Filtyp
Our understanding of fundamental organismal biology has been disproportionately influenced by studies of a relatively small number of ‘model’ species extensively studied in captivity. Laboratory populations of model species are commonly subject to a number of forms of past and current selection that may affect experimental outcomes. Here, we examine these processes and their outcomes in one of the
OBJECTIVE In this study, we aimed to explore the mechanism by which TCF7L2 rs7903146 risk allele confers susceptibility to impaired glucose tolerance (IGT) or type 2 diabetes (T2D) in obese adolescents. RESEARCH DESIGN AND METHODS The rs7903146 variant in the TCF7L2 gene was genotyped in a multiethnic cohort of 955 youths. All subjects underwent an oral glucose tolerance test with the use of the O
Titan, Demon and Genius in the Poetical Work of Mihai Eminescu is a book that furthers on the interpretation of the most representative Eminescu’s poems and also of his lyrical theatre. Besides, a special chapter is dedicated to the cultural context of the second half of the 19th century and another one records the literary works inspired by Eminescu’s works and personality throughout the 20th cen
Introduction Reporting estimated glomerular filtration rate (eGFR) instead of serum concentrations is advised in current guidelines. Most creatinine-based eGFR equations for children require height, a parameter not readily available to laboratories. Combining height-dependent creatinine- and cystatin C-based eGFR improves performance. Recently, a height-independent creatinine-based eGFR equation h
Non-myelinated C-fibre responses during sympathetic trunk stimulation were studied in rabbit common peroneal nerve 2 weeks after the nerve had been subjected to compression at 400 mmHg for 30 min. Our previous studies have demonstrated that during sympathetic trunk stimulation the compound action potential of uninjured somatic C-fibres is characterized by a reduced amplitude and an increased laten
BACKGROUND: Klinefelter syndrome (KS) is the most common sex chromosome disorder. The genetic background is the extra X chromosome. Venous thromboembolism (VTE) has been observed among KS patients. The aim of the present study was to examine whether KS is associated with VTE.METHODS AND RESULTS: We followed up all hospital in- and outpatients (N=1085) in Sweden with a diagnosis of KS between Janua
År 2001 deklarerade den tanzaniska regeringen den första Primary Education Development Plan och därmed avskaffades den tidigare obligatoriska skolavgiften för grundskolan. I och med avskaffandet av skolavgiften förväntades andelen barn i grundskola att öka. Syftet med avhandlingen är att förstå hur reformen och dess fokus på avskaffandet av skolavgiften har påverkat föräldrars och vårdnadshavaresIn 2001, the first Primary Education Development Plan declared that the previous obligatory primary education fee was to be abolished in Tanzania. This was an attempt to increase the access to public primary education for all children. This thesis aims to understand how the reform and its focus on the abolition of school fee influences parents’ and caregivers’ support for primary education and imp
Seed orchards function as the primary source of high-quality seeds for reforestation in many European countries, but their seed yields can be severely reduced due to seed- and cone-feeding insects. We evaluated various parameters of pheromone-based mating disruption for control of the moths Cydia strobilella and Dioryctria abietella, which are major pests in European Picea abies seed orchards. We
The balance between the availability of energy and nutrients is decisive for the growth and survival of organisms. Here, we evaluated how energy, in this study expressed as total carbon (TC), is lost along the land to ocean aquatic continuum (LOAC) in relation to nutrients, i.e., total phosphorus (TP), total nitrogen (TN), total iron (TFe), and dissolved silica (DSi). For the evaluation, we used d
BACKGROUND: Impaired antiviral interferon expression may be involved in asthma exacerbations commonly caused by rhinovirus infections. Allergy is a known risk factor for viral-induced asthma exacerbation, but little is known whether allergens may affect interferon responses.OBJECTIVE: Our hypothesis is that house dust mite (HDM) impairs viral stimulus-induced antiviral signalling.METHODS: Experime
Purpose: In Parkinson’s disease (PD), pathological microstructural changes occur that may be detected using diffusion magnetic resonance imaging (dMRI). However, there are few longitudinal studies that explore the effect of disease progression on diffusion indices. Methods: We prospectively included 76 patients with PD and 38 healthy controls (HC), all of whom underwent diffusion kurtosis imaging
This paper considers the long-term effects of smoking on disability retirement in Sweden. Smoking is known to have damaging effects on health, but there is limited evidence on how the effects of smoking translate into worse labour market outcomes, such as the inability to work. In contrast to the few previous studies on smoking and disability retirement, we use a large population sample with regis
The human host defense peptide, LL-37, is an important player in the first line of defense against invading microorganisms. LL-37 and its precursor, hCAP18, have been detected in unstimulated whole saliva but no reports showing hCAP18/LL-37 in isolated, parotid, and/or submandibular/sublingual saliva have been presented. Here, we measured the levels of hCAP18/LL-37 in human parotid and submandibul
The signal crayfish (Pacifastacus leniusculus) was introduced to Sweden in 1960, and it has a high commercial and recreational value, but it may also have negative effects on native ecosystems. To better predict how climate warming will affect population dynamics of this cool-water crayfish, we explored the role of temperature and density dependence as explanatory factors of the subsequent years’
A research-based understanding of permafrost distribution at a sufficient spatial resolution is important to meet the demands of science, education and society. We present a new permafrost map for Norway, Sweden and Finland that provides a more detailed and updated description of permafrost distribution in this area than previously available. We implemented the CryoGRID1 model at 1km2 resolution,
In continental margin basins, the hydrogeological setting is complex due to transgression/regression events that removed old sediments in the basin and formed new geologic units. Due to the geological complexity, the use of vertical electrical sounding has proven to be insufficient for groundwater explorations. The lack of understanding the geological underground has resulted in many boreholes wit
Objective: This study aims to illuminate expectant first-time fathers’ experiences of participation during pregnancy in three Nordic countries. Background: Fathers’ participation in pregnancy is associated with improved health for the family as a whole. Research so far has primarily explored fathers’ participation in pregnancy within health care settings. It is important to know more about how fa
In the present work, the antimicrobial activity of different pressurized liquid extracts obtained from Haematococcus pluvialis microalga was tested against several microorganisms of importance for the food industry (Escherichia coli, Staphylococcus aureus, Candida albicans and Aspergillus niger). Extractions were performed with hexane and ethanol at four different temperatures (50, 100, 150 and 20
In this work, a new copolymer synthesized in our laboratory is used as physically adsorbed coating for capillary electrophoresis (CE). The copolymer is composed of ethylpyrrolidine methacrylate (EPyM) and methylmethacrylate (MMA). The capillary coating is easily obtained by simply flushing into the tubing an EPyM/MMA solution. It is demonstrated that the composition of the EPyM/MMA copolymer toget
Aims: The aim of the study was to compare outcomes in unfractionated heparin (UFH) and bivalirudin-treated patients undergoing primary percutaneous coronary intervention (PPCI). Methods and results: This observational study contained 20,612 PPCI patients treated with either UFH monotherapy or bivalirudin with or without concomitant UFH. Patients with oral anticoagulant or glycoprotein IIb/IIIa inh
