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Syftet med denna undersökning var att bestämma en 1 kg isvästs kylverkan på kroppen vid brandmansarbete. Testerna genomfördes i en klimatkammare, i en container med extrem strålningsvärme och i ett rökdykningshus med värme och tungt arbete. Den faktiska kylverkan mättes också med en termisk docka. Fyra erfarna brandmän deltog i försöken. I alla tester bar försökspersonerna standardklädsel för branThe aim of the present study was to examine the effects of wearing a light-weight ice-vest (1kg, water) on physiological and subjective responses in fire fighter’s work. The experiments were carried out in a climatic chamber, in a container under extreme radiant heat, and during simulated smoke-diving. In addition, the physical cooling effect of the ice-vest was measured with a thermal mannequin.

Popular Abstract in Swedish Syftet med denna avhandling är att studera den vanligaste behandlingskomplikationen vid blödarsjuka, antikroppsbildning, samt att studera sambandet mellan genen som orsakar sjukdom och det protein som denna gen kodar för. Det övergripande syftet är att forskningsresultaten ska kunna användas för att förbättra vården för familjer med blödarsjuka (hemofili). Resultaten vThe general objective of the research underlying this dissertation was to conduct clinical and basic scientific studies to further elucidate the hemophilia and the coagulation process, with the goal of improving the care of families with these disorders. More specific aims were to evaluate epidemiological, genetic, clinical, and biochemical aspects of the development of inhibitors (antibodies) aga

Syftet med denna undersökning var att bestämma en 1 kg isvästs kylverkan på kroppen vid brandmansarbete. Testerna genomfördes i en klimatkammare, i en container med extrem strålningsvärme och i ett rökdykningshus med värme och tungt arbete. Den faktiska kylverkan mättes också med en termisk docka. Fyra erfarna brandmän deltog i försöken. I alla tester bar försökspersonerna standardklädsel för branThe aim of the present study was to examine the effects of wearing a light-weight ice-vest (1kg, water) on physiological and subjective responses in fire fighter’s work. The experiments were carried out in a climatic chamber, in a container under extreme radiant heat, and during simulated smoke-diving. In addition, the physical cooling effect of the ice-vest was measured with a thermal mannequin.

There has been an increased focus in society on preparedness for emergency response in recent years. Today there is legislation that requires all Swedish authorities at the local, regional and national levels to prepare for emergency management and response. Since the task is rather new, most authorities are just beginning to address it. How the preparedness process should be designed and integrat

Mid-infrared polarization spectroscopy (IRPS) was applied to detect HCl in flames. For the first time, sensitive and nonin trusive HCl detection with a manner of high spatial- and temporal-resolution in harsh reactive gas flow has been demonstrated in this work. In an atmospheric pressure premixed CH4/O-2/Ar flat flame, trace level HCl was prepared by seeding small amount chloroform through the Ar

Popular Abstract in Swedish Cancer i tjock- och ändtarmen är idag den tredje vanligaste formen av till döden ledande cancer i världen. Den är vanligast i de högindustrialise-rade delarna av världen: Europa, Nord-Amerika och Australien. Prognosen för den enskilde patienten är helt beroende på cancerns utbredning vid diagnostillfället. Cancerns utbredning bedöms idag enligt olika indelningsprincipeAim of the study Today´s methods for the staging of rectal carcinoma: ultrasonography with transrectal probe, CT, MRI or MRI with a rectal coil, all have limitations. The aim was therefore to develop a new, double-contrast MRI method for evaluation of rectal carcinoma. The idea was that a rectally applied contrast medium causing distension and signal void of the rectal lumen and an intravenous inj

Today we use products to shape our identity, by communicating to others who we are and what we want to be. Using products for communication of identity seems especially important for young adults. Persons with disabilities live with double identities. Sometimes it is important to be a person with a disability (e.g., someone in contact with health care and other welfare systems in society), while a

Fission track analysis (FTA) was developed to be applied to ultra-low levels of 239Pu in bioassay samples. An analytical protocol was established for the FTA processing. The detection limit was determined to 1.5 µBq and the calibration constant was 24 fission fragments per µBq 239Pu. Naturally occuring nuclides of thorium and uranium, present in biological and environmental samples, did not interf

Failure to express the Gimap5 protein is associated with lymphopenia (lyp) and linked to spontaneous diabetes in the diabetes-prone BioBreeding (BBDP) rat. Gimap5 is a member of seven related genes located within 150 Kb on rat chromosome 4. Congenic DR.lyp/lyp rats, where BBDP lyp was introgressed onto the diabetes-resistant BBDR background (BBDR.BBDP.lyp/lyp), all develop diabetes between 46 and

Pre-fractionation of a complex mixture of proteins increases the resolution in analytical separations of proteins from cells, tissues or organisms. Here we demonstrate a novel method for pre-fractionation of membrane proteins by a detergent-based aqueous two-phase system. Membrane proteins are strongly under-represented in proteomic studies based on two-dimensional electrophoresis (2-DE). As a mod

The etiology of exercise-induced rib stress fractures (RSFs) in elite rowers is unclear. The purpose of the study was to investigate thoracic muscle activity, movement patterns and muscle strength in elite rowers. Electromyographic (EMG) and 2-D video analysis were performed during ergometer rowing, and isokinetic muscle strength was measured in seven national team rowers with a history of RSF and

OBJECTIVE: To compare the frequency of rebleeding and endometrial growth during a 12-month follow-up period between women with postmenopausal bleeding and an endometrial thickness < 5 mm managed by dilatation and curettage, and those managed by ultrasound follow-up. DESIGN: Consecutive women with postmenopausal bleeding and an endometrial thickness < 5 mm were randomized to ultrasound follow-up af

Background Open abdomen (OA) treatment often results in difficulties in closing the abdomen. Highest closure rates are seen with the vacuum-assisted wound closure (VAWC) technique. However, we have experienced occasional failures with this technique in cases with severe visceral swelling needing longer treatment periods with open abdomen. Feasibility and short-term outcome of a novel combination o

Aims: To describe environmental and personal tick-preventive measures and their predictors, taken by a population living in a highly tick-endemic area. Methods: Owing to the recent confirmation of human tick-borne encephalitis cases, vaccination against tick-borne encephalitis was offered to the population living in the endemic area through the use of leaflets and media campaigns. At the time of t

Background: In the Malmö Diet and Cancer study, information on dietary habits was obtained through a modified diet history method, combining a 7-day menu book for cooked meals and a diet questionnaire for foods with low day-to-day variation. Half way through the baseline data collection, a change of interview routines was implemented in order to reduce interview time. Methods: Changes concentrated

Many heavy metals inhibit electron transfer reactions in Photosystem II (PSII). Cd2+ is known to exchange, with high affinity in a slow reaction, for the Ca2+ cofactor in the Ca/Mn cluster that constitutes the oxygen-evolving center. This results in inhibition of photosynthetic oxygen evolution. There are also indications that Cd2+ binds to other sites in PSII, potentially to proton channels in an

Background. In a search for immunosuppressive drugs having novel mechanisms, monocarboxylate transporter (MCT-1) inhibitors were identified that markedly inhibited immune responses. Here, we report the effects of AR-C117977, a potent MCT-1 inhibitor, on alloimmune responses in the rat. Methods. In vitro activity was determined in a rat mixed lymphocyte response (MLR). In vivo activity was tested i

BACKGROUND: Degranulation of eosinophils in target tissues is considered a key pathogenic event in major chronic eosinophilic diseases. However, because of a lack of appropriate methods, little is known about degranulation of eosinophils in common eosinophilic diseases. METHODS: Using transmission electron microscopic (TEM) analysis, a novel approach has been devised and validated to quantify eosi

We examined the influence of widely varied consumption of fatty fish from the Baltic Sea and of age on plasma concentrations of polychlorinated biphenyls (PCBs), polychlorobiphenylols (OH-PCBs), 2, 2-bis(4-chlorophenyl)-1,1,1-trichloroethane (4,4'-DDT), 2, 2-bis(4-chlorophenyl)-1,1-dichloroethane (4,4'-DDE), 2,2',4, 4'-tetrabromodiphenyl ether (BDE-47), hexachlorobenzene (HCB), and pentachlorophen

Laser Doppler flowmetry (LDF) was used to study skin blood flow in the finger tip and on the dorsum of the hand in healthy volunteers. Vasodilatation in the finger tip was induced by immersing the arm in water at 42 degrees C, and vasodilatation in the dorsum of the hand by intracutaneous injection of dihydralazine. Simultaneous measurements were performed using venous occlusion plethysmography (f