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Antibody-mediated blockade of CTLA4 has been shown to be effective in treating a select group of patients with late-stage melanoma. The precise mechanism underlying the clinical activity of CTLA4 immunotherapy is poorly understood, although recent experimental findings indicate that antibody-mediated depletion of regulatory T cells (Tregs) in the tumor microenvironment plays a key role in efficaci
Though there currently exists numerous ways and suggestions of how to measure emissions in transportation, companies struggle to accurately quantify their greenhouse gas emissions to make sound and green decisions. It is difficult to determine what to measure, how to measure and why to measure in a certain way. Hence, the purpose of this master thesis was to develop a performance measurement frame
The purpose of this study is to investigate the increasing specialisation of tasks in contemporary organisations and ensuing demand of expertise, and how these factors are affecting the leadership within virtual teams (teams in organisations working virtually with help of technology). Globalisation and a technological revolution has greatly transformed the business world during the last decades, w
BACKGROUND: Currently, there are no therapies targeting specific pathogenic pathways in myocarditis. IL (interleukin)-1 blockade has shown promise in preclinical studies and case reports. We hypothesized that blockade of IL1RAP (IL-1 receptor accessory protein), a shared subunit of the IL-1, IL-33, and IL-36 receptors, could be more efficient than IL-1 blockade alone. METHODS: We induced coxsackie
Background: Older adults with pain have an increased risk of falling (odds ratio (OR) 1,7). Pain in Parkinson’s disease (PD) is more common than in older adults. The association between pain and falling in people with PD is poorly explored.Objective: To investigate the occurrence of pain in mild PD and its association with future falls/near fallsMethods. The study included 141 participants with PDBackground: Older adults with pain have an increased risk of falling (odds ratio (OR) 1,7). Pain in Parkinson’s disease (PD) is more common than in older adults. The association between pain and falling in people with PD is poorly explored.Objective: To investigate the occurrence of pain in mild PD and its association with future falls/near fallsMethods. The study included 141 participants with PD
The purpose of the study was to gain a better understanding of informal leadership on the flight deck and how leadership can be effectively practiced by a first officer from the right seat, with the intention to strengthen team performance. The research question tried to answer if informal leadership is present on the flight deck and what factors contribute to the first officer’s ability to influe
Purpose: The main objective of this thesis is to examine the effect different drivers of agency costs have on corporate cash holdings in public and private German technology firms. The analysis identifies three potential sources of agency costs. By determining target cash levels first and then obtaining deviations from these targets, the influences of agency costs are measurable. Data Set: The sam
IntroductionCardiac arrest (CA) survivors often face significant health challenges, including insomnia, which can adversely affect their health-related quality of life. The Minimal Insomnia Symptom Scale (MISS) is a brief, self-reported instrument designed to screen for insomnia. This study aimed to identify the measurement properties of the MISS in CA survivors and to explore a relevant cut-off s
The study aims to gain an increased understanding of and insight into CBT psychotherapists ́ experiences of what is effective in psychotherapeutic treatment. A perspective of interest based on the fact that psychotherapists ́ experiences of what is effectivehave not previously been taken into account in research, that in the therapist ́s everyday life there may be a clash between theory and practi
Reaching and grasping impairments significantly affect the quality of life for people who have experienced a stroke or spinal cord injury. The long-term well-being of patients varies greatly according to the restorable residual capabilities. Electrical stimulation could be a promising solution to restore motor functions in these conditions, but its use is not clinically widespread. Here, we introd
Body appreciation-unappreciation and body satisfaction-dissatisfaction are in the literature seen as conceptually different, but construct distinction has only been supported using qualitative methods. Because of limits in using Likert-style questionnaires to measure multidimensional constructs, quantitative research has yet to directly demonstrate that it is possible to appreciate the body withou
CFE-Paper A5 ver 7 1Hollywood Horror: Europe as American Dystopia Hollywood Horror: Europe as American Dystopia Michael Tapper Michael.Tapper@swipnet.se 2 CFE Working paper series no. 7 CENTRE FOR EUROPEAN STUDIES AT LUND UNIVERSITY: Box 52 Phone: +46 (0)46-222 88 99 SE-221 00 LUND Fax: +46 (0)46-222 40 06 Sweden Email: cfe@cfe.lu.se CFE Working paper series is published by Centre for European Stu
https://www.cfe.lu.se/en/sites/cfe.lu.se.en/files/2020-12/cfewp07.pdf - 2026-07-23
Scientific abstract: The study set out to investigate diurnal patterns in methane flux in a fen in Kobbefjord, Southwest Greenland and to link these to physical and biological parameters in the environment. Methane flux was measured using six chambers which recorded the flux every ten minutes from spring to autumn. Methane flux data from 2009 and 2010 were compared to photosynthetically active radA study of diurnal variations in methane flux in a fen in Kobbefjord in Southwest Greenland is presented. Four separate periods, each of one week, from the growing seasons of 2009 and 2010 were chosen. Methane flux data were compared to surface temperature, soil temperature and photosynthetically active radiation (PAR). Regression tests between surface temperature and methane flux produced highly
How do we design policies that support a shift in eating habits towards a diet that includes more vegetable-basedproducts and less meat, and in particular red meat? To inform policy, more information is needed about consumers’perceptions of the plant-based protein alternatives that have become available on the market. The present study of 1000 Danish consumers examined oat drink and plant-based miHow do we design policies that support a shift in eating habits towards a diet that includes more vegetable-based products and less meat, and in particular red meat? To inform policy, more information is needed about consumers' perceptions of the plant-based protein alternatives that have become available on the market. The present study of 1000 Danish consumers examined oat drink and plant-based
The COVID-19 pandemic caused universities worldwide, including those in Sweden, to adopt online distance learning as the primary teaching approach. However, there is limited research on how larger environmental changes affect university students’ occupational balance. In this study, 15 university students were interviewed, and their responses were analyzed using qualitative content analysis. The f
This study investigates patterns of seasonal variation in hours worked by women employed in home-based industrial production in Sweden in the early 20th century. Previous studies often describe workers in this type of production as the most flexible segment of industrial workers, and highly dependent on seasonal fluctuations in supply and demand. However, few have studied this empirically. This stThis study investigates patterns of seasonal variation in hours worked by women employed in home-based industrial production in Sweden in the early 20th century. Previous studies often describe workers in this type of production as the most flexible segment of industrial workers, and highly dependent on seasonal fluctuations in supply and demand. However, few have studied this empirically. This st
