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AIMS : Transcatheter aortic valve implantation (TAVI), now a common procedure to treat high-risk patients with severe aortic stenosis, has rapidly been expanding into younger and lower-risk populations, creating a need to better understand long-term outcome after TAVI. The aim of the present investigation was to determine the incidence, risk factors for, clinical presentation of, and outcome after
We have previously shown that exposure of DDT1 MF-2 smooth muscle cells to the agonist bradykinin (BK) resuits in a rapid B2 kinin receptor-mediated internalization of BK followed by degradation of the intracellular BK [Munoz, C. M., and Leeb-Lundberg, L. M. F. (1992) J. Biol. Chem. 267, 303-309]. Here, we show that BK internalization is paralleled by sequestration of the occupied B2 receptors. Se
Artificial groundwater recharge is commonly used for drinking water supply. The resulting water quality is highly dependent on the raw water quality. In many cases, pre-treatment is required. Pre-treatment improves the drinking water quality, although how and to what extent it affects the subsequent pond water quality and infiltration process, is still unknown. We evaluated two treatment systems b
Mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy techniques have been used extensively for metabolite profiling. Although combining these two analytical modalities has the potential of enhancing metabolite coverage, such studies are sparse. In this study we test the hypothesis that combining the metabolic information obtained using liquid chromatography (LC) MS and 1H NMR s
Background: Choice theory stems from psychological concepts like self-concept, successful identity, and quality of the world. The theory encourages adolescents to accept the responsibility for their choices on the one hand and predict the effect of such decisions on their lives on the other hand. The present study aimed to investigate the effectiveness of choice theory-based group training in inte
Biological aerosol particles affect human health, are essential for microbial and gene dispersal, and have been proposed as important agents for atmospheric processes. However, the abundance and size distributions of atmospheric biological particles are largely unknown. In this study we used a laser-induced fluorescence instrument to measure fluorescent biological aerosol particle (FBAP) concentra
BACKGROUND: Segmenting the whole-body somatostatin receptor-expressing tumour volume (SRETVwb) on positron emission tomography/computed tomography (PET/CT) images is highly time-consuming but has shown value as an independent prognostic factor for survival. An automatic method to measure SRETVwb could improve disease status assessment and provide a tool for prognostication. This study aimed to dev
Background: Plaque analysis with coronary computed tomography angiography (CCTA) is a promising tool to identify high risk of future coronary events. The analysis process is time-consuming, and requires highly trained readers. Deep learning models have proved to excel at similar tasks, however, training these models requires large sets of expert-annotated training data. The aims of this study were
Introduction: The Person-Centred Care instrument for outpatient care (PCCoc) is a 36-item patient-reported experience measure with 4 ordered response categories, that aims to capture the degree of perceived person-centred care (PCC) from a patient perspective among persons with long-term conditions. The PCCoc is based on a framework that conceptualises outpatient PCC from lower to higher levels of
Background and aims: Environmental and genetic factors predispose to cardiovascular disease. Some first-generation immigrants have a higher cardiovascular risk in Sweden, while less is known about second-generation immigrants. We aimed to analyze the risk of acute myocardial infarction (AMI) among second-generation immigrants in Sweden. Methods: We included all individuals 18 years of age and olde
Introduction: Understanding violent criminality and its impact on health and eventually the risk of premature mortality is important for efficient future interventions. This study aimed to explore the effect violent criminality had on premature mortality (i.e., death before the age of 65) among individuals with substance use disorders (SUDs). Methods: The cohort was created by identifying all Swed
Background: The perspectives of children with life-threatening or life-limiting (LT/LL) conditions have predominantly been conveyed through their parents rather than heard from the children themselves. Despite an increase in studies focusing on children’s perspectives in pediatric palliative care, this research remains limited, particularly in including children who are unable to express themselve
Groundwater drought, as a form of hydrological drought, embodies the distinctive characteristics of the aquifer and human-induced disruptions within the hydrological system. The intricate nature of groundwater flow systems, coupled with challenges in acquiring field observations related to aquifers, poses significant challenges in quantitatively characterizing groundwater drought. The present pape
Objectives To study informed consent to midwifery practices and interventions during the second stage of labor and to investigate the association between informed consent and experiences of these practices and interventions and women's experiences of the second stage of labor. Methods This study uses an observational design with data from a follow-up questionnaire sent to women one month after giv
Job satisfaction is a complex concept that has mainly been investigated in a quantitative nature from several perspectives. Most past studies have focused solely on investigating full-time employees quantitatively, without taking into account other employment types such as part-time student employees, or other methods of data collection. Additionally, a lack of studies exist focusing on comparing
Aquaculture is an expanding industry, supplying closer to 50% of the total fish consumption. Commercialized fish production faces sustainability challenges which are important to address. Aquaponics uses wastewater from aquaculture to grow plants using hydroponics. This is a step towards making the industry more sustainable, but the practice is not straightforward. The plants and the fish thrive a
Introduction: Wood packaging consumes over twenty percent of industrial timber harvests in the United States. Organised reuse of wood packaging can reduce timber consumption but is not widely practised. Existing research on circular wood packaging systems is limited in scope, focusing on individual design and process interventions at the firm level. This thesis constitutes a novel investigation o
Ny avfallslagstiftning tvingar kommunerna att se över sina avfallsabonnemang I dagsläget bestämmer varje kommun själv hur många källsorterade avfallsfraktioner de vill hämta upp hos hushållen samt huruvida matavfall ska sorteras ut separat eller slängas blandat med restavfall. Ny avfallslagstiftning från EU och regeringen tvingar kommunerna att se över sina avfallsabonnemang så att de lever upp tRecycling reduces the need for new raw materials and greenhouse gas emissions. In addition, the new waste legislation from the EU and the Swedish government imposes higher recycling requirements on Swedish municipalities. Starting from January 1, 2024, it will be mandatory for all EU member states to separately collect food waste through curbside collection. The Swedish government has also decided
Palsa mires are typical wetland landscapes of the Arctic regions, consisting of mosaics of palsas (raised formations of peat and permafrost) and shallow ponds, all embedded in wet mires. These heterogeneous habitats support rich and abundant wader populations, which breed there during the short Arctic summer. Although being threatened by climate change, relatively little is known about the ecologi
Particle size can be an important variable to know in many different areas, be it smoke simulations, toxicity of materials or tests of face masks. Fires in a reduced oxygen environment can occur for ventilation-controlled fires or in areas with artificially lowered oxygen levels. The effects of lower concentrations of oxygen on heat release rate, smoke production etc. has been studied, but any eff
