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Popular Abstract in Swedish Avhandlingen syftar till att utifrån 11-åriga barns berättelser om sina familjer och hur de själva uppfattar sina familjer och sin fostran beskriva, analysera, förstå och tolka villkoren för denna fostrans- och socialisationsprocess samtidigt som den pågår. Forskningsproblemet kan formuleras: hur och vad uppfattar och berättar barn om sina upplevelser av familjeliv och The thesis aims to describe, analyse and interpret the conditions of the upbringing process and the socialization process in a group of eleven-year-olds while the process is still ongoing, and to do this with the help of the eleven-year-olds? narrations about their families and about how the children themselves view their families and their upbringing. The research approach is inspired by phenomen

This book commemorates the 65th birthday of Karl Johan Åström, who is professor in Automatic Control at Lund Institute of Technology. Karl Johan Åström is one of the leading researchers of the world in automatic control. The contributions are chosen to illustrate some of the areas where Karl Johan Åström has been active in his research. The idea of the papers is also to point out new directions wi

In Sweden, the combination of the country’s natural ecological vulnerability to acidification and its geographical location has been domestic focal points for the treatment of the ‘acid rain’ issue. Political interest in the acidification issue in Sweden emerged in the late 1960s, when the problems of long-range transport of sulphuric compounds and their harmful environmental effects were first hi

Popular Abstract in Swedish Blodbildande stamceller förekommer i mänsklig benmärg i en frekvens på ca 1/100 000 celler. Med hjälp av cellytemarkörer, t.ex. CD34, kan man rena fram cellpopulationer som är anrikade på stamceller, men det saknas exakt kunskap om hur enskilda stamceller ser ut. De blodbildande stamcellerna har förmåga att vid celldelning antingen förnya sig själva eller att mogna ut. Hematopoietic stem cells (HSCs) have the capacity to maintain hematopoiesis throughout life. HSCs are ideal targets for permanent gene transfer, as the transgene will be expressed in all the progeny of the gene-modified stem cells. The aim of this thesis was to optimize conditions for retroviral gene transfer to human candidate HSCs and to study mechanisms interfering with efficient gene transfer.

Popular Abstract in Swedish SAMMANFATTNING PÅ SVENSKA Grupp B streptokocker (GBS) Grupp B streptokocker (GBS), på latin Streptococcus agalactiae, är det vanligaste fyndet vid bakteriella infektioner, som blodförgiftning (sepsis), hjärnhinneinflammation (meningit) och lunginflammation (pneumoni) hos nyfödda barn. Sjukdomsförloppet är ofta våldsamt och livshotande. Sedan 1970-talet har det skett enABSTRACT Streptococci constitute a heterogeneous group of Gram-positive bacteria, divided into different serological groups on the basis of antigenic differences in a cell wall-associated carbohydrate. This thesis describes related surface proteins expressed by bacteria in two of these groups, the group B streptococcus (GBS) and the group A streptococcus (GAS). GBS is an encapsulated bacterium th

Replacing fossil fuels by biofuels and increasing energy efficiency are often considered to be options for reducing the net emission of greenhouse gases. This thesis presents the results of analyses of energy efficiency, emission and cost of whole energy system chains, from the natural resource to the end user when heating detached houses in a Swedish context. External costs and taxes of the energ

Combining the strengths of an advanced mathematical model of human physiology and a thermal manikin is a new paradigm for simulating thermal behaviour of humans. However, the forerunners of such adaptive manikins showed some substantial limitations. This project aimed to determine the opportunities and constraints of the existing thermal manikins when dynamically controlled by a mathematical model

This thesis is a study of landownership that took place in Scania in southern Sweden in the 1860s. Basically it was a conflict between an alliance of tenant farmers and rural poor against estate owners in a time of agrarian change, a time characterized by mass evections of tenants and increasing proletarization. The participants of the movement, led by the self-taught lawyer Samuel Tullberg, claim

Popular Abstract in Swedish En främre korsbandsskada i knäet betraktas allmänt som en ganska allvarlig knäskada med risk för kvarstående funktionsnedsättning. Sett över tiden finns även en ökad risk för artros, ”brosknedbrytning”, efter främre korsbandsskada. Traditionellt sett har man inom ortopedin främst diskuterat vikten av främre korsbandets mekaniskt stabiliserande funktion; en skada, rupturProprioceptive ability was estimated in different groups of patients with anterior cruciate ligament (ACL) injury as well as in different groups of healthy uninjured individuals. In study I, patients with poor outcome of the ACL injury – i.e. persistent symptoms of instability – were compared with patients with few symptoms after ACL injury, as well as with a control group. The results showed that

The purpose of this thesis is to characterize the health status of the population in early Lund. This is pursued by an osteological analysis of 3.305 individuals fron three time periods: c. 990-1100, c. 1100-1300 and c. 1300-1536. The individuals derives from cemeteries connected to four neighbouring churches, where one is the sucessor of the other (Trinitatis). One cemetery (Kattesund) is by and

Popular Abstract in Swedish Mesenteriell ischemi (nedsatt blodcirkulation till tarm och övriga bukorgan) är vanligt förekommande vid ett flertal olika sjukdomstillstånd som t ex blödnings-, septisk och cirkulatorisk chock. Inte minst är tarmen mycket känslig för nedsättning av blodflödet. Tarmskadan, inkluderande dess barriär(skydds-)funktion sker dels under perioden med nedsatt blodförsörjning meIntestinal ischemia and reperfusion (I/R) is not infrequent in the clinical situation and the intestinal barrier plays an important role in gut barrier function, preventing not at least septic complications and potentially the development of the multiple organ dysfunction syndrome. Mechanisms of intestinal I/R induced gut epithelial and endothelial barrier dysfunction and remote organ dysfunction

Popular Abstract in Swedish Organiska miljögifter finns idag i hela världen och har spridits dels genom lokala utsläpp och dels genom atmosfärisk transport. Trots att flera miljögifter (som insektsmedlet DDT och industrikemikalien PCB) har varit förbjudna sedan början av 1970-talet ser vi fortfarande höga halter av miljögifter i vår natur. Dels beror detta på att organiska miljögifter är svårnedbrAtlantic salmon (Salmo salar) from the Baltic Sea suffer from a reproduction disease known as the M74-syndrome. Newly hatched fry develop nerve disorders and die between 3-5 days after the first symptoms are seen. This is a maternally transmitted disease that is casued by a thiamine (vitamin B1) deficiency. The factor(s) that casue(s) this thiamine deficiency are largely unknown. However, several

In patchily distributed species dispersal connects local populations into metapopulations. Reliable quantifications of dispersal are therefore crucial to understanding the population dynamics and genetic structure of such metapopulation systems. The great reed warbler (Acrocephalus arundinaceus) inhabits eutrophic lakes and has a patchy breeding distribution. In this study we investigated the disp

Background., Hypertrophic cardiomyopathy is a common cause of sudden death in children. In this study, we aimed to identify clinical measures for stratification of this risk in childhood. Patients and methods: By means of a retrospective cohort study from six regional centres of paediatric cardiology, we identified 128 patients with hypertrophic cardiomyopathy presenting below 19 years of age, wit

Percutaneous physiodesis is an established technique for treating mild leg-length discrepancy and problems of expected extreme height. Angular deformities resulting from incomplete physeal arrest have been reported, and little is known about the time interval from percutaneous physiodesis to actual physeal arrest. This procedure was carried out in ten children, six with leg-length discrepancy and

Objective. Hemophilic arthropathy, with characteristics of inflammatory (rheumatoid arthritis) and degenerative (osteoarthritis) joint damage, occurs at an early age, is associated with minor comorbidity, and is restricted to 3 pairs of large joints. The aim of this study was to determine whether commonly used serum and/or urinary biomarkers of cartilage and bone turnover for which assay kits are

During the initial indolent chronic phase of chronic myeloid leukemia (CML), the t(9;22)(q34;q11), resulting in the Philadelphia chromosome (Ph), is usually the sole cytogenetic anomaly, but as the disease progresses into the accelerated phase (AP), and eventually into aggressive blast crisis (BC), secondary aberrations, mainly unbalanced changes such as +8, i(17q), and +Ph, are frequent. To date,

Steryl esters and triacylglycerol (TAG) are the main storage lipids in eukaryotic cells. In the yeast Saccharomyces cerevisiae, these storage lipids accumulate during stationary growth phase within organelles known as lipid bodies. We have used single and multiple gene disruptions to study storage lipid synthesis in yeast. Four genes, ARE1, ARE2, DGA1, and LRO1, were found to contribute to TAG syn