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Prevalence of severe and moderate anthropometric failure among children in India, 1993-2021

Though child anthropometric failure (CAF) is a persistent problem in India, previous studies have often neglected state-level variance and aggregated moderate and severe CAF categories. This study addresses this gap by examining moderate and severe malnutrition across India's states and union territories (UTs) from 1993 to 2021. Data of children under 2 years old from five waves of National Family

"Younger" and "Older" Old Adults Who Die by Suicide : A Comparison Study and Cluster Analysis

OBJECTIVES: To compare sociodemographic, clinical, and suicide-specific characteristics between younger old (aged 65-74) and older old (aged 75+) adults who died by suicide in 2015, and to identify clinically relevant subgroups in the entire study cohort 65+ through cluster analysis.DESIGN: Retrospective cohort study.SETTING: All health care units across Sweden.PARTICIPANTS: Individuals aged 65+ w

Chronic Airflow Limitation, Lower Respiratory Symptoms, COPD and Chronic Rhinosinusitis in a Middle-Aged Population : The Swedish CArdioPulmonary bioImage Study (SCAPIS). A Link Between the Lower and Upper Airways

Purpose: Chronic rhinosinusitis (CRS) is related to asthma and chronic obstructive pulmonary disease (COPD). However, combined data on CRS, pulmonary function, lower airway symptoms, and cigarette smoking from the general population are lacking. The current study investigates the relationships between CRS and chronic airflow limitation (CAL), lower airway symptoms and COPD in a middle-aged populat

Efficacy and safety of varenicline and bupropion, in combination and alone, for alcohol use disorder : a randomized, double-blind, placebo-controlled multicentre trial

Background: Alcohol use disorder (AUD) is associated with an enormous burden of disease and cost to society. The dopamine deficiency hypothesis posits that negative reinforcement generated by a low brain dopamine state drives ethanol intake. Here, we evaluated the efficacy and safety of combined administration of two dopamine-enhancing drugs, varenicline (a partial nicotinic acetylcholine receptor

Guanidinium can both cause and prevent the hydrophobic collapse of biomacromolecules

A combination of Fourier transform infrared and phase transition measurements as well as molecular computer simulations, and thermodynamic modeling were performed to probe the mechanisms by which guanidinium (Gnd+) salts influence the stability of the collapsed versus uncollapsed state of an elastin-like polypeptide (ELP), an uncharged thermoresponsive polymer. We found that the cation's action wa

A feasibility and safety trial investigating a device for swift and standardized median laparotomy closure

Purpose: Abdominal wall complications can be reduced by adhering to guidelines for midline laparotomy closure. However, implementation of guidelines can be challenging. To address this issue, a laparotomy closure device for swift and standardized abdominal closure was developed. The study evaluated the quality of the suture, safety, and speed of the device in a clinical setting. Methods: A prospec

Accuracy of automated intracerebral hemorrhage volume measurement on non-contrast computed tomography : a Swedish Stroke Register cohort study

Purpose: Hematoma volume is the strongest predictor of patient outcome after intracerebral hemorrhage (ICH). The aim of this study was to validate novel fully automated software for quantification of ICH volume on non-contrast computed tomography (CT). Methods: The population was defined from the Swedish Stroke Register (RS) and included all patients with an ICH diagnosis during 2016–2019 in Regio

Photophysical Integrity of the Iron(III) Scorpionate Framework in Iron(III)-NHC Complexes with Long-Lived 2LMCT Excited States

Fe(III) complexes with N-heterocyclic carbene (NHC) ligands belong to the rare examples of Earth-abundant transition metal complexes with long-lived luminescent charge-transfer excited states that enable applications as photosensitizers for charge separation reactions. We report three new hexa-NHC complexes of this class: [Fe(brphtmeimb)2]PF6(brphtmeimb = [(4-bromophenyl)tris(3-methylimidazol-2-yl

Stories of paediatric palliative care : a qualitative study exploring health care professionals’ understanding of the concept

Background: By sharing patient stories, health care professionals (HCPs) may communicate their attitudes, values and beliefs about caring and treatment. Previous qualitative research has shown that HCPs usually associate paediatric palliative care (PPC) with death or dying and that they find the concept challenging to understand and difficult to implement. Attending to HCPs’ stories may provide a

Risk of recurrence after endoscopic resection of nonpedunculated T1 colorectal cancer

BACKGROUND: The long-term outcome after local excision of T1 colorectal cancer (CRC) remains unknown. The aim of this study was to examine clinical and histopathological risk factors for recurrence in patients with T1 CRC undergoing endoscopic resection.METHODS: This was a retrospective registry-based population study on prospectively collected data of all patients with nonpedunculated T1 CRC unde

One-year incidence of sexual harassment and the contribution to poor mental health in the adult general population

Background: Sexual harassment (SH) has been highlighted as an important determinant for mental health. The aims of this study were to describe SH in terms of cumulative 1-year incidence, exposed groups, types of perpetrators and settings, and to measure the association between SH and poor mental well-being. Methods: Data from two waves of the Scania Public Health Cohort Study, comprising 7759 rand

Longitudinal analysis of ANA in the Systemic Lupus International Collaborating Clinics (SLICC) Inception Cohort

Objectives A perception derived from cross-sectional studies of small systemic lupus erythematosus (SLE) cohorts is that there is a marked discrepancy between antinuclear antibody (ANA) assays, which impacts on clinicians' approach to diagnosis and follow-up. We compared three ANA assays in a longitudinal analysis of a large international incident SLE cohort retested regularly and followed for 5 y

Aerosol formation and emissions from realistic compartment fires

Firefighters are occupationally exposed to a large number of toxic compounds (IARC 2010). The occupational exposure of firefighters has been classified as potentially carcinogenic (class 2B, IARC; (Straif K. et al. 2007)). Poorly quantified emission factors and low understanding of when various aerosol emissions are likely to form during a fire event (initiation, combustion, extinguishing) inhibit

Participation in exercise-based cardiac rehabilitation is related to reduced total mortality in both men and women : Results from the SWEDEHEART registry

Aims: Participation in exercise-based cardiac rehabilitation (exCR) increases aerobic capacity and improves outcomes in patients following myocardial infarction (MI) and is therefore universally recommended. While meta-Analyses consistently report that participation in exCR reduces cardiovascular mortality, there are conflicting results regarding effects on total mortality. Presently, many eligibl

Assessing laser ablation multi-collector inductively coupled plasma mass spectrometry as a tool to study archaeological and modern human mobility through strontium isotope analyses of tooth enamel

To evaluate the possibility of obtaining detailed individual mobility data from archaeological teeth, the strontium isotope ratios on 28 human teeth from three separate Early-Mid Holocene, Swedish, foraging contexts (Norje Sunnansund, Skateholm and Västerbjers) were analysed through laser ablation. The teeth/individuals have previously been analysed using traditional bulk sampled thermal ionisatio

A potential wearable solution for preventing heat strain in workplaces : The cooling effect and the total evaporative resistance of a ventilation jacket

The increase in average seasonal temperatures has an impact in the occupational field, especially for those sectors whose work activities are performed outdoors (agricultural, road and construction sectors). Among the adaptation measures and solutions developed to counteract occupational heat strain, personal cooling garments represent a wearable technology designed to remove heat from the human b

Housing Matters for People with Parkinson´s disease. Accessibility, Meaning, Control and Activities of Daily Living

Parkinson´s disease (PD) is one of the most common neurological diseases with both motor and non-motor symptoms that can be perceived as difficult to control despite medical treatment. This leads to several consequences in everyday life for example difficulties in activities of daily living (ADL), sometimes already at diagnosis. Therefore, rehabilitation is important to manage the consequences of