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After more than four decades of presence in the manufacturing industry, discrete event simulation has established itself as a powerful technology for a wide range of strategic, tactical, and operational applications in production, logistics, and supply chain management. Discrete event simulation software packages - although not entirely adequate - are relatively capable, and methodologies for perf
Scholars of European fable history over and over again have returned to the question of a possible death of the Aesopic genre. Arguments have been brought forward in accordance with mainly two opposing views. On the one hand, it has been claimed that the fable genre towards the end of the eighteenth century reached a stage of crisis and, more or less, perished. On the other hand, it has been asser
Popular Abstract in Swedish I denna avhandling har morfologin och kristallstrukturen av epitaxiellt växta nanotrådstrukturer undersökts med hjälp av svepelektronmikroskopi (SEM), transmissionselektronmikroskopi (TEM) och multi-slice (MS) simuleringar. Bland annat har vi funnit att de lamellära tvillingar som ofta observeras i III-V nanotrådar växta i <111>B riktningarna tenderar att begränsas av eIn this work, the morphology and crystal structure of epitaxial semiconductor nanowire structures grown by metal-organic vapour phase epitaxy (MOVPE) are studied by electron microscopy methods. In particular, the three-dimensional structure of nanowires and nanotrees has been characterised by scanning electron microscopy (SEM), high-resolution transmission electron microscopy (HRTEM) and multi-sli
A double stranded DNA based fluorescence bioprobe for anticancer agent (doxorubicin) detection is described. This method provides a new way for sensitive DNA/drug interaction study by a homogeneous assay. The probe employs the long-wavelength intercalating fluorophore TOTO-3((R)) (TT3). The anticancer agent, doxorubicin, which interacts with the DNA-TT3 complex, was indirectly measured by the decr
Cubomedusae, or box jellyfish, have the most elaborate visual system of all cnidarians. They have 24 eyes of four morphological types, distributed on four sensory structures called rhopalia. Box jellyfish also display complex, probably visually guided behaviors such as obstacle avoidance and fast directional swimming. Here we describe the strikingly complex and partially bilaterally symmetrical ne
Oral complications are common in patients with haematological malignancies who undergo chemotherapy treatment. A pilot study including 16 haematological patients was carried out to evaluate the oral status using an Oral Assessment Guide (OAG) and to test the reliability of the OAG. The oral assessments were made daily by registered nurses at a Department of Internal Medicine in Sweden. Once a week
A new deglaciation chronology for the ice-free parts of Greenland, the continental shelf and eastern Ellesmere Island (Canada) is proposed. The chronology is based on a new compilation of all published radiocarbon dates from Greenland, and includes crucial new material from southern, northeastern and northwestern Greenland. Although each date provides only a minimum age for the local deglaciation,
The efficacy of a short (Group I) and a prolonged (Group II) course with ciprofloxacin was assessed in patients undergoing transurethral prostatic resection for benign hyperplasia or cancer of the prostate and compared with that of controls without antibiotic (Group III). Both regiments significantly reduced the frequency of postoperative bacteriuria (p less than 0.01) and of severe infectious com
PURPOSE: To determine the effective time window for MR imaging of tumors with blood-brain barrier (BBB) damage after injection of Gd-containing contrast media. MATERIAL AND METHODS: Eleven patients with 15 brain lesions (metastasis, glioma, abscess) were studied with a T1-weighted spin-echo sequence repeated over periods of up to 43 min after contrast injection. A quotient was calculated between t
Nutrient enrichment experiments were carried out in three tropical (once) and three temperate (twice) lakes differing in humic content in order to examine whether there was a relationship between the limiting nutrient for algal growth [nitrogen (N) or phosphorus (P)] and humic content, and whether the prevailing limitation was connected to the relative abundance of autotrophic and phagotrophic phy
In May 2003 Lund University, Sweden, ordered a new AMS facility from National Electrostatics Corp. (NEC), Wisconsin. The system is the first low energy, open air, single stage AMS system (SSAMS). The machine is equipped with a dual ion source sequential injector, which allows measurements of carbon with the masses 12, 13 and 14. The machine operates at 250 kV with the gas stripper, high energy mag
It is unknown whether patients as a consequence of prosthetic joint replacement are at a higher risk of developing cancer. We therefore analyzed cancer incidence following prosthetic knee replacement (TKR). The observed cancer incidence in 14,551 patients from the population-based Swedish Knee Arthroplasty Register who have undergone TKR because of osteoarthrosis (OA, n = 10,120) or rheumatoid art
The Romanian language lectureship in Trondheim was established on June, 5th, 2008. As a novelty the optional course in Romanian language made its debut in January 2009, for “the spring semester” of NTNU. The course is intended for students from all specializations. It is divided into Romanian 1 and Romanian 2, each of them holding 7. 5 credits. The course is concluded with an oral examination and
Identification of agricultural pest insects is an important aspect in insect research and agricultural monitoring. We have performed a methodological study of how spectroscopic techniques and wing-beat frequency analysis might provide relevant information. An optical system based on the combination of close-range remote sensing and reflectance spectroscopy was developed to study the optical charac
This paper describes a measurement of fiducial and differential cross sections of gluon-fusion Higgs boson production in the H → W W∗→ eνμν channel, using 20.3 fb−1 of proton-proton collision data. The data were produced at a centre-of-mass energy of s=8 TeV at the CERN Large Hadron Collider and recorded by the ATLAS detector in 2012. Cross sections are measured from the observed H→ W W∗→ eνμν sig
This qualitative case study aims at understanding when and how industrial designers, working in design consultancies, engage in activities that will influence material selection in the design process. While the extant literature presents material selection processes as a sequence of activities aimed at finding candidate materials, there is paucity of research on material criteria activities. Formu
Adoptive T-cell therapy (ACT) is a highly intensive immunotherapy regime that has yielded remarkable response rates and many durable responses in clinical trials in melanoma; however, 50-60% of the patients have no clinical benefit. Here, we searched for predictive biomarkers to ACT in melanoma. Whole exome-and transcriptome sequencing and neoantigen prediction were applied to pre-treatment sample
The HPV16 E5 open reading frame (ORF) is present on the majority of all alternatively spliced HPV16 mRNAs, but it is currently unknown how well it is translated into E5 protein. To identify HPV16 mRNAs that are efficiently translated into E5, we have generated cDNA plasmids expressing individual, alternatively spliced HPV16 mRNAs with the potential to produce E5. By replacing the E5 ORF with sLuc,
In this article we analyse the actions of Royal Dutch/Shell (since 2021, Shell) considering the campaign against them and their operations in Nigeria in the mid-1990s. Using the concept counter-frames we analyse Shell's internal documentation of the campaign to understand how a multinational extractive industry engaged in disputes of legitimacy and against critiques of their operations. Focusing o
