Sökresultat

Popular Abstract in Swedish Systemisk lupus erythematosus (SLE) är en autoimmun reumatisk systemsjukdom som drabbar flera av kroppens olika organsystem, såsom rörelseapparat, hud och inre organ. Vidare ses en mångfald störningar i kroppens immunsystem. Sjukdomen drabbar oftast kvinnor. Vad som orsakar SLE är ännu så länge ofullständigt klarlagt, men man vet att yttre faktorer (miljöfaktorer) samveSystemic lupus erythematosus (SLE) is a complex autoimmune disease in which environmental factors interact with genetic factors in the development of the disease process and evolution of clinical manifestations. In this thesis both exogenous factors and host factors were investigated, as well as important immunopathological aspects including involvement of immune complex (IC), the complement syste

Popular Abstract in Swedish Inom växtriket finns det ca 3000 arter som är parasitiska och dessa växer i nästan alla större ekosystem på land. Parasitiska växter kan delas in på olika sätt, helparasiter respektive halvparasiter. Denna indelning baserar sig på om de saknar klorofyll och tar all sin näring från sin värdväxt (helparasiter) eller har klorofyll och kan själva framställa kolhydrater men Parasitic plants are found in nearly every major terrestrial ecosystem and can be divided into two groups, holoparasites (lacking chlorophyll) and hemiparasites (chlorophyllous). The host-parasite connection is either situated above (stem parasites) or below ground (root parasites). In this thesis I examine the host-parasite interactions, host range and selection, and population dynamics of four r

Popular Abstract in Swedish Ett högt fiberintag från grönsaker, frukt och sädesslag som havre och korn minskar risken för hjärt- och kärlsjukdomar och typ 2 diabetes. Havre och korn har en hög halt av lösliga kostfiber, så kallade beta-glukaner (beta-glukaner) och studier har visat att beta-glukaner har intressanta hälsoeffekter. Ett dagligt intag av beta-glukaner från havre eller korn kan sänka kSince soluble fibre in the form of the cereal beta-glucans found in oats and barley has been shown to have a positive effect on lipid and glucose metabolism, people at risk of developing cardiovascular diseases or diabetes might benefit from that a variety of palatable food products containing beta-glucans being available to them. The aim of the papers presented in the thesis was to evaluate the m

A comprehensive study of the molecular active landscape of human cells can be undertaken to integrate two different but complementary perspectives: transcriptomics, and proteomics. After the genome era, proteomics has emerged as a powerful tool to simultaneously identify and characterize the compendium of thousands of different proteins active in a cell. Thus, the Chromosome-centric Human Proteome

Crystalline lenses with multiple focal lengths in monochromatic light (multifocal lenses) are present in many vertebrate groups. These lenses compensate for chromatic aberration and create well-focused color images. Stabilization of the lens within the eye and the ability to adjust focus are further requirements for vision in high detail. We investigated the occurrence of multifocal lenses by phot

According to the classical perspective, polity size and democracy are inversely related. In this article, we argue that there is an important exception that manifests itself at the district level in settings where multiparty competition is allowed. Specifically, we find that larger districts encourage greater contestation. This results from a little-noticed mechanical effect as well as from severa

Recent reports on adult fracture epidemiology have focused mainly on the hip in elderly where increasing rates lately have changed to a decline. New reports of the preponderance of non-hip fractures in expenditure call for a wider scope. We therefore examined current overall and site-specific fracture epidemiology in adults. We ascertained all fractures diagnosed in in- and out-patient care in all

Aim The northern limits of temperate broadleaved species in Fennoscanndia are controlled by their requirements for summer warmth for successful regeneration and growth as well as by the detrimental effects of winter cold on plant tissue. However, occurrences of meteorological conditions with detrimental effects on individual species are rare events rather than a reflection of average conditions. W

A detailed three-dimensional regional chemical transport model (Particulate Matter Comprehensive Air Quality Model with Extensions, PMCAMx) was applied over Europe, focusing on the formation and chemical transformation of organic matter. Three periods representative of different seasons were simulated, corresponding to intensive field campaigns. An extensive set of AMS measurements was used to eva

Many Helicobacter spp. were isolated from the stomach, intestinal tract, and liver of different animals and humans. The association between Helicobacter spp. and hepatobiliary diseases, including hepatocellular carcinoma, was thoroughly examined, indicating a potential role of the bacteria in the progression toward cancer. In our work, we screened 97 liver biopsies from patients with chronic liver

Biomass can be converted into liquid and gaseous biofuels with good efficiency. In this study, the conversion of industrial hemp (Cannabis sativa L.), a biomass source that can be cultivated with a high biomass yield per hectare, was used. Steam pretreatment of dry and ensiled hemp was investigated prior to ethanol production. The pretreatment efficiency was evaluated in terms of sugar recovery an

The intensification of the hydrological cycle, with an observed and modeled increase in drought incidence and severity, underscores the need to quantify drought effects on carbon cycling and the terrestrial sink. FLUXNET, a global network of eddy covariance towers, provides dense data streams of meteorological data, and through flux partitioning and gap filling algorithms, estimates of net ecosyst

An investigation was made of the effects on endogenous antioxidant enzyme activities and H2O2-induced lipid peroxidation inhibition in human red blood cells of the crude MeOH extract and its EtOAc, n-BuOH, and H2O sub-extracts obtained from aerial parts of Geranium psilostemon Ledeb., as well as compounds isolated from the most active EtOAc extract. Gallic acid (1), methyl gallate (2), pusilagin (

Nager A, Szulkin R, Johansson S-E, Johansson L-M, Sundquist K. High lifelong relapse rate of psychiatric disorders among women with postpartum psychosis. Nord J Psychiatry 2013;67:53-58. Background: The relapse rate for psychiatric disorders after postpartum psychosis is high. Apart from subsequent puerperal periods, previous studies have not examined when relapses in psychiatric disorders occur.

Measurements of the variation of inclusive jet suppression as a function of relative azimuthal angle, Delta phi, with respect to the elliptic event plane provide insight into the path-length dependence of jet quenching. ATLAS has measured the Delta phi dependence of jet yields in 0.14 nb(-1) of root s(NN) = 2.76 TeV Pb + Pb collisions at the LHC for jet transverse momenta p(T) > 45 GeV in differen

As part of multidisciplinary surveys of three Behavioural Phenotype Conditions (BPCs); Möbius sequence (Möbius), CHARGE syndrome (CHARGE) and oculo-auriculo-vertebral spectrum (OAV), autism spectrum conditions (ASCs) was diagnosed in 45%, 68% and 42% of the individuals, respectively. Diagnostic difficulties due to additional dysfunctions such as mental retardation (MR), impaired vision, reduced he

Adsorption of uncharged homopolymers of various flexibilities in good solvent onto planar surfaces Lit various polymer-surface interaction strengths have been investigated by employing a coarse-grained bead-spring polymer model using simulation techniques. The polymer flexibility ranged from fully flexible to rod-like polymers, and the adsorption strength varied from weak to strong adsorption. Equ

QuestionHow do pollen-based functional and phylogenetic diversity help to explain post-glacial vegetation change in relation to climate and human influence? LocationEstonia and Latvia, NE Europe. MethodsWe used a data set of 1062 pollen samples from 20 sites covering the last 14500yrs to estimate plant richness, evenness, functional and phylogenetic diversity (community-weighted mean and mean pair

Speech is usually assumed to start with a clearly defined preverbal message, which provides a benchmark for self-monitoring and a robust sense of agency for one's utterances. However, an alternative hypothesis states that speakers often have no detailed preview of what they are about to say, and that they instead use auditory feedback to infer the meaning of their words. In the experiment reported

OBJECTIVEExamine the efficacy and safety of lixisenatide (20 μg once daily, administered before the morning or evening meal) as add-on therapy in type 2 diabetes patients insufficiently controlled with metformin alone.RESEARCH DESIGN AND METHODSA 24-week, randomized, double-blind, placebo-controlled study in 680 patients with inadequately controlled type 2 diabetes (HbA1c 7-10% [53-86 mmol/mol]).