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The impact of socioeconomic factors on adult and under-five mortality is a subject which has been widely discussed. However, one cannot say the same when it comes to the impact of religion on mortality, and in fact, most of the existing literature has focused on the impact of religious participation on disease-specific mortality among adults. The purpose of this paper was to examine the impact of
BACKGROUND: The role of adenomatous polyposis coli (APC) gene in mitosis might be critical for regulation of genomic stability and chromosome segregation. APC gene mutations have been associated to have a role in colon cancer and since gastric and colon tumors share some common genetic lesions, it is relevant to investigate the role of APC tumor suppressor gene in gastric cancer.METHODS: We invest
Following a macroeconomic stabilization and consistent economic growth during the 2000s, Brazil experienced a continuous decrease on poverty incidence for the first time in its contemporary history. While the literature emphasizes the importance of economic growth alongside social development to fight poverty, the Brazilian experience also displays strong government action through expanding social
Intradialytic hypotension (IDH) is a major drawback of haemodialysis and occurs in more than every fifth dialysis treatment. There is a need for real-time measurement, with an ability to detect IDH before it occurs. Photoplethysmography (PPG) may provide sufficient information about hemodynamic status to prevent IDH. In particular, the venous component may be useful. This thesis aims to investiga
The motivation for the project is to investigate what happens if I add a second Earth in the Solar System and project it forward in time. I add an Earth mass planet (called Earth two) in the same orbit as the Earth on the other side of the Sun (i.e. six months ahead of the original Earth). I then investigate how the perturbation of the second Earth effects the Solar System in the short and the lon
“The important criterion for a graph is not simply how fast we can see a result; rather it is whether through the use of the graph we can see something that would have been harder to see otherwise or that could not have been seen at all.” William S. Cleveland When presenting graphs for people with visual impairments the solutions found on the market today often present pure data values only. Over
In the state of Acre, Brazil, there is ongoing land use change, where inhabitants of this part of the Amazonian rainforest practice shifting agriculture. Practicing this type of agriculture is, according to the SKY Rainforest Rescue organization, damaging to forest ecosystems. This organization aims to educate people in how to maintain sustainable agriculture. By monitoring this shift in agricultu
The purpose of this study was to describe nurses experiences regarding the care they provide to pregnant women suffering from malaria. Tape-recorded qualitative interviews were conducted with a total of eight nurses in clinics and health centers. The method of analysis was inspired by Burnard (1991). The analysis resulted in the following main categories: womens knowledge of Malaria and associated
Background: Global health and sustainable development have increasingly been recognised as important parts of medical education, yet education on these issues remains fragmented and scarce. In 2020, a bill to reform the national medical curricula across all Swedish medical schools was introduced, including a greater emphasis on global health and sustainable development. This study aimed to explore
Pheochromocytomas (PCCs) and paragangliomas (PGLs) are rare neuroendocrine tumors. PGLs can further be divided into sympathetic (sPGLs) and head-and-neck (HN-PGLs). There are virtually no treatment options, and no cure, for metastatic PCCs and PGLs (PPGLs). Here, we composed a tissue microarray (TMA) consisting of 149 PPGLs, reflecting clinical features, presenting as a useful resource. Mutations
Purpose: Extracellular proteins such as aggrecan may be primed with specific glycan-patterns which result in their degradation, and hence may play a role in the pathogenesis of osteoarthritis (OA). To be able to use glycans as molecular biomarkers, the method of analysis of these molecules needs to be validated. The primary aim of this study was to validate quantitative high performance liquid chr
BACKGROUND: Peripheral artery disease is considered to be a manifestation of systemic atherosclerosis with associated adverse cardiovascular and limb events. Data from previous trials have suggested that patients receiving clopidogrel monotherapy had a lower risk of cardiovascular events than those receiving aspirin. We wanted to compare clopidogrel with ticagrelor, a potent antiplatelet agent, in
The standard treatment of glioblastoma, an aggressive brain tumour, includes radiotherapy combined with temozolomide. Based on a randomised trial, showing five months increased survival, TTF has been introduced in the management of patients with good performance status. Data from the Swedish national quality registry for CNS tumours have been analysed for TTF usage. The results demonstrate that 65
En teknik för att förhindra yterosion och samla ytavrinning är bygga jordvallar (1–1,5 m höga) parallellt medhöjdkurvorna. Denna teknik används över stora områden i Tunisien. I denna studie undersöks hur dessa jord-vallar påverkar ytjordens rumsliga variabilitet av markvattenhalt (θ) och salinitet, dels uttryckt som jordenstotala elektriska konduktivitet (σa) och dels som porvattnets elektriska koOne technique for collecting rainwater and prevent soil erosion applied on large areas in Tunisia involves theuse of soil ridges (1–1.5 m high). These contour ridges are constructed parallel to topographical isolines. Theeffects of the contour ridges on the soil water content (θ) distribution, bulk soil salinity σa, and soil water salin-ity (σw) were investigated in the catchment of El-Gouazine in
Background: Increased solar and geomagnetic activity (SGA) may alter sympathetic nervous system activity, reduce antioxidant activity, and modulate physiochemical processes that contribute to atmospheric aerosols, all which may reduce pulmonary function. Objectives: Investigate associations between forced expiratory volume at 1 s (FEV1) and forced vital capacity (FVC) with SGA, and assess whether
Pulmonary arterial hypertension (PAH) is a condition that leads to lethal right heart failure. Available treatments provide relief but are far from curative and the vascular remodeling in PAH has been difficult to decipher. Although pathognomonic to PAH, the plexiform lesions are difficult to define, and there is no consensus regarding their potential hemodynamic impact. Versican is an extracellul
AIMS: Reduced lung function and adverse health outcomes are often observed. This study characterizes genetic susceptibility for reduced lung function and risk of developing a range of adverse health outcomes.METHODS: We studied 27,438 middle-aged adults from the Malmö Diet and Cancer study (MDCS), followed up to 28.8 years. Trait-specific Polygenic scores (PGS) for forced expiratory volume in 1 s
Purpose: To ensure a clinical translation of FLASH radiation therapy (FLASH-RT) for a specific tumor type, studies on tumor control and toxicity within the same biological system are needed. In this study, our objective was to evaluate tumor control and toxicity for hypofractionated FLASH-RT and conventional radiation therapy (CONV-RT) in an immunocompetent rat glioma model. Methods and Materials:
(1) Background: HIV-1 sub-subtype A1 is common in parts of Africa, Russia, former Soviet Union countries, and Eastern Europe. In Pakistan, sub-subtype A1 is the predominant HIV-1 subtype. Preliminary evidence suggests that distinct strains of HIV-1 sub-subtype A1 are circulating in Pakistan; however, an in-depth molecular phylogenetic characterization of HIV-1 sub-subtype A1 strains in Pakistan ha
