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Composites of TiC and TiB2 were prepared by self-propagating high-temperature synthesis (SHS). Two routes were attempted; from the elements and from a mixture of anatase, boron oxide, graphite and magnesium. The reactions were monitored in situ by synchrotron X-ray diffraction ( lambda = 0. 26102 Angstrom). The powder mixtures were compacted as cylindrical pellets and upon ignition diffraction pat

Tapasin (tpn), an essential component of the MHC class I (MHC I) loading complex, has a canonical double lysine motif acting as a retrieval signal, which mediates retrograde transport of escaped endoplasmic reticulum (ER) proteins from the Golgi back to the ER. In this study, we mutated tpn with a substitution of the double lysine motif to double alanine (GFP-tpn-aa). This mutation abolished inter

ABSTRACT: BACKGROUND: The endoglycosidase EndoS and the cysteine proteinase SpeB from the human pathogen Streptococcus pyogenes are functionally related in that they both hydrolyze IgG leading to impairment of opsonizing antibodies and thus enhance bacterial survival in human blood. In this study, we further investigated the relationship between EndoS and SpeB by examining their in vitro temporal

Background Following surgical repair of aortic coarctation (CoA) there is a risk for restenosis (reCoA), particularly in the first year of life. It was the aim of this study to identify reCoA risk factors by analyzing postoperative pre-discharge echocardiograms. Methods Retrospective analysis of echocardiograms of children born operated for CoA in Sweden 2011-2017. Results 253 children were includ

HCV infection is a major risk factor for liver cancer and liver transplantation worldwide. Overstimulation of host lipid metabolism in the liver by HCV-encoded proteins during viral infection creates a favorable environment for virus propagation and pathogenesis. In this study, we hypothesize that targeting cellular enzymes acting as master regulators of lipid homeostasis could represent a powerfu

Background: Screening across a multitude of normal and malignant tissues revealed an enhanced expression of lymphocyte antigen 6 superfamily member D (LY6D) in squamous epithelium and urothelium, as well as in malignancies derived therefrom. The aim of this study was to further delineate the protein expression of LY6D in urothelial bladder cancer, with particular attention to its relationship with

BACKGROUND/AIMS: The aim of this study was to develop a risk model for intraoperative complication (IC) during cataract surgery, defined as posterior capsule rupture and/or zonular dehiscence, and to include previous intravitreal therapy (pIVT) in the model.METHODS: This retrospective register-based study covered patients reported to the Swedish National Cataract Register (SNCR) between 1 January

Background: To become a parent of a child who is born small for gestational age can lead to challenges in addition to the newly acquired parenting role. There is currently a lack of knowledge regarding parents' experiences of having a child born small for gestational age. Purpose: The purpose of this study was to describe the experience of becoming a parent of a child small for gestational age Des

Treatment of melanoma with a BRAF inhibitor (BRAFi) frequently initiates development of BRAFi resistance, leading to increased tumor progression and metastasis. Previously, we showed that combined inhibition of elevated WNT5A and IL-6 signaling reduced the invasion and migration of BRAFi-resistant (BRAFi-R) melanoma cells. However, the use of a combined approach per se and the need for high inhibi

Grocery retail is going through a rapid shift. Consumers now expect to be able to shop online or in stores, get orders delivered when and where they want, and preferably as quickly as possible. This development is called omnichannel and means grocery retailers must transform their logistics networks to meet consumers’ evolving expectations and demands. The omnichannel transformation includes, for

This paper examines the assumption that the volume of domestic patenting in Vietnam is too low and needs to be expanded. The structure and state of development of the Vietnamese economy and a set of relevant systems - including the Science and Technology (S&T) System, the Intellectual Property System, the National Innovation System (NIS), and the Science, Technology and Innovation (STI) Policy

To study cell-free fetal hemoglobin (HbF) and the heme-scavenger α1- microglobulin (A1M) in patients with manifest preeclampsia (PE) and how these proteins performed as possible biomarkers of PE and adverse maternal and fetal outcomes.

AIMS: Although childhood obesity is becoming increasingly prevalent, treatment options are limited and the continued development of effective treatment strategies is necessary. It is equally important to explore involvement of other resources in society, such as sports associations. This study was designed to investigate the possibility of reducing the degree of obesity in obese children by focusi

This master thesis is an attempt to approach the issue of the lack of application of cause advocacy in modern social work practice. The research problem is framed in a way that historical roots of the commitment to social justice in the profession are presented with the further argumentation for the lack of this approach in contemporary social work. A qualitative study has been conducted to fulfil

This thesis looks into the political discourse surrounding the doping scandal that has developed in Russian sport over the last two years. The paper hypothesizes that because of the importance of nationalism and Russia’s great power status, the Putin regime has, despite publicly stating the opposite, actively contributed to the further politicization of sport by returning to a sport discourse clos

The thesis deals with which legal basis seems appropriate to use when the purpose of the data controller is to carry out direct marketing. When processing personal data, the Controller must comply with the principles set out in Article 5 of the GDPR. One of the principles, the Principe of Lawfulness, requires the Processing to be supported on a legal basis in Article 6 of the GDPR. It is stated th

In recent years, Swedish municipalities have introduced programs that combine Swedish language education with vocational training. However, due to the novelty and lack of an established framework, data and research on their effectiveness in improving immigrant labour market performance is limited. This essay addresses this gap by estimating the causal effect of vocational training combined with Sw

In living organisms, respiration is a biological process degrading different carbon substrates, consuming O2, and releasing the carbon as CO2. Plants have several alternative enzymes that are involved in the respiratory processes, as compared to animals. These alternative respiratory enzymes allow electrons to be transferred to oxygen in the mitochondrial inner membrane, but bypassing ATP synthesiIn living organisms, respiration is a biological process degrading different carbon substrates, consuming O2, and releasing the carbon as CO2. Plants have several alternative enzymes that are involved in the respiratory processes, as compared to animals. These alternative respiratory enzymes allow electrons to be transferred to oxygen in the mitochondrial inner membrane, but bypassing ATP synthesi