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Effect of two novel CGRP-binding compounds in a closed cranial window rat model

We investigated the in vivo effects of two novel calcitonin gene-related peptide (CGRP) binding molecules in the genuine closed cranial window model in the rat. The RNA-Spiegelmer (NOX-C89) and the monoclonal CGRP antibody are CGRP scavengers and might be used as an alternative to CGRP-receptor antagonists in the treatment of migraine. Rats were anaesthetized and a closed cranial window establishe

p53-dependent and -independent differentiation of leukemic U-937 cells : relationship to cell cycle control

Observations based on overexpression of the suppressor gene p53 or interference with endogenous p53 support a role for p53 in mediating not only growth inhibition and apoptosis but also differentiation. The aim of this study was to characterize the mechanisms of p53-dependent differentiation in the monoblastic leukemia cell line U-937. These cells were transfected with a mutant of the p53 gene exp

Free fatty acid receptor 1 (FFA(1)R/GPR40) and its involvement in fatty-acid-stimulated insulin secretion.

Free fatty acids (FFA) have generally been proposed to regulate pancreatic insulin release by an intracellular mechanism involving inhibition of CPT-1. The recently de-orphanized G-protein coupled receptor, FFA(1)R/GPR40, has been shown to be essential for fatty-acid-stimulated insulin release in MIN6 mouse insulinoma cells. The CPT-1 inhibitor, 2-bromo palmitate (2BrP), was investigated for its a

Summary of the recommendations on sexual dysfunctions in men

Introduction. There are few published guidelines for the management of sexual dysfunctions in men and women, despite the prevalence and lack of attention to these problems. Disorders of sexual function in men include erectile dysfunction, orgasm/ejaculation disorders, priapism, and Peyronie's disease. Aim. To provide evidence-based and expert-opinion consensus guidelines for the clinical managemen

Use of benzodiazepines and benzodiazepine receptor agonists during pregnancy: neonatal outcome and congenital malformations

Background Exposure to Benzodiazepines (BZD) during foetal life has been suggested to contribute to neonatal morbidity and some congenital malformations, for example, orofacial clefts. Here we aimed to study the neonatal outcome and congenital malformations in neonates whose mothers reported use of BZD and/or hypnotic benzodiazepine receptor agonists (HBRA) during pregnancy. Methods In the Swedish

Association of height, BMI, and smoking status with prostate cancer risk before and after the introduction of PSA testing in Sweden

Prostate cancer (PCa) incidence has steadily increased in Sweden, more steeply in the mid-1990s caused by increased opportunistic prostate-specific antigen (PSA) testing. Tallness, normal weight, and non-smoking are associated with more PSA testing, which increases detection of low-risk and localised PCa. We investigated time trends of height, body mass index (BMI), and smoking with PCa risk in 17

Tensions influencing the risk management of hexavalent chromium exposure at Swedish workplaces : evidence from the SafeChrom project

In this study we investigate risk management trade-offs by evaluating how key persons at workplaces with a potential for exposure to hexavalent chromium (Cr(VI)) reason about what is practically possible in terms of exposure reduction. While the included companies (N = 14) represented different types of processes and work-tasks, interviewees all identified that many types of hazards compete for at

Prevention of Metabolic Impairment by Dietary Nitrate in Overweight Male Mice Improves Stroke Outcome

Background/objectives: Being overweight increases the predisposition to obesity and type 2 diabetes (T2D), which significantly elevate stroke risk and the likelihood of severe post-stroke disability. Dietary nitrate (NO3−) supplementation can mitigate obesity and metabolic impairments, making it a promising approach to halt overweight people from developing overt obesity/T2D, thereby potentially a

GP turnover in a multiprofessional team-based primary care system : evidence from Sweden

BACKGROUND: GP recruitment and retention difficulties challenge the traditional general practice model. Task-shifting and relieving GPs from financial risk have been suggested to make primary care more attractive. In Sweden's multiprofessional team-based primary care system, GPs usually work as salaried employees and there is extensive task-shifting. Salaried employment facilitates mobility, poten

The best fixation target revisited : New insights from retinal eye tracking

In many tasks, participants are instructed to fixate a target. While maintaining fixation, the eyes nonetheless make small fixational eye movements, such as microsaccades and drift. Previous work has examined the effect of fixation point design on fixation stability and the amount and spatial extent of fixational eye movements. However, much of this work used video-based eye trackers, which have i

Generalizable gesture classification of HDsEMG using volume representations of muscles averaged across multiple individuals

Human hands can perform far more gestures than the number of muscles controlling them, as most gestures result from coordinated combinations of muscle activations and relaxations. This complexity poses a key challenge for human-machine interfaces performing gesture classification based on electromyography (EMG). Rather than identifying all conceivable gestures, it may be simpler to instead identif

Allern_etal

Allern_etal The 2nd EuroSoTL conference, June 8-9 2017, Lund, Sweden Peer observation of Teaching as motivation for educational development – From teaching as private enterprise to a collective approach M. Allern1, M. A. Sundset2, and R. Sandvoll1, 1RESULT (Center for teaching, learning and technology), UiT The Arctic University of Tromsø, 9037 Tromsø, Norway, 2Department of Arctic and Marine Biol

https://konferens.ht.lu.se/fileadmin/_migrated/content_uploads/Allern_etal.pdf - 2026-05-07

Microsoft Word - Skutnabb_Kangas_abstract_21Feb.docx

Microsoft Word - Skutnabb_Kangas_abstract_21Feb.docx Linguistic Human Rights (LHRs) do they exist?/ Språkliga mänskliga rättigheter – finns de? Fil.dr. Tove Skutnabb-Kangas, 21 februari 2020. www.Tove-Skutnabb-Kangas.org Nu har Sverige börjat be om ursäkt för det som Sverige har gjort åt samerna. Vad med invandrarna? Och gör man i dag om samma misstag med asylsökare och deras barn? All allvarlig i

https://konferens.ht.lu.se/fileadmin/user_upload/sol/aemnen/sektion3/Skutnabb_Kangas_abstract_21Feb.pdf - 2026-05-07

No title

Generative Linguistics in the Old World 36 Lund University · April 3–5, 2013 Verb Clusters and the Semantics of HeadMovement Rajesh Bhatt & Stefan Keine University of Massachusetts, Amherst {bhatt, keine}@linguist.umass.edu • Main Claims: 1. Head movement can have semantic eects. It can hence not be a PF operation (pace Chomsky 2001). 2. To obtain the desired semantic eects of head movement, the d

https://konferens.ht.lu.se/fileadmin/user_upload/sol/ovrigt/konferens_glow36/Handouts_and_Presentations/Bhatt_and_Keine.pdf - 2026-05-07

stenalt_lassesen_ver2

stenalt_lassesen_ver2 The 2nd EuroSoTL conference, June 8-9 2017, Lund, Sweden An exploratory study of undergraduate law students’ experience of online peer and self-grading: Towards an experiential perspective M. H. Stenalt and B. Lassesen, Center for Teaching and Learning, Aarhus University, Denmark ABSTRACT: Many studies have reported on the use of online technology in teaching and learning to

https://konferens.ht.lu.se/fileadmin/_migrated/content_uploads/Stenalt_Lassesen.pdf - 2026-05-07

Title page

Title page WPSS WORKING PAPERS IN SCANDINAVIAN SYNTAX June 2016 Issue 96 Special issue on Icelandic Working Papers in Scandinavian Syntax is an electronic publication for current articles relating to the study of Scandinavian syntax. The articles appearing herein are previously unpublished reports of ongoing research activities and may subsequently appear, revised or unrevised, in other publicatio

https://projekt.ht.lu.se/fileadmin/_migrated/content_uploads/WPSS_17.pdf - 2026-05-09

Climate Change Adaptation - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law

Climate Change Adaptation - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Programme Work

https://rwi.lu.se/climate-change-adaptation-building-resilience/ - 2026-05-09

Insikt och Handling 1

Insikt och Handling 1 INSIKT OCH HANDLING Utgiven av Hans Larsson Samfundet Volym 1 REDAKTÖR: ROLF EKMAN DISTRIBUTION: AB PH. LINDSTEDTS UNIV.-BOKHANDEL TRYCKNING: SKÅNSKA CENTRALTRYCKERIET, LUND 1955 ISSN: 0436-8096 PDF: TABULA, MÄRSTA 2020 ISBN: 978-91-88702-11-1 VERSION 1.0 — 2020-05-14 – 2 – Innehåll 4 Hans Larsson, Ernst Cassirer och Axel Hägerström Alf Ahlberg 17 Om tolkningen av filosofiska

https://www.fil.lu.se/fileadmin/user_upload/fil/dokument/hanslarsson/Insikt_och_handling_vol_1.pdf - 2026-05-09

Flexible Networks are Sustainable Networks

Flexible Networks are Sustainable Networks | Department of Automatic Control Faculty of Engineering, LTH Search Department of Automatic Control LTH, Faculty of Engineering Education Research External Engagement Personnel Publications About, Contact Home  >  Research  >  Large-Scale Systems and Learning  >  Flexible Networks are Sustainable Networks Denna sida på svenska This page in English Flexib

https://www.control.lth.se/research/large-scale-systems-and-learning/flexible-networks-are-sustainable-networks/ - 2026-05-09

No Slide Title

No Slide Title Is child L2 French like 2L1 or like adult L2? Suzanne Schlyter & Jonas Granfeldt Lund University IASCLXI, Edinburgh, 28th July to 1st August Questions If there is a qualitative difference between (2)L1 and adL2 acquisition, at what age is the cut-off point? (5, 4, 3 … years?) To what extent do early successive bilinguals differ from 2L1 children and adult and older child L2 learners

https://projekt.ht.lu.se/fileadmin/user_upload/sol/ovrigt/projekt_sprakutv_franska/Edinburgh_08_Schlyter.ppt - 2026-05-09