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Background: Cyclic Cushing's syndrome (cCS) features fluctuating cortisol secretion, often causing diagnostic errors or delays, and possibly poorer outcomes. We aimed to identify unpublished cCS cases to characterise clinical challenges and guide strategies for improving outcomes by characterising cycle patterns, peak frequency, and evaluating complications. Methods: This was a retrospective obser
Background and ObjectivesWhile chronological age is one of the most influential determinants of poststroke outcomes, little is known of the impact of neuroimaging-derived biological "brain age."We hypothesized that radiomics analyses of T2-FLAIR images texture would provide brain age estimates and that advanced brain age of patients with stroke will be associated with cardiovascular risk factors a
Background: Umbilical cord clamping strategies at preterm birth have the potential to affect important health outcomes. The aim of this study was to compare the effectiveness of deferred cord clamping, umbilical cord milking, and immediate cord clamping in reducing neonatal mortality and morbidity at preterm birth. Methods: We conducted a systematic review and individual participant data meta-anal
BACKGROUND: Musculoskeletal disorders include more than 150 different conditions affecting joints, muscles, bones, ligaments, tendons, and the spine. To capture all health loss from death and disability due to musculoskeletal disorders, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) includes a residual musculoskeletal category for conditions other than osteoarthritis, rheuma
In this study, we investigated the regional contributions of carbon dioxide (CO2) at the location of the high Alpine observatory Jungfraujoch (JFJ, Switzerland, 3580ĝ€¯mĝ€¯a.s.l.). To this purpose, we combined receptor-oriented atmospheric transport simulations for CO2 concentration in the period 2009-2017 with stable carbon isotope (δ13C-CO2) information. We applied two Lagrangian particle disper
The various existing measures to quantify upper limb use from wrist-worn inertial measurement units can be grouped into three categories: 1) Thresholded activity counting, 2) Gross movement score and 3) machine learning. However, there is currently no direct comparison of all these measures on a single dataset. While machine learning is a promising approach to detecting upper limb use, there is cu
Dissolved Organic Carbon (DOC) in inland waters plays an essential role in the global carbon cycle and has significant public health effects. Machine learning (ML) together with remote sensing has emerged as a powerful and promising combination to quantify water quality parameters from space. However, inland water sample data for DOC is limited. Hence, little is known about the potential to quanti
Background: The combination of infliximab and immunosuppressant therapy is a standard management strategy for patients with Crohn's disease. Concerns regarding the implications of long-term combination therapy provided the rationale for a formal clinical trial of treatment de-escalation. Our aim was to compare the relapse rate and the time spent in remission over 2 years between patients continuin
The emergence of artificial intelligence, especially machine-learning methods, challenges the set of legal guarantees put in place in Europe to combat discrimination and ensure equal treatment. This paper will focus on cases of algorithmic discrimination in the context of recruitment as a business practice. Particular in the field of recruitment of workers, which has always been a field where EU n
Tidewater glaciers on Svalbard are sensitive indicators of climate change and play a crucial role for Arctic ecosystems. The widespread retreat of tidewater glaciers across Svalbard highlights the need to quantify retreat rates and project when these glaciers will become land-terminating. This study investigates tidewater glacier retreat during historical (1936–1990) and present (2012–2024) period
“Netflix and chill?” It has been 10 years since this phrase has become an innuendo for casual sex. Netflix has become a streaming titan with over 300 million subscribers. The success of Netflix owes much to its original contents emphasising the competitive edge. Netflix categories its soft-core porn titles as Steamy Movies on the platform and even has an established category code for the genre, 11
The construction and real estate sector is a major contributor to global carbon emissions and climate change. Ventilation systems, although essential for maintaining indoor air quality and occupant health, account for a significant share of building operational emissions. In HVAC systems, duct layouts significantly influence ventilation impacts through both the embodied carbon from material produc
Background: Treatment with tumor necrosis factor inhibitors for rheumatoid arthritis has been associated with a decreased risk of cardiovascular disease in observational studies. There are conflicting data on the influence of tumor necrosis factor inhibitors on lipid levels. Objectives: To evaluate the effect of treatment with adalimumab on blood lipid levels, lipoproteins, and atherosclerosis of
Background: Criteria for electrocardiographic detection of acute myocardial ischemia recommended by the Consensus Document of ESC/ACCF/AHA/WHF consist of two parts: The ST elevation myocardial infarction (STEMI) criteria based on ST elevation (ST↑) in 10 pairs of contiguous leads and the other on ST depression (ST↓) in the same 10 contiguous pairs. Our aim was to assess sensitivity (SE) and specif
BackgroundWorldwide, an estimated 5 billion people lack access to safe, affordable surgical care when needed. This leads to millions of avertable deaths and unnecessary morbidity each year. To change this situation, urgent action is needed at many levels, but indicators and data have been lacking to guide improvement.AimsThe aim of this thesis was to describe and evaluate measurement of surgical p
BACKGROUND: Factor VIII (FVIII) and its carrier protein von Willebrand factor (VWF) are associated with risk of arterial and venous thrombosis and with hemorrhagic disorders. We aimed to identify and functionally test novel genetic associations regulating plasma FVIII and VWF. METHODS: We meta-analyzed genome-wide association results from 46 354 individuals of European, African, East Asian, and Hi
Anaerobic processes are an interesting alternative to treat wastewaters instead of aerobic treatments as it allows recovery of energy with the produced biogas while removing organic matter. In the industry, lots of low-strength industrial wastewaters are available and unused for biogas production due to their low concentration of organic material and high volumes (slaughterhouse wastewaters, dairi
Food insecurity is a reality faced by millions of people worldwide. Poor access and availability to food markets, poverty, and uncertain global system futures all exacerbate this issue. In seeking to combat food insecurity for South Carolina residents and improve the viability and resilience of local food markets around Greenville County, South Carolina, this assessment determines optimal potentia
Abstract Author: Therese Hovland and Sofia Stenberg Title: Mötesplats 0413 – An analyze of youths thoughts and opinions about their meeting place [translated title] Supervisor: Anders Östnäs Assessor: Carina Tigerwall Mötesplats 0413 is a culture house for youths at the ages of 16 to 25 years. The purpose of this study was, on the basis of a youth perspective, to critically analyze how the youth
Abstract Authors: Katarina Dahlqvist, Helena Paulsson Title: Best interests of the child – An essay on the child's right to the stepparent Supervisor: Maria Bangura Arvidsson Assessor: Anders Östnäs Our work started in Föräldrabalken 6:9, 1 pcs, which says that if parents have joint custody and should one of them die the custody goes to the other parent. This reason finds its right in the core
