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Framtida app för 'den okända resan'

Public transport affects people on a daily basis and therefore it is important for the public transport sector to improve the user experience for travellers. Simplicity is a keyword in the improved user experience where mobile solutions play an important role for the experience. The aim in this master thesis is to explore ways how to use a smartphone to make it easier for travellers and how to pre

The Identifiability of Osteological Traits on 3D Models of Human Skeletal Remains

Previous studies have entertained the prospect of having 3D models substitute for their dry bone originals in osteological analysis. The objective of this study was to contribute to qualifying to what extent this may be possible given current technology. To this purpose, rather than choosing just a quantitative and purely technical method for evaluating models, as has been the norm in previous stu

Construction and benchmarking of adaptive parameterized linear multistep methods

A recent publication introduced a new way to define all k-step linear multistep methods of order k and k+1, in a parametric form that builds in variable step-size. In this framework it is possible to continuously change method and step-size, making it possible to create better behaving adaptive numerical solvers. In this thesis general numerical solvers based on this framework have been implemente

Developing business opportunities for biological by-products

A growing middle class and increased consumption call for better utilization of resources. For companies to make use of all resources in the production system is not only a way of meeting the changing customer demands and regulatory changes regarding sustainability, but also a way of increasing profits. Finding new business opportunities for by-products can be considered as early stage innovation,

Industrial Networks in the Context of Chinese Indigenous Innovations: A Case Study in the Chinese Information and Communications Technology Industry

Purpose: The purpose of this study is to deepen the understanding of industrial networks in the context of Chinese indigenous innovation policies. More specifically, it is the intention to explore which relationships of Chinese ICT firms with various business and non-business actors can facilitate directly or indirectly its innovativeness. Attention is also paid to the impact of overall innovation

Omhändertagande och rehabilitering vid främre korsbandsskador ur ett svenskt och österrikiskt perspektiv - en kvalitativ pilotstudie

Background: Anterior cruciate ligament injury is a common knee injury and the treatment may be surgical and/or conservative. Different studies have shown surgical and conservative treatment, respectively, as the best intervention. Therefore it is uncertain which treatment is preferable. When searching in PubMed, no articles were found describing the thoughts and experiences of orthopedists and phy

Synthesis and Characterization of Poly(phenylene oxide) Functionalized with various Imidazolium Cations via Alkyl Spacer units

Anjonbytarmembran bestående av polyfenylenoxid funktionaliserad med följande imidasolgrupper, 1-metylimidasol (MeIm), 1,2,4,5-tetrametyl-1H-imidasol (TMeIm), imidaso[1,2-a]pyridin (ImPyr), 1-metylbensimidasol (MeBim) och 1-metyl-mesitylbensimidasol (MeMesBim), via en alkyl kedja tillverkades och analyserades med avseende på följande egenskaper; anjonisk ledningsförmåga, vattenabsorption, katjonaggAnion exchange membranes consisting of a Poly(phenylene oxide) polymer backbone functionalized with various imidazolium cations, 1-methylimidazole, 1,2,4,5-tetramethyl-1H-imidazole, imidazo[1,2-a]pyridine, 1-methylbenzimidazole and 1-methyl-mesitylbenzimidazole, via alkyl spacer units were prepared and analyzed for anion conductivity, water absorption properties, cation aggregation, thermal stabil

Efficacy and safety of oral alitretinoin (9-cis retinoic acid) in patients with severe chronic hand eczema refractory to topical corticosteroids: results of a randomized, double-blind, placebo-controlled, multicentre trial

Background Patients with severe chronic hand eczema (CHE) refractory to topical corticosteroids currently have limited treatment options suited for chronic use, and few controlled clinical studies have investigated new therapies in this setting. Objectives To assess the efficacy and safety of oral alitretinoin (9-cis retinoic acid) taken at 10 mg or 30 mg once daily for up to 24 weeks, compared wi

Equilibrium aspects of polycation adsorption on silica surface: How the adsorbed layer responds to changes in bulk solution

Adsorption of cationic high molecular weight polyacrylamides (CPAM) (M-w is about 800 kDa) with different fractions of cationic units tau = 0.09 and tau = 0.018 onto silica surface was studied over a wide range of pH (4-9) and KCl concentration (c(s) = 10(-3)-10(-1) M) by in-situ null ellipsometry. We discuss how the adsorbed layer depends on the bulk conditions as well as kinetically responds to

Assessment of spatial BOLD sensitivity variations in fMRI using gradient-echo field maps.

Clinical blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) is becoming increasingly valuable in, e.g., presurgical planning, but the commonly used gradient-echo echo-planar imaging (GE-EPI) technique is sometimes hampered by macroscopic field inhomogeneities. This can affect the degree of signal change that will occur in the GE-EPI images as a response to neural

Essentials of Nursing Care in Randomized Controlled Trials of Nurse-Led Interventions in Somatic Care: A Systematic Review

Background: Nursing practice has to contribute to evidence pointing out why there is a need for more nurse-designed randomized control trials (RCTs) focusing on evidence-based practice (EBP).How far this EBP has progressed in different health aspects is usually established by systematic reviews of RCTs. Nurse-led RCTs exist but no study has addressed the essentials of nursing care. Aim: The aim wa

Prevalence of Doctor-Diagnosed Thumb Carpometacarpal Joint Osteoarthritis: An Analysis of Swedish Health Care

Objective. While the prevalence of radiographic thumb carpometacarpal (CMC1) osteoarthritis (OA) is well-described, little is known about clinically symptomatic disease presenting to physicians for care. We sought to determine the prevalence of doctor-diagnosed CMC1 OA. Methods. Using health care data from Skane in southern Sweden (population 1.24 million), we identified all adults ages >= 20 year

Prognostic and chemotherapy predictive value of gene-expression phenotypes in primary lung adenocarcinoma.

Purpose Primary lung adenocarcinoma remains a deadly disease. Gene expression phenotypes (GEPs) in adenocarcinoma have potential to provide clinically relevant disease stratification for improved prognosis and treatment prediction, given appropriate clinical and methodological validation. Experimental Design 2395 transcriptional adenocarcinoma profiles were assembled from 17 public cohorts and cla

Predictive role of plasma vascular endothelial growth factor for the effect of celecoxib in advanced non-small cell lung cancer treated with chemotherapy

Aim of the study: The primary purpose of this study is to investigate if pretreatment plasma levels of vascular endothelial growth factor (VEGF) are predictive of the effect of celecoxib on survival in advanced non-small cell lung cancer (NSCLC) treated with palliative chemotherapy. A secondary objective is to describe the course of plasma VEGF levels during and after treatment with cytotoxic chem

Time-resolved spectroscopic study of photofragment fluorescence in methane/air mixtures and its diagnostic implications

In this work 80-picosecond laser pulses of 266-nm wavelength with intensities up to (2.0 +/- A 0.5) x 10(11) W/cm(2) were used for fragmentation of methane/air gas mixtures at ambient pressure and temperature. Emission spectra are, for the first time, studied with ultrahigh temporal resolution using a streak camera. Fluorescence spectra from CH(A(2)Delta-(XI)-I-2 , (BI)-I-2 (-)-(XI)-I-2 pound , (C

Attention, executive functions, and mentalizing in anorexia nervosa eighteen years after onset of eating disorder

Objective: Prospective study of attention, executive functions, and mentalizing abilities in a representative sample of teenage-onset anorexia nervosa (AN). Method: A total of 51 AN cases recruited after community screening were contrasted with 51 matched comparison cases 18 years after AN onset. Neuropsychological tests had been done at 21, 24, and 32 years (18 years after AN onset). Results: The

Doubly reactive INS-IGF2 autoantibodies in children with newly diagnosed autoimmune (type 1) diabetes.

The splice variant INS-IGF2 entails the preproinsulin signal peptide, the insulin B-chain, eight amino acids of the C-peptide and 138 unique amino acids from an ORF in the IGF2 gene. The aim was to determine whether levels of specific INS-IGF2 autoantibodies (INS-IGF2A) were related to age at diagnosis, islet autoantibodies, HLA-DQ, or both, in newly diagnosed type 1 diabetes patients and controls

Comparative effectiveness and survival of infliximab, adalimumab, and etanercept for rheumatoid arthritis patients in the Hellenic Registry of Biologics: Low rates of remission and 5-year drug survival

Objective: To compare effectiveness, drug survival, and safety between infliximab, adalimumab, and etanercept, in a nationwide cohort of rheumatoid arthritis (RA) patients. Methods: This study is a prospective cohort study of 1208 active RA patients. Effectiveness, drug survival, and serious adverse events during entire follow-up (median 2.9 years) were monitored. Results: EULAR and CDAI responses

Health-related quality of life is impaired in active collagenous colitis

Objectives: The characteristic clinical symptoms of collagenous colitis are non-bloody diarrhoea, urgency and abdominal pain. Treatment is aimed at reducing the symptom burden and the disease impact on patients' health-related quality of life. The objective of this study was to analyse health-related quality of life in patients with collagenous colitis. Methods: In a cross-sectional, postal HRQL s