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In two recent double-blind clinical trials of fetal ventral mesencephalic cell transplants into the striatum in patients with Parkinson's disease (PD), a significant proportion of the grafted patients developed dyskinetic side effects, which were not seen in the sham operated patients. Comparison between dyskinetic and non-dyskinetic grafted patients in one of the trials suggested that an uneven p

Previously genome-wide association methods in patients with classic bladder exstrophy (CBE) found association with ISL1, a master control gene expressed in pericloacal mesenchyme. This study sought to further explore the genetics in a larger set of patients following-up on the most promising genomic regions previously reported. Genotypes of 12 markers obtained from 268 CBE patients of Australian,

Extracellular signal-regulated kinase 2 (ERK2) is located in the cytoplasm of resting cells and translocates into the nucleus upon extracellular stimuli by active transport of a dimer. Passive transport of an ERK2 monomer through the nuclear pore is also reported to coexist. We attempted to characterize the cytoplasmic retention and nuclear translocation of fusion proteins between deletion and sit

BACKGROUND: Aortic dissection type A requires immediate surgery. In general surgery populations, patients operated during weekends have higher mortality rates compared to patients operated on weekdays. The weekend effect in aortic dissection type A has not been studied in detail.METHODS: The Nordic Consortium for Acute Type A Aortic Dissection (NORCAAD) registry includes patients (N=1,159) who und

In the philosophy of J. L. Schellenberg, “evolutionary religion” is a religious stance oriented towards the deep future. According to Schellenberg, the best form of evolutionary religion is non-doxastic faith in ultimism. I reject Schellenberg’s arguments for preferring ultimism and suggest that committing non-doxastically to traditional religion makes more sense from an evolutionary perspective.

Earlier studies have shown that when assessing explanations of psychological phenomena, there is a bias for explanations including references to neuroscience, even when these references contain logically irrelevant information (Fernandez-Duque, Evans, Christian & Hodges, 2015; M inahan & Siedlecki, 2016; Weisberg, Keil, Goodstein, Rawson and Gray, 2008; Weisberg, Taylor & Hopkins, 2015

Sepsis is a life threatening condition where the body’s reaction to an infection results in a dysregulated immune response - ultimately causing damage to tissues and organs. The syndrome is diverse, both in underlying biology, disease manifestation and severity, and is therefore divided into endotypes and further into subphenotypes. Further understanding of the biological pathways of the various s

Functional Magnetic Resonance Imaging, fMRI, is a non invasive method to map brain activation with a magnetic resonance camera. In this thesis we propose a method to deal with motion induced artefacts in functional fMRI, using Independent Component Analysis, ICA. Patient movement can induce false activation or cause loss of true activation. Movement is one of the most common causes of fMRI failure

Nowadays, the supply of electronic services constitutes an important part of commerce over the Internet and is expected to grow significantly in the future. Taxing the consumption of electronic services has proven not to be an easy task, especially in regard to its provision for non-taxable persons. In the European Union the approach is to tax them at destination (though intra-Community supplies a

As an international actor it is preferable to make an effort to understand how your performance affects the long-term sustainability, both in local and global terms. Sustainability includes subjects such as integration between economical, social and environmental spheres. It can be achieved by reorganizing living conditions, reappraising economic sectors and work practices, develop technologies in

Bärighetsmätningar är avgörande för att bedöma vägars kapacitet att hantera ökande trafikbelastningar. Enligt Trafikverket förväntas en ökning av personbilar med 27%, bussar med 17% och godstransporter med 46% fram till år 2040. Denna prognostiserade tillväxt leder till ökat vägslitage vilket i sin tur kräver mer omfattande underhåll och komplexare åtgärder i högtrafikerade områden. Traditionellt

In recent years the concept of “Blue carbon” has brought attention to the importance of Mangroves, Seagrass and Saltmarsh ecosystems in carbon cycles. Concerns over climate change has had countries commit to decreasing CO2 emissions, often using natural processes to sequester CO2. This trend has often followed a market approach through creating a monetary value and market for CO2. This Climate Fin

Research question: How do employees at call centres perceive algorithmic management? Purpose: This study aims to provide insights into how employees in a call centre perceive algorithmic management. Methodology: The study employed a qualitative research method, incorporating interviews with a relativist and social constructionist perspective, to fulfill its purpose and address the research questio

When I began to study at the Academy of Music in Malmö, I found myself in a playing situation where I could not bring my full amplifier rig but just my electric guitar to ensemble lessons. Since I was familiar with my sound, I found difficulties to play on other amplifiers. So I began to research and learn on electric guitar and amplifier's world all over again. Many times I felt the frustrati