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This study considers the spread, character and development of the Swedish Enlightenment from the early Age of Liberty to the late Karl lohan period. This is done in six case studies three of them biographical and three of them of a more general character partly concerned with the history of concepts; all six case studies touch on the writers' world in the period. Chapter 1, "Dawn", discusses, aft
Bohemia and Moravia, today part of the Czech Republic, was the first territory with a majority of non-German speakers occupied by Hitler’s Third Reich on the eve of the World War II. Tens of thousands of Jewish inhabitants in the so called Protectorate of Bohemia and Moravia soon felt the tragic consequences of Nazi racial politics. Not all Czechs, however, remained passive bystanders during the g
Functional analysis and Monte Carlo simulation were used to quantify uncertainties in model simulation of pollution behaviour and effects. The first-order part of the functional analysis method provides a measure of uncertainties in dependent variables in terms of uncertainties in independent variables. The procedure is based on first-order terms in the Taylor series expansion of the dependent var
BACKGROUND AND AIMS: Although increasing evidence suggests involvement of the distal airway in all stages of asthma, it is not known whether structural changes (defined as airway remodelling) occur in the distal airways of subjects with mild asthma and those with atopy. The aim of this study was to compare control subjects and those with mild asthma in relation to fibroblast phenotypes and remodel
An association between low serum vitamin D levels and poorer melanoma survival has been reported. We have studied inheritance of a polymorphism of the GC gene, rs2282679, coding for the vitamin D-binding protein, which is associated with lower serum levels of vitamin D, in a meta-analysis of 3137 melanoma patients. The aim was to investigate evidence for a causal relationship between vitamin D and
Soil biodiversity plays a key role in regulating the processes that underpin the delivery of ecosystem goods and services in terrestrial ecosystems. Agricultural intensification is known to change the diversity of individual groups of soil biota, but less is known about how intensification affects biodiversity of the soil food web as a whole, and whether or not these effects may be generalized acr
This study examines 24-month post-baseline outcomes for a RCT study of Swedish antisocial youths who received either treatment in multidimensional treatment foster care (MTFC) or treatment as usual (TAU). MTFC, a community-based treatment program, has successfully treated chronic juvenile offenders in the USA This study is the second randomized control study in Sweden that includes MTFC. Compared
Lipophilic statins purportedly exert anti-tumoral effects on breast cancer by decreasing proliferation and increasing apoptosis. HMG-CoA reductase (HMGCR), the rate-limiting enzyme of the mevalonate pathway, is the target of statins. However, data on statin-induced effects on HMGCR activity in cancer are limited. Thus, this pre-operative study investigated statin-induced effects on tumor prolifera
Background: Gene-virus targeted therapy is a promising new method of treating pancreatic cancer. To increase the efficacy and decrease the side-effect, we constructed a conditionally replicative adenovirus (CRAd) expressing human endostatin, with a human Telomoerase Reverse Transcriptase (hTERT) promoter for the regulation of the early stage of adenovirus expression of gene E1a and a Hypoxia Respo
Recently, within a tunneling project, a method for reinjecting discharged groundwater at tunnel level has been investigated. The method was performed by pressurizing a long section of the lining With ungrouted pea gravel as backfill, in a rock mass with low hydraulic conductivity. Water was reinjected through watertight lining into a section where un-grouted pea gravel was used as backfill. The pr
Paja Brava is a native South American grass with a high carbohydrate content. In the current work, the potential of us- ing this feedstock for ethanol production using a simultaneous saccharification and fermentation (SSF) process with the xylose-fermenting yeast Pichia stipitis (Scheffersomyces stipitis) CBS6054 was investigated. The straw material was subjected to SO2 catalyzed steam pretreatmen
In the absence of early B-cell factor 1 (EBF1), B-cell development is arrested at an uncommitted progenitor stage that exhibits increased lineage potentials. Previously, we investigated the roles of EBF1 and its DNA-binding partner Runx1 by evaluating B lymphopoiesis in single (EBF1(het) and Runx1(het)) and compound haploinsufficent (Ebf1(+/-) Runx1(+/-), ERhet) mice. Here, we demonstrate that dec
The aim of this study was to examine the expression of serotonin receptors in patients with breast cancer and to explore their utility as diagnostic and prognostic markers. Immunohistochemical analysis was performed to examine the expression of serotonin (5-HT) receptor subtypes 1A, 1B, 2B and 4 in a tissue microarray containing tumor specimens from 102 patients. Statistical analysis was performed
Purpose: Apolipoprotein M (apoM) retards atherosclerosis development in murine models, and may be regulated by pathways involved in LDL metabolism. Proprotein convertase subtilisin-kexin type 9 (PCSK9) plays a key role in LDL receptor processing. We determined the extent to which plasma apoM is related to PCSK9 levels in subjects with varying degrees of obesity. Methods: We sought correlations bet
In persons with prior paralytic poliomyelitis, progressive muscle weakness can occur after a stable period of at least 15 years. Knowledge is limited about which factors influence changes in lower limb muscle strength in these persons. Objective. To assess changes in lower limb muscle strength annually over 4 years in persons with late effects of polio and to identify prognostic factors for change
Background: Families living with mental illness can experience added burden and eventually own ill health. National and international guidelines support the development of web based solutions to cost-effectively address health care needs. Mapping patterns of internet use may help tailor interventions to effectively address users' needs. Aim: The study's aim was to explore the contents of relatives
Pigs from 154 litters (n = 1132, 19 +/- 3 days of age, 4.9 +/- 1.1 kg of bodyweight) were used in a 3 x 2 factorial design to evaluate two raw materials with nutraceutical properties being used in feeds, spray-dried porcine plasma (SDPP) and a yeast protein meal, and their effects on growth performance, immune parameters and gastrointestinal adaption of piglets to weaning. Factors included dietary
The partial phase diagram of D2O/n-octyl-beta-D-alkyl-glucoside(C(8)G(1))/n-octane has been determined at T = 25 degrees C. The diagram contains a funnel-shaped micellar phase originating from the water corner of the phase diagram D2O/C(8)G(1) with the stern forming a narrow three-phase region, in which the three phases in equilibrium are two microemulsions of similar composition and an excess oil
An assessment of potential methods suitable for degradation and/or reduction of refractory organics was performed on landfill leachate from SYSAV AB, Malmö, Sweden. Pretreatment of the leachate was performed in a sequence batch reactor designed for nitrification in activated sludge. Oxidation of the leachate was then O3, O3/pH adjustment (pH 9 and 10), H2O2, O3/H2O2 and performic acid in lab-scale
Nine species of hyoliths are described based on material collected in Skane, southern Sweden, during the first half of the last century. The material derives from the middle Cambrian (Cambrian provisional Series 3) Exsulans Limestone Bed at Almbacken east of Lund and the Upper Ordovician (Katian-Hirnantian) Lindegard Formation at Tommarp west of Simrishamn. The Almbacken assemblage consists of thr
