review the wide variety of approaches to modelling natural disturbances in forest ecosystems, addressing the full spectrum of disturbance modelling from
For construction in rock a thorough pre-investigation is important in order to avoid unforeseen conditions which may delay the work. It is crucial to remember the results from this investigation in the further work, and use the experience from the construction to update the geological prognosis and reduce the uncertainties. Different geophysical methods have proved valuable tools in such investiga
Physical properties of aqueous solutions of hydrophobically modified crosslinked polyacrylic acids change quite extensively as the polymer is charged up. A study is carried out concerning the similarities between two polymer ionization processes, that is, by pH increment and anionic surfactant addition. The two processes charge the polymer by distinctly different mechanisms. At sufficiently high p
Air pollution is a major environmental and health problem globally, with traffic emissions being a significant source of many pollutants. The aim of this study is to investigate whether the levels of nitrogen dioxide (NO2), ground-level ozone (O3) and coarse particles (PM10) in air changed during the covid-19 pandemic in Sweden, and whether the change varied between urban and rural areas and depen
The start-up company LEVTEK is launching a new ultralight electric utility vehicle called the LEVKART. The Levkart uses a combination of robotics and AI-technology to offer semi-autonomous or autonomous riding and usage. The purpose of the vehicle is to serve as an alternative to cargo bikes and electric scooters designed for easy usage and as a more sustainable option to fossil-based transport. T
För att kunna handskas med de stigande stressnivåerna hos skolelever är det viktigt att skapa en välfungerande lärandemiljö. Detta kan till exempel göras med olika verktyg och ett av dem är Woof Technologies ApS platform WOOF som kan användas som ett hjälpmedel för lärare i grundskolan för att mäta och arbeta med elevers trivsel och välmående i en klass. Syftet med detta arbete är att analysera ocIn order to deal with the rising stress levels of pupils, it is important to create a well-functioning learning environment. This can for example be done with various tools, one of them being Woof Technologies ApS platform WOOF which can be used as an aid for teachers in elementary school to measure and work with students' well-being in class. The purpose of this thesis is to analyze and eval
Cities play a crucial role in mitigating climate change, yet reducing transportation emissions remains a challenge. Achieving decarbonization in the transportation sector requires systemic transformations across society. However, there is still a limited understanding of how transitions within transportation can be achieved, and further insight is needed to guide cities in driving transformative c
