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The entire world is facing the stiff challenge of COVID-19 pandemic. To overcome the spread of this highly infectious disease, several short-sighted strategies were adopted such as the use of broad-spectrum antibiotics and antifungals. However, the misuse and/or overuse of antibiotics have accentuated the emergence of the next pandemic: Antimicrobial resistance (AMR). It is believed that pathogens
Aeolian transport rates decreases during wet conditions as the threshold shear velocity for initiation of transport increases over moist sand. This study investigates the influence of surface moisture on meso-scale aeolian transport simulations. Yearly transport rates towards the dunes are simulated with ten different threshold-based models to account for moisture effects. The ten models show larg
In 2020, the European Parliament (ep) issued a resolution calling for all European Union (EU) Member States to adopt feminist foreign and security policies, and for a gender-transformative vision in the EU’s own external policy. Drawing on the literatures on negotiations and norm contestation, this article3 asks why the resolution was so progressive. It also asks how we can characterize and explai
The placenta contains a large variety of metabolizing enzymes, among them UDP-glucuronosyltransferase (UGT). Several UGT2B isozymes have so far been detected in human placenta, but little is known on placental expression of UGT1A isozymes. The antiepileptic drug lamotrigine (LTG) is a UGT1A4-substrate, and its serum concentration falls by over 50% during pregnancy, leading to impaired seizure cont
Annual rates of adrenalectomy have doubled in the last 20 years as a consequence of increased detection of adrenal incidentalomas, improved biochemical diagnosis, genetic screening, and minimally invasive surgical techniques. Most adrenal incidentalomas are benign non-functional adrenocortical adenomas. Functional adrenal tumours are associated with high morbidity if left untreated, and this may b
The success of establishing bioeconomies replacing current economies based on fossil resources largely depends on our ability to degrade recalcitrant lignocellulosic biomass. This study explores the potential of employing various enzymes acting synergistically on previously pretreated agricultural side streams (corn bran, oat hull, soluble and insoluble oat bran). Degrees of synergy (oligosacchari
Abstract in Spanish:Este estudio presenta un análisis de las cubiertas de una selección de novelas negras suecas, publicadas en Grecia y en el mundo hispanohablante durante el periodo de 2000-2017. Las imágenes de cubierta son importantes en el sistema paratextual (Genette, 1991); a partir de las teorías sobre el paratexto aplicadas al campo de los estudios de traducción, proponemos comparar las cThis study is an analysis of the book cover images of a selection of Swedish crime literature, published in Greece and the Spanish-speaking world in the period of 2000-2017. Covers are crucial to the paratextual signal system (Genette, 1991); departing from theories on paratext within translation studies, we aim to compare the original book covers to the covers of the translated volumes. Do the Gr
BACKGROUND: From the beginning of COVID-19 pandemic, pregnant women have been considered at greater risk of severe morbidity and mortality. However, data on hospitalized pregnant women show that the symptom profile and risk factors for severe disease are similar to those among women who are not pregnant, although preterm birth, Cesarean delivery, and stillbirth may be more frequent and vertical tr
Background: The WHO-recommended tuberculosis screening and diagnostic algorithm in ambulatory people living with HIV is a four-symptom screen (known as the WHO-recommended four symptom screen [W4SS]) followed by a WHO-recommended molecular rapid diagnostic test (eg Xpert MTB/RIF [hereafter referred to as Xpert]) if W4SS is positive. To inform updated WHO guidelines, we aimed to assess the diagnost
BACKGROUND: The global prevalence of dementia is rapidly expanding and is expected to triple by 2050. Approximately 45 % of dementia cases are estimated to be attributable to potentially modifiable risk factors. Identifying how these factors contribute to specific brain pathologies may improve strategies to reduce dementia incidence.OBJECTIVES, DESIGN, SETTING: The aim of this study was to identif
Objective: To report the use of a percutaneous carotid access with vessel closure devices (VCDs) during complex endovascular aortic arch repair. Methods: Seven international high-volume centers conducted a retrospective review of all patients receiving percutaneous carotid access with VCD during endovascular aortic arch procedures to investigate its feasibility and safety. The primary end point wa
This article examines changes in the repertoire of contention in Sweden during the crucial years of democratisation. Based on a dataset of applications to organise public marches in Stockholm 1887-1920, the study looks at the overall trends in the political use of demonstrations: which organisations applied to stage demonstrations and which organisations obtained permission from the authorities. T
This paper is concerned with the salience of discourse referents from both a hearer and a speaker perspective in the context of negative quantifying expressions (e.g. not all, few) in Swedish. In three sentence completion studies we investigated what discourse referent is most salient from each of these perspectives and how salience is affected by the syntactic form/semantic type (entity vs. propo
IMPORTANCE: Breast cancer (BC), the most prevalent cancer among women globally, is a heterogeneous disease, with prognosis differing by estrogen receptor (ER) status. Having a family history of BC increases the risk of BC; however, it is unclear whether family history is associated with the prognosis of overall and ER-specific BC.OBJECTIVE: To assess whether a family history of BC is associated wi
Small neutral organic compounds have traditionally the role of EOF markers in electrophoresis, as they are expected to have zero electrophoretic mobility in external electric fields. The BGE contains, however, ions that have unequal affinities to the neutral molecules, which in turn results in their mobilization. In this study we focused on two EOF markers-thiourea and DMSO, as well as on N-methyl
Purpose: Identifying biomarkers of radiotherapy (RT) response is important for optimizing the treatment of early breast cancer. In this study, we tested the interaction between endothelial cell (EC) expression of phospho-Tyr397-FAK (pY397-FAK) and adjuvant-RT on clinical outcomes after breast-conserving surgery (BCS) within a randomized study. Preclinical data suggest an enhanced effect of RT on l
Leaders’ debates have become a feature of contemporary election campaigning. While an historical feature of the US landscape, in the United Kingdom, they are a more recent phenomenon. The second UK 2015 general election leadership debate comprised seven candidates, of which three were women. Using qualitative thematic analysis and adopting the notion that gender is ‘performed’, we explore three fe
The 8B+64Zn reaction at 38.5 MeV has been studied at HIE-ISOLDE CERN to investigate proton halo effect on the reaction dynamics. For the first time it was used the only existing post-accelerated 8B beam. The measured elastic scattering angular distribution showed a small suppression of the Coulomb-nuclear interference peak, opposite to what observed for the one-neutron halo nucleus 11Be on the sam
This article argues that, in 1QHa 11:20-27; 20:27-39 and Sir 33:7-15, the use of allusions to humanity's creation from dust in Genesis 2-3 and to its formation from clay in Isa 29:16; 45:9; Jer 18:4, 6 represents a conscious exegetical process in which the Genesis and prophetic traditions were read and used in light of one another. Although originating within different social environments - one se
